Behavior of split^<50cM <i>ClvR</i> V1 with linkage. by Georg Oberhofer (3401438)

Behavior of split^<50cM <i>ClvR</i> V2 with linkage. by Georg Oberhofer (3401438)

“…<p>Incorporating linkage into split <i>ClvR</i> (split^<50cM <i>ClvR</i> V2) results in a graded increase in drive strength, and duration of <i>Rescue</i>/Cargo/gRNAs at high frequency, as the degree of linkage increases (map distance decreases). …”

Downregulation of DOM decreases the abundance of PER and TIM. by Zhenxing Liu (399809)

“…Downregulation of DOM decreased PER levels at CT1-5 and CT17-21. (Scale bar: 50 um.) …”

mGluR5 receptor decreased glycinergic currents. by Zi-Yang Zhang (4988555)

“…The original traces were taken at the time points indicated by the numbers 1–3. (<b>C</b>) The inhibitory effect of DHPG on GlyR-IPSCs was blocked by MPEP (92.4 ± 4.4% of baseline at 15–20 min post-DHPG, <i>t</i>[5] = 1.573, <i>p</i> = 0.177) but not by CPCCOEt (53.5 ± 3.7% of baseline at 15–20 min post-DHPG, <i>t</i>[5] = 14.343, <i>p</i> < 0.001). …”

Bacterial co-abundance networks decreases in complexity with lower host genetic variation. by Michael Ørsted (5926028)

Population dynamics modeling of split^50cM <i>ClvR</i> V1 introduced at a 50% release, with fitness cost per allele varying from 0–15%. by Georg Oberhofer (3401438)

Germ cell size decreases before corpse formation. by Tea Kohlbrenner (19476160)

Ammonia (NH₃) measurement (ppm) on the last day of a cage-change cycle in the front, middle and rear of the cage, for each site and sex. by B. Ulfhake (6293984)

Subjects:

Population dynamics of <i>Killer-Rescue</i>/Cargo, <i>ClvR</i> and split^50cM <i>ClvR</i> V2. by Georg Oberhofer (3401438)

Bacterial growth load (CFUs) and average of NH₃ ppm across the cage-change cycle in cages changed bi-weekly (filled circles) vs. weekly (open circles). by B. Ulfhake (6293984)

Subjects:

Boxplots of average NH₃ ppm in cages with four female or four male mice (see key for male and female) across five cage changing cycles at KI, LUMC and UGA. by B. Ulfhake (6293984)

Subjects:

Equilibrium points and their corresponding eigenvalues of Eq (5). by Xinghua Fan (7344632)

Additional behavioral patterns in the 5€, 100€, and 1000€ treatments. by Pablo Brañas-Garza (336425)

Drive dynamics for split^<50cM <i>ClvR</i>s with different genetic linkage and migration rates. by Georg Oberhofer (3401438)

Intravenous treatment of naïve wild-type mice with PrP LSPCs decreased PrP^C mRNA and cell surface PrP^C protein at various time points. by Heather Bender (363996)

SARS-CoV-2 inhibits SG formation and decreases expression of G3BP1. by Stacia M. Dolliver (13822801)

Point elasticity of demand decreasing price by Rod Shaw (1258020)

Population dynamics modeling of split^50cM <i>ClvR</i> V1 drive introduced at different release percentages, and an example illustrating the role that LOF alleles play in... by Georg Oberhofer (3401438)

“…(<b>G-I)</b> One way to appreciate the power of the latent drive force provided by LOF alleles that segregate independently of the <i>Rescue</i>/Cargo is to consider a split^50cM <i>ClvR</i> population in which a <i>Rescue</i>/Cargo/gRNAs with no fitness cost has spread to allele fixation, the Cas9 driver chromosome has been completely eliminated (as would happen during drive if the presence of Cas9 resulted in a fitness cost to carriers, discussed below), and all endogenous copies of the essential gene have been rendered LOF (generation 0 in <b>G-I</b>). …”

Juvenile demyelination leads to a decrease in axonal complexity of PFC PV interneurons. by Sara Hijazi (21656615)

“…The number of branch points in PV interneuron axons from cuprizone-treated mice was significantly decreased compared to control mice (<i>t test; n = 10/9 cells per group, *p < 0.05</i>). …”

HFD induces LDs and decreases ER and mitochondria in nephrocytes. by Aleksandra Lubojemska (10746241)

“…(<b>E</b>) Low and high magnification views of pericardial nephrocytes (dotted outlines) from STD and HFD larvae, showing that HFD decreases mitochondria (marked with anti-ATP5A) and ER (marked with anti-KDEL) but increases LDs (marked with LipidTOX). …”