يعرض 141 - 160 نتائج من 35,125 نتيجة بحث عن '(( 50 ppm decrease ) OR ((((( 50 nn decrease ) OR ( 50 c decrease ))) OR ( 5 we decrease ))))', وقت الاستعلام: 1.17s تنقيح النتائج
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    Expanding Three-Coordinate Gold(I) Anticancer Agent Chemical Space حسب Charles E. Greif (21728091)

    منشور في 2025
    "…The complexes demonstrated submicromolar cytotoxic activity against human breast cancer cells MDA-MB-231 or MDA-MB-468 with IC<sub>50</sub>’s in the range of 0.4–5.0 μM. Complex <b>2e</b> shows high potency in vitro and decreases 3D-breast cancer mammosphere viability. …"
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    Presentation_1_Eosinophils Decrease Pulmonary Metastatic Mammary Tumor Growth.pptx حسب Rachel A. Cederberg (12827564)

    منشور في 2022
    "…We found that IL5Tg mice exhibit reduced pulmonary metastatic colonization and decreased metastatic tumor burden compared to wild-type (WT) mice or eosinophil-deficient mice. …"
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    Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... حسب Shuai Wang (109515)

    منشور في 2021
    "…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …"
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    Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... حسب Shuai Wang (109515)

    منشور في 2021
    "…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …"
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    Isolation of Grain versus Intergranular Transport in Li<sub>1+<i>x</i></sub>Ti<sub><i>x</i></sub>Ta<sub>1–<i>x</i></sub>SiO<sub>5</sub> Suggests Concerted Ion Migration in a High-V... حسب Yu-Ying Lin (623528)

    منشور في 2023
    "…The grain and intergranular conductivities were separated using electrochemical impedance spectroscopy with distribution of relaxation times analysis (EIS/DRT). We showed the first clear observation of a monotonic decrease in activation energy <i>E</i><sub>A</sub> from 0.50 to 0.29 eV and a 6× increase in Li<sup>+</sup> conductivity in the grains to 2.49 × 10<sup>–5</sup> S/cm for <i>x</i> = 0.15 (30 °C) as more Li<sub>i</sub><sup>•</sup> were inserted, providing insight into how Li<sub>i</sub><sup>•</sup> potentially triggered concerted transport. …"
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    Isolation of Grain versus Intergranular Transport in Li<sub>1+<i>x</i></sub>Ti<sub><i>x</i></sub>Ta<sub>1–<i>x</i></sub>SiO<sub>5</sub> Suggests Concerted Ion Migration in a High-V... حسب Yu-Ying Lin (623528)

    منشور في 2023
    "…The grain and intergranular conductivities were separated using electrochemical impedance spectroscopy with distribution of relaxation times analysis (EIS/DRT). We showed the first clear observation of a monotonic decrease in activation energy <i>E</i><sub>A</sub> from 0.50 to 0.29 eV and a 6× increase in Li<sup>+</sup> conductivity in the grains to 2.49 × 10<sup>–5</sup> S/cm for <i>x</i> = 0.15 (30 °C) as more Li<sub>i</sub><sup>•</sup> were inserted, providing insight into how Li<sub>i</sub><sup>•</sup> potentially triggered concerted transport. …"
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    Decreased phosphorylation of EIF2α underlies the impairment of arsenite-induced SG formation in LSM12-depleted cells. حسب Jongbo Lee (9914603)

    منشور في 2020
    "…Control<sup>shRNA</sup> and <i>LSM12</i><sup>shRNA</sup> cells were incubated with 0.4-M sorbitol for the indicated time before co-staining with anti-ATXN2 antibody (red), anti-G3BP1 antibody (green), and Hoechst 33258 (blue). (B, C) LSM12 depletion decreases the arsenite-induced phosphorylation of EIF2α. …"
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    The GluN2B-C456Y mutation decreases recombinant NMDAR currents and alters receptor properties. حسب Wangyong Shin (6793040)

    منشور في 2020
    "…<p>(A) The GluN2B-C456Y mutation strongly decreases diheteromeric GluN1/GluN2B NMDAR currents in <i>Xenopus</i> oocytes. …"
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