Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein inter... حسب Thirumal Kumar, D.

"…From the analysis, we observed the highest deviation with lowest compactness and a decrease in the intramolecular h-bonds in the BRCA1-BARD1 protein complex with the V11G mutation compared to the native complex or the complexes with other mutations. 2022 Elsevier Inc.…"
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Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. حسب P, Sneha

"…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …"
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Smoking cessation counseling in Qatar: Community pharmacists' attitudes, role perceptions and practices حسب El Hajj, Maguy Saffouh

"…Main outcome measures: Qatar community pharmacists' smoking cessation practices, their attitudes toward tobacco use, smoking cessation and smoking cessation counseling and their perceived barriers for smoking cessation counseling. Results: Over 5 months, we collected 127 surveys (40 % response rate). …"
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The Structure of the Free Volume in Poly(styrene-co-acrylonitrile) from Positron Lifetime and Pressure Volume Temperature (PVT) Experiments حسب Dlubek, Gunter

"…The mean hole volume, vh, varies in PS between 105 Å3 (27 °C) and 220 Å3 (190 °C), and shows a systematic decrease with increasing AN content, at Tg from 121 Å3 for PS to 102 (±2) Å3 for SAN50. …"
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Origanum Syriacum Inhibits Proliferation, Migration, Invasion and Induces Differentiation of Human Aortic Smooth Muscle Cells حسب AlDisi, Sara

"…Cardiovascular diseases (CVDs) are still the number one cause of morbidity and mortality both in Qatar and worldwide. A major risk factor of CVDs is atherosclerosis, the hardening of blood vessels caused by decreased diameter and formation of plaque. …"
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Understanding the progress and challenges in the fields of thermo-catalysis and electro-catalysis for the CO2 conversion to fuels حسب Yadav, V. S. K.

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Global Consumption Trend of Antifungal Agents in Humans From 2008 to 2018: Data From 65 Middle- and High-Income Countries حسب Pathadka, Swathi

"…Consumption of ketoconazole slowly declined, with 5.04% annual decrease, probably due to labelling changes in 2013 to reflect hepatotoxicity concerns. …"
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Pd nanocrystals encapsulated in MOF-derived Ni/N-doped hollow carbon nanosheets for efficient thermal CO oxidation: unveiling the effect of porosity حسب Ipadeola, Adewale K.

"…This is evidenced in the great ability of Pd/Ni-MOF-HNC to utterly oxidize CO at a lower complete conversion temperature (T100) of 114.5 °C compared with Pd/Ni-MOF-NC (153.8 °C) and Pd/C (201.5 °C) under atmospheric pressure. …"
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STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS حسب AL-SADEQ, DUAA WALID

"…This study investigates the impact of five pathogenic CBS missense mutations [c.1006C>T (p.R336C), c.689T>A (p.L230Q), 215A>T (p.K72I), c.707C>A (p.T236N), and c.457G>A (p.G153R)] identified in homocystinuria patients and appeared to be resistant to pyridoxine treatment on the biochemical and biophysical properties of CBS protein. …"
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Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics حسب Nomikos, Michail

"…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …"
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Development of CuAg/Cu2O nanoparticles on carbon nitride surface for methanol oxidation and selective conversion of carbon dioxide into formate حسب Nazir, Roshan

"…Herein we report a catalyst consisting of CuAg/Cu2O nanoparticles (NPs), synthesized on the two-dimensional carbon nitride (CN) surface via galvanic exchange route for electrocatalytic methanol oxidation and carbon dioxide reduction. …"
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Hydrogen Production via Ethanol Decomposition over Bimetallic Catalyst حسب Ashok, Anchu

"…Once it reaches the ignition temperature, the combustion reaction started locally at one point and then spread inside the beaker. The resulted powder was grinded using a mortar and pestle to get a uniform powder to be used for catalytic investigations. …"
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Flight Scheduling in the Airspace حسب Msakni, Mohamed Kais

"…In this study, we developed a scatter search (SS) to deal with larger instances. …"
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Effect of Magnetic Baffles and Magnetic Nanofluid on Thermo-Hydraulic Characteristics of Dimple Mini Channel for Thermal Energy Applications حسب Souayeh, Basma

"…The increment changed to 1.82%, 8.16%, and 22.31% for a pitch = 5 mm and 1.01%, 5.96%, and 21.38% for a pitch = 2.5 mm. …"
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Effects of Climate and Atmospheric Nitrogen Deposition on Early to Mid-Term Stage Litter Decomposition Across Biomes حسب Kwon, Taeoh

"…We assessed how macroclimate and atmospheric inorganic N deposition under current and predicted scenarios (RCP 2.6, RCP 8.5) might affect litter mass loss measured after 3 and 12 months. …"
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Association between Insulin and Nitric Oxide in Human Retinal Microvascular Endothelial Cells in vitro حسب Rizk, Nasser Moustafa

"…This study demonstrated that hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis. eNOS mediated NO production increases with hyperglycemia but remarkably decreases with insulin treatment after 1 hour, 2 hours and 4 hours. …"
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Emerging clay-aryl-gold nanohybrids for efficient electrocatalytic proton reduction حسب Jlassi, Khouloud

"…Both nanohybrids showed efficient electrochemical activity for HER in acidic condition (0.1 M H2SO4) with high current density up to −25 mA.cm−2 at −1 V and 0.148 mV onset. Negligible decreasing in current density and slight shift in onset was observed after 1000 cycles. …"
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Thermal and mechanical characterization of injection moulded high density polyethylene/paraffin wax blends as phase change materials حسب Sotomayor, M.E.

"…The blends were prepared from 5 to 50vol. % of paraffin wax employing a twin-screw extruder. …"
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Biodegradable thermoplastic polyurethane composites as potential plating systems in pediatric facial fractures حسب ALANI, AYA AHMED

"…The H12MDI based thermoplastic polyurethane was prepared using 12% HS 50:50 BD-Poly D, L-lactide -co-glycolide, then the composites were prepared by the addition of 3 and 15% of hydroxyapatite, respectively. …"
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Effect of outdoor temperature on the power-conversion efficiency of newly synthesized organic photosensitizer based dye-sensitized solar cells حسب Mehmood U.

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