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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …"
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Increasing the air flow between buildings in high density urban areas in Ras Al-Khaimah, UAE
منشور في 2008"…This research is a study of how to increase the flow of natural ventilation in a high density urban area. …"
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Perceptions of Science Teachers Regarding Instruction that Increase High School Students' Motivation to Learn Science in Al Ain City
منشور في 2023"…The current study was carried out to investigate the high school science teachers’ perceptions regarding instruction that increases high school students’ motivation to learn science in Al Ain City. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…"
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Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex
منشور في 2022"…<p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a>, published online 22 July 2022.…"
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Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection?
منشور في 2021"…<h3>Introduction</h3><p dir="ltr">Neuropilin-1(NRP1) is a cofactor that enhances SARS-CoV-2 coronavirus cell infectivity when co-expressed with angiotensin-converting enzyme 2(ACE2). …"
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Human Recombinant Arginase I (Co)-PEG5000-Induced Arginine Depletion of Breast Cancer Cell Lines Causes Autophagy Mediated Cell Death
منشور في 2024"…Overall, these findings suggest that [HuArgI(Co)-PEG5000] is a potent therapeutic agent for breast cancer, leveraging the autophagy pathway to selectively induce cytotoxicity in ASS1-expressing breast cancer cells. …"
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Resection of liver metastases from breast cancer
منشور في 2012"…On multivariate analysis, estrogen receptor–negative primary breast disease (P = .009; hazard ratio, 3.3; 95% confidence interval, 1.4–8.2) and preoperative progressive disease (P = .003; hazard ratio, 3.8; 95% confidence interval, 1.6–9.2) were associated with decreased overall survival. …"
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P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis
منشور في 2010"…As such, efflux pumps are a major obstacle to drug brain distribution. Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with little therapeutics available: riluzole is the only drug approved in its treatment. …"
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Application of Balance Scorecard for Assessing and Improving School Teacher’s Performance: A study in a Public School in Al Ain
منشور في 2019"…The balanced scorecard is a performance management tool to assess the performance of the teacher by considering four different aspects. …"
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Spatiotemporal mapping of groundwater salinity in Al-Batinah, Oman
منشور في 2021"…The aim of this study is to analyze the spatiotemporal variation of groundwater salinity in Al-Batinah governorate, a Sultanate of Oman, and the strategies to manage and control this problem in an effective way. …"
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Spatiotemporal mapping of groundwater salinity in Al-Batinah, Oman
منشور في 2021"…<p dir="ltr">The aim of this study is to analyze the spatiotemporal variation of groundwater salinity in Al-Batinah governorate, a Sultanate of Oman, and the strategies to manage and control this problem in an effective way. …"