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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes
Published 2021“…</p><h2>Other information</h2><p dir="ltr">Published in: BMJ Open Diabetes Research and Care<br>License: <a href="http://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by-nc/4.0/</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1136/bmjdrc-2020-001925" target="_blank">http://dx.doi.org/10.1136/bmjdrc-2020-001925</a></p>…”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…</p><p> </p></div><h2>Other Information</h2> <p> Published in: International Journal of Molecular Sciences<br> License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/ijms20040844" target="_blank">https://dx.doi.org/10.3390/ijms20040844</a></p>…”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…</p><h2>Other Information</h2><p dir="ltr">Published in: Redox Biology<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.redox.2022.102574" target="_blank">https://dx.doi.org/10.1016/j.redox.2022.102574</a></p>…”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…</p><h2>Other Information</h2><p dir="ltr">Published in: Frontiers in Molecular Biosciences<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a></p>…”
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Basophil-VAMP7 is a vital regulator of skin barrier integrity and chronic itch
Published 2025“…VAMP7 knockout also decreased IL-4 and LTC4 release from basophils. Additionally, OSM downregulated barrier proteins and upregulated pruriceptors in keratinocytes; however, these effects were reversed by SC144, which restored skin barrier function in AIF without affecting itch response in either model. …”
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Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex
Published 2022“…<p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a>, published online 22 July 2022.…”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…</p><p> </p></div><h2>Other Information</h2> <p> Published in: Stem Cells International<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1155/2019/3041262" target="_blank">https://dx.doi.org/10.1155/2019/3041262</a></p>…”
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Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity
Published 2013“…HDAC4 could therefore represent a potential therapeutic target for the control and management of obesity and presumably insulin resistance.…”
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3D Concrete Printing Sustainability: A Comparative Life Cycle Assessment of Four Construction Method Scenarios
Published 2020“…The LCA was conducted for a 1 m2 external load-bearing wall in all four scenarios. …”
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Case report: Safety and efficacy of voxelotor in a patient with sickle cell disease and stage IV chronic kidney disease
Published 2022“…The data about the safety and efficacy of voxelotor use in chronic kidney disease is limited. Herein we report a 49-year-old man, with sickle cell disease and stage IV chronic kidney disease, who was managed successfully with voxelotor and resulted in decreasing transfusion requirement and vaso-occlusive painful crisis without affecting kidney function.…”
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eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
Published 2018“…Cytokines, including interferon γ (IFNγ), tumor necrosis factor α (TNFα) and interleukin-6 (IL-6), and their downstream effectors such as Signal Transducer and Activator of Transcription 3 (STAT3), have been shown to play a prominent role in muscle wasting. Previously, we demonstrated that Pateamine A (PatA), a compound that targets eukaryotic initiation factor 4A (eIF4A), could prevent muscle wasting by modulating the translation of the inducible Nitric Oxide Synthase (iNOS) mRNA. …”
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Preparation of Mesoporous/Microporous MnCo<sub>2</sub>O<sub>4</sub> and Nanocubic MnCr<sub>2</sub>O<sub>4</sub> Using a Single Step Solution Combustion Synthesis for Bifunction Oxy...
Published 2020“…A slightly larger crystallite size was observed for MnCr<sub>2</sub>O<sub>4</sub>. …”
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PGAP3 Associated with Hyperphosphatasia with Mental Retardation Plays a Novel Role in Brain Morphogenesis and Neuronal Wiring at Early Development
Published 2020“…<p dir="ltr">Recessive mutations in Post-GPI attachment to proteins 3 (PGAP3) cause the rare neurological disorder hyperphosphatasia with mental retardation syndrome 4 type (HPMRS4). Here, we report a novel homozygous nonsense mutation in PGAP3 (c.265C>T-p.Gln89*), in a 3-year-old boy with unique novel clinical features. …”
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Successful minimally invasive management of nonvascular grade IV blunt renal trauma with complete transection in a 7-year-old girl
Published 2022“…Although such injuries have a decreased likelihood of spontaneous resolution, not all require open operative repair. …”
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Performance comparison of different flow arrangements of 4-fluid internally-cooled liquid desiccant dehumidifiers
Published 2022“…</p><h2>Other Information</h2> <p> Published in: Journal of Thermal Analysis and Calorimetry<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s10973-022-11283-x" target="_blank">http://dx.doi.org/10.1007/s10973-022-11283-x</a></p>…”
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DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation
Published 2019“…Using JNK1- and IKKβ-dependent luciferase reporters, we show a marked decrease in luciferase activity by DNAJB3 in response to PMA and TNF-α that was consistent with a decrease in the translocation of p65/NF-κB to the nucleus in response to LPS. …”