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AMPK Activation Attenuates Albumin-induced Alterations in Renal Tubular Cells In Vitro
Published 2016“…Notably, metformin also prevented albumin-induced EMT; this was marked by a 50% decrease in a-SMA and a 60% increase in E-cadherin expression. …”
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383
Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2.
Published 2018“…The D-2-HGA includes two subtypes: type I and type II caused by the mutations in D2HGDH and IDH2 proteins, respectively. In this study, we studied six mutations, four in the D2HGDH (I147S, D375Y, N439D, and V444A) and two in the IDH2 proteins (R140G, R140Q). …”
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384
Overconfident results with the bivariate random effects model for meta-analysis of diagnostic accuracy studies
Published 2022“…Diaz found that the performance of the bivariate model deteriorates when between-study heterogeneity increases and the number of studies decrease.5 Our simulation studies found similar results—with moderate levels of heterogeneity (tau2 = 1), the coverage probabilities of Se, Sp, and the diagnostic odds ratio (DOR) with the bivariate model dropped below the nominal level.6 Diagnostic accuracy studies usually favor sensitivity over specificity, or vice versa leading to diagnostic 2 × 2 tables with one or more of the cells with low frequency or zero counts. …”
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385
Effect of hyperglycemia on EPCs function and regenerative ability
Published 2020“…This research aims to test the EPC subtype blood outgrowth endothelial cells (BOECs) and their ability to survive and function under chronic hyperglycemic conditions. For that, we studied BOECs viability, response to shear stress, angiogenesis ability, and barrier function under normoglycemic (5.5mM) and hyperglycemic (25mM) conditions. …”
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386
Investigating the utilization of healthcare services to manage respiratory tract infections (RTIs) among Qatari patients attended selected primary healthcare centers in Qatar
Published 2018“…We have found no difference in the month-to-month rates of RTI-related GP visits (per 1000 total visits) over the study period (non-significant decreasing trend). …”
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387
Correlation between delta-endotoxin and proteolytic activities produced by Bacillus thuringiensis var. kurstaki growing in an economic production medium
Published 2013“…Maximal protease activity (540-2468 UI) obtained by BUPM5-1 and BUPM5-2 was 2.34-fold and 10.7-fold, respectively, more than that obtained by the wild strain BUPM5 with a drastic decrease of their delta-endotoxin production. …”
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388
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389
Superior photocatalytic activity of Cu doped NiWO4 for efficient degradation of benzene in air even under visible radiation
Published 2019“…This was because Cu effectively acted as novel dopant, which not only affected valence band (VB) top and conduction band (CB) bottom of NiWO4 but also formed a medium energy level between CB and VB of the NiWO4 to decrease its energy band gap and electron-hole recombination rate. …”
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390
Trends in prevalence of depression and anxiety symptoms and effects of sociodemographic variables before and after the first wave of COVID-19 in Qatar
Published 2022“…The data for 2020/21 showed a 35.1% and 29.2% decrease in depression and anxiety symptoms scores compared to pre-pandemic years (2017/2018) after adjusting for sociodemographic factors. …”
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391
Roadmap toward energy-positive upfront nitrogen removal process in baseload LNG plant
Published 2022“…The results show that UNrem of 87.5% from the NG feed can reduce the total power requirements by 0.24%, increase the production flow rate by 4.4%, and decrease the exergy losses by 0.23% compared with the base case. …”
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392
Improvement of both lipid and biomass productivities of Qatar Chlorocystis isolate for biodiesel production and food security
Published 2018“…Most previous research evidenced that the increase of the lipid content is accompanied by a decrease of the biomass production, which increases the cost of the downstream processing. …”
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393
Antibiotic Prescription Patterns for Upper Respiratory Tract Infections in Outpatient Qatari Population in the Private Sector
Published 2016“…During the study period, health insurance was limited to Qatari nationals. We excluded topical antibiotics. We also retrieved data on prescriber’s specialty as listed with the licensing authority. …”
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394
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Effect of mobile text messages on antiretroviral medication adherence and patient retention in early HIV care: An open-label, randomized, single center study in south Florida
Published 2020“…Background People with HIV (PHIV) with limited access to health services often experience suboptimal antiretroviral therapy (ART) adherence. We investigated whether a daily text messaging intervention improves ART adherence and retention in early HIV care in PHIV in a south Florida hospital-based clinic. …”
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396
CLINICAL AND ECONOMIC IMPACT OF GENETIC AND NON-GENETIC FACTORS ON INR NORMALIZATION IN PRE-OPERATIVE MANAGEMENT OF WARFARIN PATIENTS
Published 2021“…To optimize the period of preprocedural warfarin interruption to decrease the incidence of bleeding in case of bridging and the incidence of thromboembolism in case of non-bridging, a study was conducted to determine the influence of CYP2C9, VKORC1, CYP4F2, FII, and FVII genetic polymorphisms and non-genetic factors on INR decline in a cohort of Arabs undergoing a procedure that requires warfarin interruption and developing an algorithm to tailor the duration of warfarin interruption before the procedure. …”
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397
Integrated planning of spare parts and service engineers with partial backlogging
Published 2017“…In a numerical study, we show that for problems with more than five types of spare parts it is preferable to use approximate evaluations as they become significantly faster than exact evaluation. …”
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398
Evacuated tube heat pipe solar collector for Encontech engine-driven reverse osmosis solar desalination
Published 2020“…Both energetic and exergetic efficiencies exhibit upper values at A co/A abs ratio up to 1. Further increment in this ratio up to 3 resulted in a decrease in the efficiency of the ETHPSC.…”
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399
Pharmacologic inhibition of hypoxia-inducible factor (HIF)-hydroxylases ameliorates allergic contact dermatitis
Published 2019“…Background When an immune cell migrates from the bloodstream to a site of chronic inflammation, it experiences a profound decrease in microenvironmental oxygen levels leading to a state of cellular hypoxia. …”
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400
Association between Insulin and Nitric Oxide in Human Retinal Microvascular Endothelial Cells in vitro
Published 2016“…This study demonstrated that hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis. eNOS mediated NO production increases with hyperglycemia but remarkably decreases with insulin treatment after 1 hour, 2 hours and 4 hours. …”
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