Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications حسب Jingxuan Shan (4711089)

"…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. A decreased risk of lymph node metastasis was associated with the <b><i>MAP3K21</i></b><b> </b><b>rs1294255-C</b> allele, particularly in <b>rs1294255-GC</b> (OR = 0.47; <i>P</i> = 0.001). …"

Combined effects of treated domestic wastewater, fly ash, and calcium nitrite toward concrete sustainability حسب Abdelrahman Abushanab (17268940)

"…Test results revealed that TWW slightly decreased concrete compressive and flexural strengths by 5%–12%, whereas it dramatically increased the porosity and chloride permeability by about 40%. …"

Exploring beyond numeric weight loss: The metabolic effects of semaglutide حسب Sara Sokary (17337724)

"…Also, it enhanced glycemic control, as evidenced by significant reductions in hemoglobin A1C (HbA1c) with the 0.5 mg and 1.0 mg doses. From a baseline range of 8.1–8.7 %, 0.5 mg dose lowered HbA1c by 1.2–1.5 %, while the 1.0 mg dose reduced it by 1.4–1.8 %. …"

Impact of composition and salinity on swelling and gel strength of poly (acrylamide-co-acrylic acid) preformed particle gel حسب Ahmed Ben Ali (17792594)

"…The swelling ratios of the PPGs in brine 1 at 50 °C were between 12 and 32 g/g, having strengths in the range of 566–5508 Pa, depending on the crosslinker ratio. …"

Road safety and traffic medicine in Iran: Achievements and challenges حسب A. Motevalian (19807242)

"…Heavier penalties for major offences like: speeding, driving under the influence and dangerous driving are considered in the new law; b) stricter law enforcement by traffic polices(1); c) mass media campaign for traffic injury prevention (1); d) using fixed speed camera systems and laser speed guns; e) universal coverage of hospital treatment costs for all traffic injuries by Ministry of Health and Medical Education(2); and f) graduated driving license. …"

Investigating the structural impacts of a novel missense variant identified with whole exome sequencing in an Egyptian patient with propionic acidemia حسب Ali Zaki Ibrahim (17092957)

"…Computational analyses revealed that the novel variant might have a pathogenic effect that attributed to decreased protein stability, and also has an effect on the biotin carboxylase c-terminal domain of the propionyl carboxylase enzyme. …"

Energy conversion of heat from abandoned oil wells to mechanical refrigeration - Transient analysis and optimization حسب Mohammed Al-Khawaja (17093017)

"…Results show that at realistic and conservative conditions, the geofluid temperature considerably decreases for the first four months of operation (by an average of 30 °C) and tends to be constant after half a year of operation. …"

Control of the Speed of a Light-Induced Spin Transition through Mesoscale Core-Shell Architecture حسب Slimani, Ahmed

"…A series of photomagnetic coordination polymer core-shell heterostructures, based on the light-switchable RbaCob[Fe(CN)6]c·mH2O (RbCoFe-PBA) as core with the isostructural KjNik[Cr(CN)6]l·nH2O (KNiCr-PBA) as shell, are studied using temperature-dependent powder X-ray diffraction and SQUID magnetometry. …"
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Empirical evaluation of change in crash risk due to lane marking reallocation: A case study in Kochi City, Japan حسب Hiroaki, Nishiuchi

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Post-transcriptional regulation of Pabpn1 by the RNA binding protein HuR حسب Brittany L Phillips (18696937)

"…We exploit multiple models including C2C12 myotubes, primary muscle cells, and mice to determine that HuR decreases Pabpn1 expression. …"

Monitoring polycyclic aromatic hydrocarbons in the Northeast Aegean Sea using Posidonia oceanica seagrass and synthetic passive samplers حسب Pavlopoulos, Kosmas

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Engineering Novel Single-chain Variable Fragments for Therapeutic and Diagnostic Approaches in Parkinson's Disease حسب Safa Salim (9186786)

"…In this project, single-chain variable fragments (scFvs) were engineered against fibrillar α-synuclein. Six different scFv cDNA constructs, containing either cell-penetrating peptide (CPP), 12-Arginine, or no peptide, were cloned in <i>E. coli</i> expression constructs with or without GST tag. …"

Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials حسب Pieter Francsois, Fouche

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Inflammation-Modulating Biomedical Interventions for Diabetic Wound Healing: An Overview of Preclinical and Clinical Studies حسب Nouf N. Mahmoud (9133074)

"…Additionally, this review provides an overview of selected clinical studies employing biomaterials and bioactive molecules, shedding light on the gap between extensive preclinical research and limited clinical studies in this field.</p><h2>Other Information</h2><p dir="ltr">Published in: ACS Omega<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1021/acsomega.4c02251" target="_blank">https://dx.doi.org/10.1021/acsomega.4c02251</a></p>…"

Clinical and Biochemical Analysis of Glutamate-Cysteine Ligase Deficiency Presented with Late-Onset Spinocerebellar Ataxia and Hemolytic Anemia حسب Mohammed Al-Hatou (22225603)

"…Magnetic resonance imaging of the head and cervical spine showed global cerebellar atrophy with widened folia and decreased diameter of the upper cervical spine. Blood workup revealed hemolytic anemia with genetic testing confirmed a homozygous variant, c.514 T>A in exon 4 of the GCLC gene, resulting in Ser172Thr (TCC>ACC). …"

Insights on the effect of water content in carburizing gas mixtures on the metal dusting corrosion of iron حسب El Tayeb Bentria (9904024)

"…We demonstrate that the presence of water on a clean Fe surface promotes different catalytic reactions at the beginning of the simulations that boost the C, H, O diffusion into the sample. At later stage, the formation of oxide scale leads to an elevated concentration of H₂O/OH molecules on the surface due to the decrease in Fe affinity to dissociate water. …"

Electrospun polylactic acid/date palm polyphenol extract nanofibres for tissue engineering applications حسب Khadija M. Zadeh (14152338)

Improvement of heat sink performance using paraffin/graphite/hydrogel phase change composite coating حسب Sreedevi, Paramparambath

"…The W-G-H composite displayed nearly 12 folds more thermal conductivity compared to the pure paraffin wax. …"
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Enhancing the corrosion resistance of reinforcing steel under aggressive operational conditions using behentrimonium chloride حسب A. Bahgat Radwan (9631720)

"…<p dir="ltr">Aggressive operational conditions e.g. saline media and acidic gases, e.g., CO₂ can increase the corrosion rate of reinforcing steel. …"

Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Diseas... حسب Parkes J Kendrick (9714851)