Image_3_Decreased Opioid Consumption in Bone Marrow Harvest Patients Using Quadratus Lumborum Blocks in a Standardized Protocol.PDF by Nicole C. McCoy (12459036)

“…The implementation group showed significantly reduced median intraoperative (20.0 mg vs. 0.0 mg; p < 0.001) and total opioid consumption (20.5 mg vs. 0.0 mg; p < 0.001). The number of patients who received any opioids decreased from 84.2% (16/19) before implementation to 23.1% (3/13) after implementation.…”

DataSheet_1_Failure to decrease HbA1c levels following TB treatment is associated with elevated Th1/Th17 CD4+ responses.pdf by Robert Krause (504842)

“…Participants were stratified based on stable/increased HbA1c (n = 16) versus decreased HbA1c (n = 46) levels from treatment initiation to 12 month follow-up.…”

The LCS stream is absent in E16.5 <i>Emx1</i>-cKO mice. by Sathish Venkataramanappa (10331993)

Fig 5 - by Qingxi Shen (3547970)

A genetic variant in human FIRE is associated with a decreased interferon response in myeloid cells. by Anaïs Assouvie (9600529)

19606 decreases the luminal pH of the ACV during infection. by Jesus S. Distel (11250759)

Combination of cAMP-enhancing and cAMP-inhibiting neuromodulation can increase or decrease the AP threshold throughout the apical dendrite in the Hay-model L5PC. by Tuomo Mäki-Marttunen (388882)

LC-IMS-CID-MS CKO vs K5Cre results. by Kevin J. Mills (9270966)

“…<div><p>CCAAT/enhancer binding protein- (C/EBP) is a basic leucine zipper transcription factor that is abundantly expressed in epidermal keratinocytes of skin. …”

Increasing TPP side chain length decreases melanoma cell viability and clonogenic survival. by Kyle C. Kloepping (9928265)

“…A375 melanoma cells were treated with 0.25 μM, 0.5 μM, or 1.0 μM 5-, 8-, 10-, 12-,14-, or 16-TPP for (C) 24 h and (D) 48 h and analyzed for clonogenic survival (* represents when 12-, 14-, and 16-TPP were significant relative to 5-TPP and 8-TPP; Ψ represents when 10-TPP was significant relative to 5-TPP and 8-TPP; p < 0.05; n = 3 from 2 separate experiments; N = 6). …”

Image_5_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”

5-year risk of cardiovascular diseases under exposure deciles of A) HbA1C-CV and B) FPG-CV. by Khadije Maajani (10125692)

Subjects:

I348T increases H77 entry dependency on SR-BI, while T385P decreases H77 entry dependency on SR-BI. by Christina Holmboe Olesen (11154333)

C/EBPα binds five sites within the <i>Cebpa</i> +8 kb enhancer. by Lei Peng (260321)

Subjects:

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Vanadium(V^IV)–Porphyrin-Based Metal–Organic Frameworks for Synergistic Bimetallic Activation of Inert C(sp³)–H Bonds by Yefei Wang (430888)

“…Herein, by decorating vanadium­(V^IV)–porphyrin into metal–organic frameworks (MOFs) to stabilize the active tertbutyl peroxide radical, we reported a new approach to accomplish inert C­(sp³)–H bond activation by a synergistic bimetallic strategy via a hydrogen atom transfer process under mild conditions. …”

pDNA-PK levels are decreased in absence of cGAS. by Elona Gusho (4688170)

Absence of FumC leads to decreased susceptibility to bactericidal antibiotics. by Stephanie D. Himpsl (8501868)

Juvenile demyelination leads to a decrease in axonal complexity of PFC PV interneurons. by Sara Hijazi (21656615)

“…</b> Quantification of the overall myelin intensity in PFC of both groups shows a clear loss of myelin in the juvenile demyelination group (<i>t test; n = 6/5 mice per group, ***p < 0.001</i>). …”

JBPOS0101 decreased Amyloid Beta (Aβ) aggregates in the cortex and hippocampal regions in 5xFAD mouse brains. by Jihoon Jeong (4852690)