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50 point » 5 point (Expand Search), _ point (Expand Search), a point (Expand Search)
point decrease » point increase (Expand Search)
wt decrease » _ decrease (Expand Search), nn decrease (Expand Search), awd decreased (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), mean decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
50 point » 5 point (Expand Search), _ point (Expand Search), a point (Expand Search)
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Image_2_SIRT1 haplo-insufficiency results in reduced cortical bone thickness, increased porosity and decreased estrogen receptor alpha in bone in adult 129/Sv female mice.tif
Published 2022“…</p>Methods<p>To investigate the mechanisms of gender differences in SIRT1 skeletal effect, we investigated femoral and vertebral cortical and cancellous bone in global Sirt1 haplo-insufficient 129/Sv mice aged 2,7,12 months lacking Sirt1 exons 5,6,7 (Sirt1<sup>+/Δ</sup>) and their wild type (WT) counterparts.…”
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805
Image_1_SIRT1 haplo-insufficiency results in reduced cortical bone thickness, increased porosity and decreased estrogen receptor alpha in bone in adult 129/Sv female mice.tif
Published 2022“…</p>Methods<p>To investigate the mechanisms of gender differences in SIRT1 skeletal effect, we investigated femoral and vertebral cortical and cancellous bone in global Sirt1 haplo-insufficient 129/Sv mice aged 2,7,12 months lacking Sirt1 exons 5,6,7 (Sirt1<sup>+/Δ</sup>) and their wild type (WT) counterparts.…”
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806
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807
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CD43<sup>-/-</sup> septic mice exhibit decreased frequencies of apoptotic CD4<sup>+</sup> and CD8<sup>+</sup> naïve T cells as compared to WT septic mice.
Published 2018“…B) CD43<sup>-/-</sup> septic mice exhibited a decreased frequency of apoptotic naïve CD4<sup>+</sup> T cells, defined as 7-AAD<sup>+</sup> Annexin V<sup>+</sup> CD44<sup>LO</sup> CD62L<sup>HI</sup> CD4<sup>+</sup> cells, compared to WT septic mice (11.8±1.6 vs 18.8±1.3, p = 0.002. …”
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810
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811
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812
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813
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814
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815
The Type 2 Diabetes Risk Allele of <i>TMEM154</i>-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes
Published 2015“…Significant associations between <i>TMEM154</i>-rs6813195 and the beta cell measures insulinogenic index and disposition index and between <i>FAF1</i>-rs17106184 and 2-hour serum insulin levels were selected for further investigation in additional Danish studies and results were combined in meta-analyses including up to 6,486 Danes.</p><p>Results</p><p>We confirmed associations with type 2 diabetes for five of the seven SNPs (<i>TMEM154</i>-rs6813195, <i>FAF1</i>-rs17106184, <i>POU5F1/TCF19</i>-rs3130501, <i>ARL15</i>-rs702634 and <i>ABCB9/MPHOSPH9</i>-rs4275659). …”
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816
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817
DataSheet2_Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5−/− mice, decreases plasma cholesterol and epididymal fat deposition.pdf
Published 2022“…<p>We previously showed that Fmo5<sup>−/−</sup> mice exhibit a lean phenotype and slower metabolic ageing. …”
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818
DataSheet1_Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5−/− mice, decreases plasma cholesterol and epididymal fat deposition.PDF
Published 2022“…<p>We previously showed that Fmo5<sup>−/−</sup> mice exhibit a lean phenotype and slower metabolic ageing. …”
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819
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820
Loss of primary cilia and decreased nephron number in mice with Tamoxifen-induced <i>Kif3a</i> deficiency.
Published 2013“…(B, B’) KIF3A co-localizes with α-AcT in both ureteric bud and metanephric mesenchyme cells in WT kidney at E13.5. …”