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  1. 1
    Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.

    Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. by P, Sneha

    Published 2018
    “…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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  2. 2
    Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach

    Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach by P., Sneha

    Published 2017
    “…Triplicate runs of molecular dynamic (MD) simulations (50ns) revealed smaller changes in patterns of deviation, fluctuation, and compactness, in complexes containing the R131Q and R131W mutations, compared to complexes containing the R203C mutant complex. …”
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