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c decrease » c decreased (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
ms decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
nn decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
c decrease » c decreased (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
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2‑Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2)
Published 2023“…To develop more potent compounds, we initiated a structure–activity relationship study that identified 2-aminobenzoxazole as a viable scaffold. …”
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Integration of Segmented Ion Fractionation and Differential Ion Mobility on a Q‑Exactive Hybrid Quadrupole Orbitrap Mass Spectrometer
Published 2021“…FAIMS was also combined with segmented ion fractionation where 100 <i>m</i>/<i>z</i> windows were obtained in turn to further increase the depth of proteome analysis by reducing the proportion of chimeric MS/MS spectra from 50 to 27%. We also demonstrate the application of FAIMS to improve quantitative measurements when using isobaric peptide labeling. …”
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Integration of Segmented Ion Fractionation and Differential Ion Mobility on a Q‑Exactive Hybrid Quadrupole Orbitrap Mass Spectrometer
Published 2021“…FAIMS was also combined with segmented ion fractionation where 100 <i>m</i>/<i>z</i> windows were obtained in turn to further increase the depth of proteome analysis by reducing the proportion of chimeric MS/MS spectra from 50 to 27%. We also demonstrate the application of FAIMS to improve quantitative measurements when using isobaric peptide labeling. …”
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Integration of Segmented Ion Fractionation and Differential Ion Mobility on a Q‑Exactive Hybrid Quadrupole Orbitrap Mass Spectrometer
Published 2021“…FAIMS was also combined with segmented ion fractionation where 100 <i>m</i>/<i>z</i> windows were obtained in turn to further increase the depth of proteome analysis by reducing the proportion of chimeric MS/MS spectra from 50 to 27%. We also demonstrate the application of FAIMS to improve quantitative measurements when using isobaric peptide labeling. …”
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Integration of Segmented Ion Fractionation and Differential Ion Mobility on a Q‑Exactive Hybrid Quadrupole Orbitrap Mass Spectrometer
Published 2021“…FAIMS was also combined with segmented ion fractionation where 100 <i>m</i>/<i>z</i> windows were obtained in turn to further increase the depth of proteome analysis by reducing the proportion of chimeric MS/MS spectra from 50 to 27%. We also demonstrate the application of FAIMS to improve quantitative measurements when using isobaric peptide labeling. …”
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Decreased phosphorylation of EIF2α underlies the impairment of arsenite-induced SG formation in LSM12-depleted cells.
Published 2020“…(B, C) LSM12 depletion decreases the arsenite-induced phosphorylation of EIF2α. …”
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Disrupting Glycolysis-promoting Genes Extends <i>C</i>. <i>elegans</i> Healthspan, Whereas High Glucose and Gluconeogenic Gene Disruptions Shorten Healthspan.
Published 2020“…We note that, in our hands, disruption of C50F4.2 (<i>pfk-1</i>.…”
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