Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades حسب Ihab Shawish (13015516)

الموضوعات:

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades حسب Ihab Shawish (13015516)

الموضوعات:

Expression of ApoB-50 decreased lipid accumulation and inhibited HCV production. حسب Bei Wang (116772)

Effect of melatonin (50 μM) on the TGF-β1 (10 ng/mL, 72 h)-mediated TGF-β1/Smad pathway and EMT in HBdSMCs. حسب Yang Zhang (30734)

Tax expression is associated with decreased cellular motility. حسب Saumya Ramanayake (7879091)

Transcriptional and translational markers of syncytialization and biochemical differentiation are significantly decreased by rotenone. حسب O’Llenecia S. Walker (8486163)

HFD induces LDs and decreases ER and mitochondria in nephrocytes. حسب Aleksandra Lubojemska (10746241)

"…(<b>E</b>) Low and high magnification views of pericardial nephrocytes (dotted outlines) from STD and HFD larvae, showing that HFD decreases mitochondria (marked with anti-ATP5A) and ER (marked with anti-KDEL) but increases LDs (marked with LipidTOX). …"

IODVA1 inhibits lamellipodia and circular dorsal ruffle (CDR) formation in MDA-MB-231 cells and decreases Rac activation. حسب Anjelika Gasilina (8566296)

Passive transfer of humanized anti-NS1 mAb 33D2 into DENV-inoculated mice decreases viral titer and NS1 level in mouse sera. حسب Sen-Mao Tien (12481273)

SARS-CoV-2 inhibits SG formation and decreases expression of G3BP1. حسب Stacia M. Dolliver (13822801)

The GluN2B-C456Y mutation decreases recombinant NMDAR currents and alters receptor properties. حسب Wangyong Shin (6793040)

"…<i>n</i> = 73 oocytes for WT (5.70 ± 0.61 μA) and 59 oocytes for C456Y (0.039 ± 0.004 μA), ***<i>P</i> < 0.001, Mann-Whitney. …"

Conditional ablation of <i>Ybx1</i> leads to a reduction in cortical progenitor cell pool and a decrease in cortical thickness. حسب Jian Zhang (1682)

Dose response of airways to Methacholine shows a decreased contractility in <i>GSTCD</i>^-/- mouse lungs following LPS treatment. حسب Bo Liu (127343)

EGFR/ERK signaling activity decreases throughout LEC elimination with endocytic activity dependency. حسب Kevin Yuswan (19845885)

Exposure to low CO₂ levels decreases ER cholesterol levels. حسب Nityanand Bolshette (17396845)

"…<b>(F)</b> qPCR analysis for cholesterogenic genes from NIH3T3 cells exposed to cholesterol (50 μm) or 25-hydroxycholesterol (10 μm) under 5% or 1% CO₂ for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, ***<i>P</i> < 0.001, nonsignificant (ns), two-way ANOVA with Bonferroni’s multiple comparisons test). …"

Decrease in vRNA in brain during antiretroviral therapy. حسب Sonny R. Elizaldi (9684796)

Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant حسب Ittipat Meewan (7455041)

"…However, in the same assay, the potency of the approved drug, simeprevir, decreased 5.7-fold for the mutant enzyme relative to the wild type. …"

pDNA-PK levels are decreased in absence of cGAS. حسب Elona Gusho (4688170)

The effect of alexidine, amorolfine and olorofim on <i>S</i>. <i>aurantiacum</i> morphology and cell parameters. حسب Rodrigo Rollin-Pinheiro (239450)

الموضوعات:

AIM-100 reduces dsRNA silencing in body wall muscle and decreases DA neurodegeneration. حسب Anthony L. Gaeta (13272609)