Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

“…Here, by addressing a high-energy water, we improved the IC₅₀ value of our co-crystallized glycogen synthase kinase-3β (GSK-3β) inhibitor by nearly two orders of magnitude. …”

Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

“…Here, by addressing a high-energy water, we improved the IC₅₀ value of our co-crystallized glycogen synthase kinase-3β (GSK-3β) inhibitor by nearly two orders of magnitude. …”

The introduction of mutualisms into assembled communities increases their connectance and complexity while decreasing their richness. by Gui Araujo (22170819)

“…(C) Mutualism also promotes an increase in network connectance when introduced into assembled communities, while stopping mutualistic interactions from entering an assembled system slowly decreases it. (D) As a result, the introduction of mutualistic interactions promotes a growth in complexity in communities where it was once established as low, while stopping the introduction of further mutualistic interactions causes a slight decrease in complexity. …”

Crosslinking decreases the alignment of fibers associated with individual cells migrating out of spheroids. by Michael Pamonag (12295175)

Affinity analysis results (with a confidence level above 50%). by Marta R. Jabłońska (8491404)

Loss of Slfn3 induces a gender-dependent repair vulnerability after 50% bowel resection by Emilie DeKrey (9389738)

Genes whose expression was decreased by 100 nM ouabain by more than 1.3-fold. by Larisa V. Smolyaninova (3600053)

Results isoprenaline (30nM) experiment. by L. Cao (3526226)

Concentrations of particles that caused significant decreases in the viability of SNU-1 cells compared to untreated cells during 1, 2, 4, 6 or 24 h treatment periods. by Amrita Banerjee (382658)

Trial profile. by Chanel Avenant (409756)

“…<div><p>HIV acquisition risk with norethisterone (NET) enanthate (NET-EN) is reportedly less than for depo-medroxyprogesterone acetate intramuscular (DMPA-IM). We investigated the effects of these progestin-only injectable contraceptives on serum testosterone and sex hormone binding globulin (SHBG) levels, since these may play a role in sexual behavior and HIV acquisition. …”

UPLC-DAD profile (270 nm) of phytocannabinoids in the extracts separated in C18 column. by Bruno Musetti (9527085)

Image 1_Exploration of the diagnostic and prognostic roles of decreased autoantibodies in lung cancer.tif by Ying Ye (72583)

Expression of ApoB-50 decreased lipid accumulation and inhibited HCV production. by Bei Wang (116772)

All-cause gastroenteritis hospitalisations of children decreased after the introduction of rotavirus vaccine in Stockholm by Selma Olsson-Åkefeldt (11500789)

Image_1_Electroencephalographic Evidence for Individual Neural Inertia in Mice That Decreases With Time.JPEG by Andrzej Z. Wasilczuk (11945885)

“…EEG was measured after induction of and emergence from isoflurane administered near the EC₅₀ dose for loss of righting in genetically inbred mice on a timescale that minimizes pharmacokinetic confounds. …”

Image_1_Decreased Systemic and Airway Sirtuin 1 Expression in Adults With Bronchiectasis.TIF by Xiao-rong Han (8470563)

Image_3_Decreased Systemic and Airway Sirtuin 1 Expression in Adults With Bronchiectasis.TIF by Xiao-rong Han (8470563)

Image_2_Decreased Systemic and Airway Sirtuin 1 Expression in Adults With Bronchiectasis.JPEG by Xiao-rong Han (8470563)

Table_2_Decreased Systemic and Airway Sirtuin 1 Expression in Adults With Bronchiectasis.DOCX by Xiao-rong Han (8470563)

Image_4_Decreased Systemic and Airway Sirtuin 1 Expression in Adults With Bronchiectasis.TIF by Xiao-rong Han (8470563)