Showing 701 - 720 results of 100,013 for search '(( 50 nn decrease ) OR ( 5 ((((wt decrease) OR (we decrease))) OR (a decrease)) ))', query time: 1.25s Refine Results
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    Decreased Integrity, Content, and Increased Transcript Level of Mitochondrial DNA Are Associated with Keratoconus by Xiao-Dan Hao (215742)

    Published 2016
    “…The relative mtDNA content of KC corneas was significantly lower than that of normal corneas (<i>P</i> = 9.19×10<sup>−24</sup>), possibly due to decreased expression of the mitochondrial transcription factor A (<i>TFAM</i>) gene (<i>P</i> = 3.26×10<sup>−3</sup>). …”
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    Image_2_SIRT1 haplo-insufficiency results in reduced cortical bone thickness, increased porosity and decreased estrogen receptor alpha in bone in adult 129/Sv female mice.tif by Hanna Artsi (777390)

    Published 2022
    “…</p>Methods<p>To investigate the mechanisms of gender differences in SIRT1 skeletal effect, we investigated femoral and vertebral cortical and cancellous bone in global Sirt1 haplo-insufficient 129/Sv mice aged 2,7,12 months lacking Sirt1 exons 5,6,7 (Sirt1<sup>+/Δ</sup>) and their wild type (WT) counterparts.…”
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    Image_1_SIRT1 haplo-insufficiency results in reduced cortical bone thickness, increased porosity and decreased estrogen receptor alpha in bone in adult 129/Sv female mice.tif by Hanna Artsi (777390)

    Published 2022
    “…</p>Methods<p>To investigate the mechanisms of gender differences in SIRT1 skeletal effect, we investigated femoral and vertebral cortical and cancellous bone in global Sirt1 haplo-insufficient 129/Sv mice aged 2,7,12 months lacking Sirt1 exons 5,6,7 (Sirt1<sup>+/Δ</sup>) and their wild type (WT) counterparts.…”
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    CD43<sup>-/-</sup> septic mice exhibit decreased frequencies of apoptotic CD4<sup>+</sup> and CD8<sup>+</sup> naïve T cells as compared to WT septic mice. by Katherine T. Fay (2576998)

    Published 2018
    “…B) CD43<sup>-/-</sup> septic mice exhibited a decreased frequency of apoptotic naïve CD4<sup>+</sup> T cells, defined as 7-AAD<sup>+</sup> Annexin V<sup>+</sup> CD44<sup>LO</sup> CD62L<sup>HI</sup> CD4<sup>+</sup> cells, compared to WT septic mice (11.8±1.6 vs 18.8±1.3, p = 0.002. …”
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    Downregulation of DOM decreases the abundance of PER and TIM. by Zhenxing Liu (399809)

    Published 2019
    “…Downregulation of DOM decreased PER levels at CT1-5 and CT17-21. (Scale bar: 50 um.) …”
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    The Type 2 Diabetes Risk Allele of <i>TMEM154</i>-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes by Marie Neergaard Harder (232759)

    Published 2015
    “…Significant associations between <i>TMEM154</i>-rs6813195 and the beta cell measures insulinogenic index and disposition index and between <i>FAF1</i>-rs17106184 and 2-hour serum insulin levels were selected for further investigation in additional Danish studies and results were combined in meta-analyses including up to 6,486 Danes.</p><p>Results</p><p>We confirmed associations with type 2 diabetes for five of the seven SNPs (<i>TMEM154</i>-rs6813195, <i>FAF1</i>-rs17106184, <i>POU5F1/TCF19</i>-rs3130501, <i>ARL15</i>-rs702634 and <i>ABCB9/MPHOSPH9</i>-rs4275659). …”