Modulation of SLFN11 induces changes in DNA Damage response in breast cancer by Christophe Michel Raynaud (17449906)

“…We then used the modified cell lines to quantify the alteration in chemo sensitivity of those cells to treatment with DNA Damaging Agents (DDAs) such as Cisplatin and Epirubicin or DNA Damage Response (DDRs) drugs like Olaparib. …”

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

A robust experimental-based artificial neural network approach for photovoltaic maximum power point identification considering electrical, thermal and meteorological impact by Samer Gowid (15955152)

“…<p dir="ltr">This paper aims to develop a robust and practical photovoltaic (PV) Maximum Power Point (MPP) identification tool developed using reliable experimental data sets. …”

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

Cost-benefit analysis of antimicrobial stewardship program in a cancer setting in Qatar by Dina Abushanab (10696501)

“…Cost avoidance was the expenses saved due to decreased hospital stays and fewer adverse drug events (ADEs). …”

Cost-Benefit Analysis of Antimicrobial Stewardship Program in the Adult General Medicine Setting in Qatar by Dina Abushanab (10696501)

“…</p><h3> Results</h3><p dir="ltr">The operational costs of the program decreased with maturity by cost savings of QAR125 per 100-patient beds per year. …”

The cost associated with the development of the antimicrobial stewardship program in the adult general medicine setting in Qatar by Dina Abushanab (10696501)

“…</p><h3>Results</h3><p dir="ltr">A total of 500 patients were included in the study. The operational costs decreased with the developed ASP. Whereas antimicrobial consumption and resource utilisation, and their associated costs, appear to have declined with the developed ASP, with a cost saving of QAR458 (US$125) per 100-patient beds, the avoided cost was negative, by QAR4,807 (US$1,317) per 100-patient beds, adding to a total QAR4,224 (US$1,160) increase in the 100-patient beds cost after ASP development.…”

Stochastic Programming for Hub Energy Management Considering Uncertainty Using Two-Point Estimate Method and Optimization Algorithm by Ali S. Alghamdi (17541711)

“…This has been done using a new meta-heuristic algorithm, improved artificial rabbits optimization (IARO). …”

The ortholog of human ssDNA-binding protein SSBP3 influences neurodevelopment and autism-like behaviors in <i>Drosophila melanogaster</i> by Safa Salim (9186786)

“…One such gene is the single-stranded DNA-binding protein 3 (<i>SSBP3</i>) and its Drosophila melanogaster ortholog is called sequence-specific single-stranded DNA-binding protein (<i>Ssdp</i>). …”

The cost-benefit associated with the maturity of the Antimicrobial Stewardship Program versus prematurity in Heart Hospital of Hamad Medical Corporation in Qatar by Dina Abushanab (10696501)

“…</p><h3>Results</h3><p dir="ltr">A total of 668 patients were included in the study (255 in P-ASP versus 413 in M-ASP). With M-ASP, cost of hospital tests use ‘decreased’ by QAR 1,149 per 100-patient beds per year, cost of ASP personnel ‘decreased’ by QAR 125 per 100-patient beds with the M-ASP, cost of drug use ‘increased’ by QAR 176,848 per 100-patient beds, cost of resistance and hospitalization ‘increased’ by QAR 216,279 per 100-patient beds per year. …”

Effect of Hypoxia on Maximal Fat Oxidation Rate During Incremental Cycling : Relationship to the Gas Exchange Threshold by Youmna Elsayed Hassanein (21547490)

“…A 25% decrease in MFO in HYPO (0.25 ± 0.08g.min^-1) compared to NORM (0.35 ± 0.08g.min-1; <i>P</i> < 0.001; <i>d</i> =1.24) was observed. …”

The investigation of treatment design parameters on carbon integration networks by Sabla Y. Alnouri (6331652)

“…As a result, this paper focuses on reassessing the performance of carbon integration networks using a more rigorous cost model for the treatment design stage. The effect of utilizing different treatment operating conditions on the overall cost of the treatment stage of CO₂(before allocation) is first captured using a detailed cost model. …”

Nonlinear Control of Brushless Dual-Fed Induction Generator With a Flywheel Energy Storage System for Improved System Performance by Mohammed Hamidat (3722086)

“…After optimization, the SMC settling time was significantly reduced from 0.7 seconds to 19.97 milliseconds, achieving a 96.9% improvement in response speed, while its steady-state error decreased from 0.48 to 0.06, marking an 87.5% reduction in tracking error. …”

Infliximab versus ciclosporin in steroid resistant acute severe ulcerative colitis: a model-based cost-utility analysis of data from CONSTRUCT pragmatic trial by Mohammed Fasihul Alam (6832217)

“…<h3>Background</h3><p dir="ltr">There is limited evidence in the literature on the long-term effectiveness and cost-effectiveness of treatments for Acute Severe Ulcerative Colitis (ASUC). …”

An efficient claim management assurance system using EPC contract based on improved monarch butterfly optimization models by K. Mukilan (22224793)

“…Conventional construction models typically optimize only a single objective, such as time, cost, or delay, which may not effectively enhance overall performance. …”

Coalition game theoretic P2P trading in a distribution network integrity-ensured local energy market by M., Imran Azim

“…The simulation results confirm that participants, both sellers and purchasers, can decrease their energy costs substantially, and the LEM operator can also secure its margin while the distribution network voltages and line congestion are within the prescribed ranges.…”
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The effect of Ramadan focused education on patients with type 2 diabetes: A systematic review and meta-analysis by Hoda Gad (6470522)

“…It also identifies a lack of head to head studies and limited observational studies with adequately assessed end-points.…”

Enhancing the production of biogas through anaerobic co-digestion of agricultural waste and chemical pre-treatments by Fares Almomani (12585685)

Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity by Mohamed Abu-Farha (18535590)

Generalized and pregnancy-related anxiety prevalence and predictors among pregnant women attending primary health care in Qatar, 2018–2019 by Sarah Naja (9954737)

“…Tailored interventional studies could focus on increasing resilience and social support to decrease the burden of antenatal anxiety.</p><h2>Other Information</h2><p dir="ltr">Published in: Heliyon<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.heliyon.2020.e05264" target="_blank">https://dx.doi.org/10.1016/j.heliyon.2020.e05264</a></p>…”