VPS34 inhibition decreases intracellular levels of cholesteryl-esters, blocks cholesterol uptake and enhances lysosomal degradation of LDLR. by Marek J. Kobylarz (9292599)

Ifit2 deficiency results in decreased neuroinflammation upon RSA59 infection. by Jayasri Das Sarma (652473)

Repeat peptide stimulated CD8+ T cells have decreased cytotoxic function. by Manzhi Zhao (9023381)

Model performance according to number of variables by 5-fold cross-validation. by Gazi Md. Salahuddin Mamun (13905678)

Subjects:

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(C)</b> Total cholesterol quantification (with fluorometric assay kit) in NIH3T3 cells depleted with sterols for 2 h or exposed to different CO₂ levels for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, **<i>P</i> < 0.01, nonsignificant (ns), two-sided Student’s <i>t</i> test). <b>(D, E)</b> The free cholesterol and cholesterol ester levels in the ER membrane from the cells as in <b>(C)</b>, were quantified with shotgun lipidomics analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s007" target="_blank">S7 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s012" target="_blank">S5 Table</a>) (mean ± SE, <i>n</i> = 3 independent experiments, **<i>P</i> < 0.01, *<i>P</i> < 0.05, nonsignificant (ns) two-sided Student’s <i>t</i> test). …”

CR increases ROS and decreases the mtDNA copy number in MLH1 deficient cells. by Berna Somuncu (12770334)

Decreased hyper-resection in a NuA4 acetylation defective mutant in G1 and defect in DNA break repair by SSA. by Salar Ahmad (11457776)

“…Yeast strains used had similar HO cutting efficiency (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009816#pgen.1009816.s005" target="_blank">S5C Fig</a>). (E) The sensitivity of the <i>esa1-ts</i> mutant cells to DNA damage is partially suppressed by deletion of core NHEJ factors. 10-fold serial dilution spot assays were performed with <i>esa1-L254P</i>, <i>rad9</i>Δy<i>ku80</i>Δ and <i>rad9</i>Δy<i>ku80</i>Δ<i>esa1-L254P</i> cells in the absence or the presence of DNA damaging agent MMS. …”

The transcript and protein abundances of several VAC-residing proteases were decreased in Δ<i>crt</i>. by L. Brock Thornton (6808385)

Table_1_A glossy mutant in onion (Allium cepa L.) shows decreased expression of wax biosynthesis genes.xlsx by Tushar Kashinath Manape (16871172)

DataSheet_1_A glossy mutant in onion (Allium cepa L.) shows decreased expression of wax biosynthesis genes.docx by Tushar Kashinath Manape (16871172)

Maximum decreases in minute ventilation after fentanyl bolus administration (%). by Laurence M. Moss (12009078)

The GluN2B-C456Y mutation decreases recombinant NMDAR currents and alters receptor properties. by Wangyong Shin (6793040)

“…<p>(A) The GluN2B-C456Y mutation strongly decreases diheteromeric GluN1/GluN2B NMDAR currents in <i>Xenopus</i> oocytes. …”

Ifit2 deficiency decreases CX3CR1 expression in microglia following infection. by Jayasri Das Sarma (652473)

Table 1_Effect of decreased suspended sediment content on chlorophyll-a in Dongting Lake, China.docx by Le Zhang (88249)

A summary of conditions with decreased RRs (frequentist, US all-patient). by Hanxin Zhang (4280524)

Maximum IFN concentrations are decreased in severe patients. by Sonia T. Gazeau (21512764)

Decreased brain-derived neurotrophic factor plasma levels in psoriasis patients by A.R. Brunoni (5694239)

Firing rate decreases during rule-based decisions. by R. Becket Ebitz (7841318)

Tom clone number and area decrease during pupariation. by Jeremy Brown (3311742)

COG annotation of differentially abundant proteins of three genotypes of <i>Lolium perenne</i> (fold increase>1.5, fold decrease<0.5, <i>P</i> < 0.05). by Fatemeh Raeisi Vanani (8991491)