Difference in changes in VAS scores among three groups (n = 45). حسب Jae-Hong Kim (124622)

الموضوعات:

The parameter values for Langmuir, Freundlich and Temkin models for CR onto magnetic Co_0.5Mn_0.5Fe₂O₄ nanoparticles at different temperat... حسب Xiajun Zhang (3161865)

الموضوعات:

Electrically Controlled Lasing in Supercooled Liquid Crystal Blue Phase I Microdroplets حسب Gia Petriashvili (8920925)

"…When the electric field intensity is increased, the lasing intensity is increased too along with the linewidth that decreases from 6 to 2.5 nm. Besides, the laser lines were shifted toward the shorter wavelength by 11 nm. …"

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor حسب Anat Levit Kaplan (12126567)

"…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …"

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor حسب Anat Levit Kaplan (12126567)

"…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …"

Global level of 5mC and of H3K9ac in ovine SCNT embryos. حسب Parisa Nadri (13132252)

Bidirectional Optical Control of Proton Motive Force in Escherichia coli Using Microbial Rhodopsins حسب Kotaro Nakanishi (3389300)

"…Tethered cell experiments revealed that, upon illumination, the torque of the flagellar motor decreased to nearly zero (28 pN nm) with <i>Rm</i>XeR, while it increased to 1170 pN nm with AR3. …"

Bidirectional Optical Control of Proton Motive Force in Escherichia coli Using Microbial Rhodopsins حسب Kotaro Nakanishi (3389300)

"…Tethered cell experiments revealed that, upon illumination, the torque of the flagellar motor decreased to nearly zero (28 pN nm) with <i>Rm</i>XeR, while it increased to 1170 pN nm with AR3. …"

Bidirectional Optical Control of Proton Motive Force in Escherichia coli Using Microbial Rhodopsins حسب Kotaro Nakanishi (3389300)

"…Tethered cell experiments revealed that, upon illumination, the torque of the flagellar motor decreased to nearly zero (28 pN nm) with <i>Rm</i>XeR, while it increased to 1170 pN nm with AR3. …"

Bidirectional Optical Control of Proton Motive Force in Escherichia coli Using Microbial Rhodopsins حسب Kotaro Nakanishi (3389300)

"…Tethered cell experiments revealed that, upon illumination, the torque of the flagellar motor decreased to nearly zero (28 pN nm) with <i>Rm</i>XeR, while it increased to 1170 pN nm with AR3. …"

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... حسب Shuai Wang (109515)

"…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …"

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... حسب Shuai Wang (109515)

"…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …"

The decrease or inhibition of Hsp90 induced REST degradation. حسب Raúl Orozco-Díaz (7067624)

"…(D) The level of REST dramatically reduced in differentiated SH-SY5Y cells treated with GA (1 μM) or PU-H71 (50 nM) at 24 h. …"

MigC interacts with and decreases the activity of MurD. حسب Jeanette M. Critchlow (21553796)

Molecular Simulations Probing the Adsorption and Diffusion of Ammonia, Nitrogen, Hydrogen, and Their Mixtures in Bulk MFI Zeolite and MFI Nanosheets at High Temperature and Pressur... حسب Roshan Patel (10727011)

الموضوعات:

Retinoic acid decreases intracellular K⁺ in pectoral fin buds via transcriptional activation of the calcineurin inhibitor <i>rcan2</i>. حسب Xiaowen Jiang (8291814)

Ratio of inter- and intra-chromosome DSB clustering (inter/intra CD Ratio) for a range of simulated cell-types, LET (keV/<i>μ</i>m) and cluster radius (nm). حسب Samuel P. Ingram (9854133)

Water-Assisted Proton Transport in Confined Nanochannels حسب Xinyou Ma (3697816)

"…Herein, excess proton confinement effects are computationally investigated for sub-2 nm hydrophobic nanopores by varying the diameters (<i>d</i> = 0.81, 0.95, 1.09, 1.22, 1.36, 1.63, and 1.90 nm), lengths (<i>l</i> ∼3 and ∼5 nm), curvature, and chirality of cylindrical carbon nanotube (CNT) nanopores. …"

Water-Assisted Proton Transport in Confined Nanochannels حسب Xinyou Ma (3697816)

"…Herein, excess proton confinement effects are computationally investigated for sub-2 nm hydrophobic nanopores by varying the diameters (<i>d</i> = 0.81, 0.95, 1.09, 1.22, 1.36, 1.63, and 1.90 nm), lengths (<i>l</i> ∼3 and ∼5 nm), curvature, and chirality of cylindrical carbon nanotube (CNT) nanopores. …"

Water-Assisted Proton Transport in Confined Nanochannels حسب Xinyou Ma (3697816)

"…Herein, excess proton confinement effects are computationally investigated for sub-2 nm hydrophobic nanopores by varying the diameters (<i>d</i> = 0.81, 0.95, 1.09, 1.22, 1.36, 1.63, and 1.90 nm), lengths (<i>l</i> ∼3 and ∼5 nm), curvature, and chirality of cylindrical carbon nanotube (CNT) nanopores. …"