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Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy...
منشور في 2024"…FindingsIn 2021, diarrhoeal diseases caused an estimated 1·17 million (95% uncertainty interval 0·793–1·62) deaths globally, representing a 60·3% (50·6–69·0) decrease since 1990 (2·93 million [2·31–3·73] deaths). …"
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182
A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase
منشور في 2019"…Considering true positives, true negatives, false positives, and false negatives, three mutations (Y114E, R128G, and C145A) showed "loss of DNA repair activity," and were analyzed further using molecular dynamics simulations (MDS) using GROMACS for 50ns. MDS run showed that the C145A mutant demonstrated higher structural deviation, decreased compactness, and the binding patterns. …"
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Prediction of biogas production from chemically treated co-digested agricultural waste using artificial neural network
منشور في 2020"…The results demonstrated that co-digestion of ASWs with CM with a ratio of 70% to 30% produced the highest CMP of 334 ± 4 NL/kgVS in comparison with 230 ± 10 NL/kgVS for mono-digested substrate. The CMP was the highest for the substrate with moisture content (%MC) in the range of 34% to 48%, and it decreased for %MC > 50%. …"
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Silicon Enhances Morpho–Physio–Biochemical Responses in Arsenic Stressed Spinach (Spinacia oleracea L.) by Minimizing Its Uptake
منشور في 2022"…Although, the activities of enzymatic antioxidants such as superoxidase dismutase, peroxidase, catalase, ascorbate peroxidase in the roots and shoots of the plants and non-enzymatic such as phenolic, flavonoid, ascorbic acid, and anthocyanin contents were initially increased with the exposure of 50 µM As, but decreased by the increasing the As concentration 100 µM in the soil. …"
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190
Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria
منشور في 2024"…We observed that the disease-associated K72I genetic variant had no apparent effects on the spectroscopic and catalytic properties of the full-length enzyme. …"
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Cyclic voltammetry and XPS studies of poly (aniline-co-3-aminophenol)
منشور في 2022"…In the electrochemical study, the copolymers differ from PA in the single-electron oxidation and reduction, reversibly at various scan rates ranging from 20 to 50 mV. The current density decreases from PA-co-3-AP20 to PA-co-3-AP80 by increasing the loading weight percentage of 3-aminophenol in the polymeric backbone. …"
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Salvia fruticosa Induces Vasorelaxation in Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway
منشور في 2017"…Prior exposure to PI3K inhibitors, wortmannin (0.1 µM) or LY294002 (10 µM), decreased cGMP accumulation and attenuated the SF-induced vasorelaxation by approximately 50% (Rmax). …"
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Burden and trend of diet-related non-communicable diseases in Australia and comparison with 34 OECD countries, 1990-2015: findings from the Global Burden of Disease Study 2015.
منشور في 2018"…Young (25-49 years) and middle-age (50-69 years) male adults had a higher PAF of diet-related NCD deaths and DALYs than their female counterparts. …"
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