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The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)
منشور في 2023"…These results reiterate the decisive role of 5-Aza-CdR in lung cancer treatment since it induces the epigenetic regulation of NY-ESO-1 antigen, inhibits cell proliferation, increases apoptosis, and decreases invasiveness.…"
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Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex
منشور في 2022"…<p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a>, published online 22 July 2022.…"
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Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO<sub>2</sub> Photocatalytic Nanocomposites Using the Zebrafish Embryo Model
منشور في 2019"…H<sub>2</sub>RGOTi showed a NOEC similar to RGOTi. However, no significant mortality was detected at all concentrations used in the acutoxicity assay (up to1000 mg/L), thus indicating a hypothetical LC<sub>50</sub> higher than 1000 mg/L. …"
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Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
منشور في 2019"…<p dir="ltr">Triple-negative breast cancer (TNBC) accounts for ~15–20% of breast cancer (BC) and has a higher rate of early relapse and mortality compared to other subtypes. The Chemokine (C-C motif) ligand 5 (CCL5) and its signaling pathway have been linked to TNBC. …"
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Non-diabetic ketoacidosis secondary to primary hyperthyroidism
منشور في 2022"…One infrequent complication of hyperthyroidism is non-diabetic ketoacidosis (NDKA). To the best of our knowledge, our case is the third report of NDKA related to thyrotoxicosis.…"
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The impact of climatic conditions on the carcinogenic and non-carcinogenic risk of BTEX compounds: A systematic review and meta-analysis
منشور في 2024"…For different climatic conditions, the overall mean and 95 % confidence interval (CI) of the effect size related to the carcinogenic and non-carcinogenic risk of BTEX were calculated using a random effect model. 26 articles passed the inclusion/exclusion criteria and were included in this review. …"
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Ferroelectric Properties and Electrocaloric Effect in Dy2O3 Substitution on Lead-Free (Na0.5 Bi0.5)0.94 Ba0.06TiO3 Ceramic
منشور في 2023"…Using the direct EC measurement, the ceramic corresponding to y = 0.02 exhibited a significant EC response, where ΔT = 1.2 K under 5 kV/mm. The incorporation of Dy was found to enhance the EC responsivity coefficient ζ = iT/ΔE), with a best value of ζ = 0.24 K.mm/kV for y = 0.02.…"
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Impaired histone deacetylases 5 and 6 expression mimics the effects of obesity and hypoxia on adipocyte function
منشور في 2016"…Similarly, hypoxia hampered total Hdac activity and reduced the expression of <i>Hdac5</i> and <i>Hdac6</i> in 3T3-L1 adipocytes. The decrease of both <i>Hdac5</i> and <i>Hdac6</i> by hypoxia was associated with altered expression of adipokines and of the inducible cAMP early repressor (Icer), a key repressor that is defective in human and mice obesity. …"
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A genetically encoded BRET-based SARS-CoV-2 Mpro protease activity sensor
منشور في 2022"…Further, in vitro assays with the BRET-based Mpro sensors revealed a molecular crowding-mediated increase in the rate of M<sup>pro</sup> activity and a decrease in the inhibitory potential of GC376. The sensors developed here will find direct utility in studies related to drug discovery targeting the SARS-CoV-2 M<sup>pro</sup> and functional genomics application to determine the effect of sequence variation in M<sup>pro</sup>.…"
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Effect of carbon nanotubes on the bonding mechanism of non-corrosive reinforcements to concrete
منشور في 2024"…This study aimed to assess the impact of waterborne pre-dispersed multiwall carbon nanotubes (MWCNTs) at a concentration of 0.2 wt % on the bond strength between concrete and non-corrosive reinforcements, including stainless steel (SS), glass fiber reinforced polymers (GFRP), and basalt fiber reinforced polymers (BFRP) bars. …"
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Effect of carbon nanotubes on the bonding mechanism of non-corrosive reinforcements to concrete
منشور في 2024"…<p>This study aimed to assess the impact of waterborne pre-dispersed multiwall carbon nanotubes (MWCNTs) at a concentration of 0.2 wt % on the bond strength between concrete and non-corrosive reinforcements, including stainless steel (SS), glass fiber reinforced polymers (GFRP), and basalt fiber reinforced polymers (BFRP) bars. …"
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Drying Studies of Purple Non-Sulphur Bacterial Biomass and Application as a Single-Cell Protein Feed for <i>Litopenaeus vannamei</i>
منشور في 2024"…</p><p dir="ltr">The results indicated a comparable growth of shrimps with the control for 15 and 30% PNSB blends having a growth rate between 0.50±0.08% to 0.53±0.07% by the end of the trial while the control had 0.49±0.04%. …"
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Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas
منشور في 2019"…CPHN cells represent a non-replicative pool of endocrine precursor cells, a proportion of which are likely fated to become beta-cells.…"
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Determinants of Non-Performing Loans in the State of Qatar With Special References to Small and Medium Enterprises
منشور في 2024"…<p dir="ltr">This research examines borrower-specific and bank-specific factors affecting Qatar's non-performing loans (NPLs). This is done by investigating the factors influencing SMEs' failure to meet their financial obligations with banks in Qatar. …"
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High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis
منشور في 2023"…HFNO was associated with a significant decrease in mortality and intubation rates (0.28 (95% CI; 0.19, 0.39) and 0.28 (95% CI; 0.18, 0.41), respectively). …"
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