Showing 21 - 40 results of 6,758 for search '(( 50 ppm decrease ) OR ((( 50 n decrease ) OR ((( 5 ng decrease ) OR ( 5 nm decrease ))))))', query time: 1.00s Refine Results
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    Discovery of Novel Pyrimidine-Based Capsid Assembly Modulators as Potent Anti-HBV Agents by WooChan Kim (10690503)

    Published 2021
    “…One of the synthesized derivatives, compound <b>23h</b> (R<sup>1</sup> = MeSO<sub>2</sub>, R<sup>2</sup> = 1-piperidin-4-amine, R<sup>3</sup> = 3-Cl-4-F-aniline) displayed potent inhibitory effects in the in vitro assays (52% inhibition in the protein-based assay at 100 nM and an IC<sub>50</sub> value of 181 nM in the serum HBV DNA quantification assay). …”
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