Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments by Gunjan Dagar (9339276)

“…Despite success in blood cancers, CAR-T technology faces challenges in solid tumors, including lack of reliable tumor-associated antigens, hypoxic cores, immunosuppressive tumor environments, enhanced reactive oxygen species, and decreased T-cell infiltration. …”

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

BRET-based biosensors for SARS-CoV-2 oligonucleotide detection by Asfia Sultana (19170880)

“…Specifically, we designed BioODs against the SARS-CoV-2 parental (Wuhan strain) and B.1.617.2 Delta variant through the conjugation of specific, fluorescently modified molecular beacons (sensor module) through a complementary oligonucleotide handle DNA functionalized with the NanoLuc (NLuc) luciferase protein such that the dissolution of the molecular beacon loop upon the binding of the viral oligonucleotide will result in a decrease in BRET efficiency and, thus, a change in the bioluminescence spectra. …”

A robust experimental-based artificial neural network approach for photovoltaic maximum power point identification considering electrical, thermal and meteorological impact by Samer Gowid (15955152)

“…The results showed a decrease in the MSE of V_mp by 74.3% (from 1.6 V to 0.411 V), and in the MSE of I_mp by 95% (from 4.4e−6 A to 2.16e−7 A), respectively. …”

Effect of Hypoxia on Maximal Fat Oxidation Rate During Incremental Cycling : Relationship to the Gas Exchange Threshold by Youmna Elsayed Hassanein (21547490)

“…The aim of this study was to evaluate MFO in normoxia (NORM) and hypoxia (HYPO) during exercise at intensities matched relative to the respiratory compensation point (RCP).</p><h3>Methods</h3><p dir="ltr">Seventeen recreationally active adults (5 females/12 males; age: 36.2 ± 7.4 year; body mass: 76.6 ± 13.1 kg) performed a ramp and a step incremental test, in NORM (The fraction of inspired oxygen; FiO₂ ≈ 21%) and HYPO (FiO₂ ≈ 13.5%), on separate days. …”

Shared Clean Mobility Operations for First-Mile and Last-Mile Public Transit Connections: A Case Study of Doha, Qatar by Afnan Fayez Eliyan (19517221)

“…A previous research mainly focused on car-sharing services as a self-standing mode of transportation. …”

Sleeve Gastrectomy in Patients with Type 2 Diabetes: Anthropometric and Cardiometabolic Improvements at 1, 3, 5, 7, and 9 years—Are the Initial Benefits Sustained? by Wahiba Elhag (5245547)

“…Fasting blood glucose decreased significantly across the five time points, from 9.27 ± 4.11preop to 7.06 ± 2.70 _year9mmol/L. …”

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…”
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Nonlinear Control of Brushless Dual-Fed Induction Generator With a Flywheel Energy Storage System for Improved System Performance by Mohammed Hamidat (3722086)

“…After optimization, the SMC settling time was significantly reduced from 0.7 seconds to 19.97 milliseconds, achieving a 96.9% improvement in response speed, while its steady-state error decreased from 0.48 to 0.06, marking an 87.5% reduction in tracking error. …”

Anti-angiogenic effect of nano-formulated water soluble kaempferol and combretastatin in an in vivo chick chorioallantoic membrane model and HUVEC cells by Gowtham Kumar Subbaraj (17807615)

“…Morphometric analysis of CAM showed that treatment with nano-formulated water-soluble kaempferol and combretastatin caused a substantial decrease in density, vessel network, branch points, and nets of CAM blood vessels. …”

Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function by Sahar I. Da'as (17128747)

“…Furthermore, circular dichroism spectroscopy experiments using recombinant CaM proteins reveals a decreased structural stability of the four mutants compared to the wild‐type CaM protein in the presence of Ca²⁺. …”

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma by Peter Kubatka (11008854)

“…In treated rat carcinomas, we found significant caspase-3, Bax, and Bax/Bcl-2 expression increases; on the other side, a significant down-regulation of Bcl-2, Ki67, CD24, ALDH1, and EpCam expressions and MDA levels. When compared to control specimens, evaluation of epigenetic alterations in rat tumor cells in vivo showed significant dose-dependent decrease in lysine methylation status of H3K4m3 and H3K9m3 and dose-dependent increase in lysine acetylation in H4K16ac levels (H4K20m3 was not changed) in treated groups. …”

Data-Efficient Wheat Disease Detection Using Shifted Window Transformer: Enhancing Accuracy, Sustainability, and Global Food Security by Muhammad Khubaib (22927822)

“…To enhance interpretability, Grad-CAM visualization techniques were applied, confirming model reliability. …”

BRET-Based Biosensors for Nucleic Acid Detection and Impact of Molecular Crowding Monitoring by Asfia Sultana (19170880)

“…<p dir="ltr">The advancement of biosensor technology and the demand for point-of-care diagnostics have driven the development of diverse methods for detecting viral infections and understanding complex biochemical processes. …”

Characterizing the dynamics of climate and native desert plants in Qatar by Meshal Abdullah (17746950)

“…However, the probability of rainfall events over 80 mm was less than 5%, while low rainfall seasons (1–17 mm) were more likely (90–99% chance). …”

Retinal imaging based glaucoma detection using modified pelican optimization based extreme learning machine by Debendra Muduli (20748758)

“…Furthermore, we have utilized seven Explainable AI methodologies: Vanilla Gradients (VG), Guided Backpropagation (GBP ), Integrated Gradients ( IG), Guided Integrated Gradients (GIG), SmoothGrad, Gradient-weighted Class Activation Mapping (GCAM), and Guided Grad-CAM (GGCAM) for interpretability examination, aiding in the advancement of dependable and credible automation of healthcare detection of glaucoma.…”

Generalized and pregnancy-related anxiety prevalence and predictors among pregnant women attending primary health care in Qatar, 2018–2019 by Sarah Naja (9954737)

“…</p><h3>Limitations</h3><p dir="ltr">There is no recognized optimal cut-off point to distinguish ‘high risk’ in pregnancy-related anxiety scales.…”

Effect of Hypoxia on Muscle Activation During Incremental Exercise at Equivalent Relative Intensity by Dania Nazeeh Ibrahim (21547487)

“…</p><h3>Methods</h3><p dir="ltr">Seventeen healthy active adults, male and female, with a background in cycling, completed a ramp and step incremental exercise testing in normoxia (NORM; FiO₂≈21%) and hypoxia (HYPO; FiO₂≈13.5%) on four occasions. Both ramp tests determined the respiratory compensation point (RCP) and gas exchange threshold (GET). …”

Assessment of resin systems as solution for well integrity challenge in carbonate reservoirs by Albertus Retnanto (17269237)

“…Additionally, the transit time showed a 26–42% range decrease in the travel period, indicating that the cement was stronger under increased pressure and temperature. …”

High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i... by Samar, Shurbaji

“…These key performance indicators were slightly decreased when fingerstick whole-blood samples were used: sensitivity [85.7 %(63.7–97)], specificity [90.0 %,(81.5–96)], good agreement (Cohen's Kappa = 0.7) and very strong correlation (r = 0.9, p < 0.0001) with cobas® e 601. …”
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