Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs حسب Salam Salloum-Asfar (656363)

"…<div><p>Somatic cells are reprogrammed with reprogramming factors to generate induced pluripotent stem cells (iPSCs), offering a promising future for disease modeling and treatment by overcoming the limitations of embryonic stem cells. …"

Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity حسب Mohammed R. Shaker (10316180)

"…In this study, we utilised human induced pluripotent stem cells (iPSCs) engineered with a doxycycline-inducible system to overexpress <i>KLOTHO</i> and generated 2D cortical neuron cultures from these cells. …"

The Impact of COVID-19 on the HIV Cascade of Care in Botswana – An Interrupted Time Series حسب Alice Sehurutshi (21842696)

"…In multivariable Poisson interrupted time series regression, the COVID-19 lockdown was associated with a 27% decrease in the monthly numbers of HIV tests (IRR 0.73, 95%CI 0.72–0.73), a 25% decrease in HIV positive tests (IRR 0.75, 95%CI 0.71–0.79), and a 43% reduction in ART initiations (IRR 0.57, 95%CI 0.55–0.60). …"

A customised fetal growth and birthweight standard for Qatar: a population-based cohort study حسب Thomas Farrell (3933833)

"…</p><h3>Results</h3><p dir="ltr">The regression model found a term optimal birthweight of 3,235 g for a Qatari nationality mother with median height (159 cm), booking weight (72 kg), parity (1) and gestation at birth (276 days) at the end of an uncomplicated pregnancy. …"

Hepato‐splanchnic fluxes during exercise in patients with cirrhosis—a pilot study حسب Stefanos Volianitis (22155835)

"…</p><h2>Other Information</h2><p dir="ltr">Published in: Physiological Reports<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.14814/phy2.16162" target="_blank">https://dx.doi.org/10.14814/phy2.16162</a></p>…"

Predictors of mortality and morbidity in critically ill COVID‐19 patients: An experience from a low mortality country حسب Mohamad Y. Khatib (11659459)

"…The median (IQR) age of patients was 50 (41–59) years. …"

Clinical characteristics and outcome of children with acute cryptorchid testicular torsion: A single-center, retrospective case series study حسب Zlatan Zvizdic (9212371)

"…The median duration of symptoms was 16 h (IQR 9–25 h), while the median time to treatment was 60 min (IQR 59–63 min). …"

Mortality and socio-economic outcomes among patients hospitalized for stroke and diabetes in the US: a recent analysis from the National Inpatient Sample حسب Aya Tabbalat (14150019)

"…As expected, the average total charges per hospital stay almost doubled over the ten-year period, increasing from 15 970 to 31 018 USD/stay (adjusted for inflation). Nonetheless, median (IQR) LoS slightly decreased from 4 (2–6) to 3 (2–6) days (p-trend < 0.001). …"

Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample حسب Menatalla Mekhaimar (14103708)

"…Crude mortality gradually decreased from 2.7% in 2005 to 2.4% in 2014 but was still lower than that of non-diabetes patients’ mortality on a yearly comparison basis. …"

Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults حسب Nowell H, Phelps

"…FindingsFrom 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in 11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed changes were true decreases. …"
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Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis حسب Fateen Ata (12217764)

"…Patients with a 6-month DKA recurrence, female gender and T1DM had higher odds of 12-month recurrence, whereas a consult with a diabetes educator at the index admission was associated with decreased odds of recurrence.…"

Blockchain, climate damage, and death: Policy interventions to reduce the carbon emissions, mortality, and net-zero implications of non-fungible tokens and Bitcoin حسب Jon Truby (14153022)

"…<p dir="ltr">The art industry has commercialised and popularised non-fungible tokens (NFTs), with the volume and value of NFT transactions rapidly growing to US$ 10.7 billion in Q3 2021. …"

Investigating the Role of FOXA2 Transcription Factor in Adipogenesis Using Human-Induced Pluripotent Stem Cells حسب Hafsa Madni (22674428)

"…Therefore, in this study, we aimed to investigate the role of <i>FOXA2</i> in adipogenesis using previously established wild-type induced pluripotent stem cells (WT-iPSCs) and <i>FOXA2</i> knockout iPSCs (FOXA2 KO iPSCs). …"

Reinforced steering Evolutionary Markov Chain for high-dimensional feature selection حسب Atiq ur Rehman (3044409)

"…(v) The effective size of successful agents is reduced recursively while progressing through different states to further facilitate the speed of convergence and decrease the number of features. (vi) The performance comparison with state-of-the-art feature selection methods shows a significant improvement and promise of the proposed method over the existing methods.…"

Improving pediatric trauma care: an automated system for wrist trauma detection using GELAN حسب Promit Basak (22997776)

"…As a result, it achieves state-of-the-art performance in both trauma and severity detection. …"

Machine learning in crime prediction حسب Karabo Jenga (17788496)

"…In this paper, we evaluate state-of-the-art crime prediction techniques that are available in the last decade, discuss possible challenges, and provide a discussion about the future work that could be conducted in the field of crime prediction. …"

Assessment Tools for Pulmonary Involvement in Patients with Ankylosing Spondylitis: Is Diaphragmatic Ultrasonography Correlated to Spirometry? حسب Rim Dhahri (21406871)

"…</p><h3>Results</h3><p dir="ltr">The mean age of the study participants (N= 50) was 42.7± 11 years [range: 25– 66] with male predominance (N= 41). Spirometry showed a restrictive disorder in 32% of cases. The mean chest expansion (CE) value was 3.9± 1.81cm [range: 1– 9] with a median of 4 cm. …"

Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1⁺/NKX6.1⁺ progenitors حسب Noura Aldous (15429873)

"…Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …"

Data-Efficient Wheat Disease Detection Using Shifted Window Transformer: Enhancing Accuracy, Sustainability, and Global Food Security حسب Muhammad Khubaib (22927822)

"…<p dir="ltr">Wheat is an essential crop that plays a vital role in global food security, but is susceptible to a variety of diseases, which have the potential to drastically decrease crop productivity. Detection of disease at an early stage and in an accurate manner is crucial to minimize crop losses. …"

Assessment of treatment burden and its impact on quality of life in dialysis-dependent and pre-dialysis chronic kidney disease patients حسب Asmaa Al-mansouri (16931739)

"…HD patients experienced significantly higher treatment burden compared to pre-dialysis patients with a median (IQR) score of 45 (36) versus 25 (33), respectively (p < 0.001). …"