Tacrolimus Decreases Albuminuria in Patients with IgA Nephropathy and Normal Blood Pressure: A Double-Blind Randomized Controlled Trial of Efficacy of Tacrolimus on IgA Nephropathy by Yong-Chul Kim (1637572)

“…The pre-defined secondary outcomes were better in the Tac group compared to the control group. The frequency of decrease in pcUACR and percentage change of UPCR (pcUPCR) ≥50% at 16 weeks were 65.0% (13/20) and 55.0% (11/20)in the Tac group, and 25.0% (5/20) and 15.0% (3/20), in the control group, respectively (p = 0.025 for pcUACR and p = 0.019 for pcUPCR). …”

<i>Slc13a5</i>^<i>-/-</i> mice had decreased enamel volume as measured with μCT. by Armando R. Irizarry (422739)

Taurolidine lock solution for catheter-related bloodstream infections in pediatric patients: A meta-analysis by Yan Sun (22436)

“…The number of catheters removed due to infection or suspected infection was not significantly different between the two groups (RR: 0.68; 95% CI:0.22, 2.10; I² = 56%; P = 0.50) (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0231110#pone.0231110.g005" target="_blank">Fig 5</a>). …”

Generation and characterization of an antagonistic monoclonal antibody against an extracellular domain of mouse DP2 (CRTH2/GPR44) receptors for prostaglandin D₂ by Nanae Nagata (3916574)

“…This antibody inhibited the binding of 0.5 nM [³H]PGD₂ to mouse DP2 (IC₅₀ = 46.3 ± 18.6 nM), showed antagonistic activity toward 15(R)-15-methyl PGD₂-induced inhibition of 300 nM forskolin-activated cAMP production (IC₅₀ = 16.9 ± 2.6 nM), and gave positive results for immunohistochemical staining of DP2-expressing CD4+ Th2 lymphocytes that had accumulated in the kidney of unilateral ureteral obstruction model mice. …”

Reduced follicles, decreased ovulation and decreased fertilization of female Meox-2-cre/Separase S1121A mutant mice. by Juan Xu (225010)

3‑Hydroxyquinolin-2-Ones Act as Dual Inhibitors of Ferroptosis and Monoamine Oxidase B: Reducing Alzheimer’s Disease-Related Amyloid Precursor Protein and Hyperphosphorylated Tau I... by Yangjing Lv (21580685)

“…Additionally, overexpression of monoamine oxidase B (MAO-B) induces oxidative stress and decreases cognitive function. In this study, we presented the novel dual inhibitors of ferroptosis and MAO-B for AD management, aiming to address both the symptomatic and neurodegenerative aspects of this disease. …”

Table S1 - Human <i>NR5A1</i>/SF-1 Mutations Show Decreased Activity on BDNF (Brain-Derived Neurotrophic Factor), an Important Regulator of Energy Balance: Testing Impact of Novel SF-1 Mutations Beyond Steroidogenesis by Jana Malikova (615672)

Subjects:

Decrease of viral load and ALT at different time points under treatment according to NS5A-inhibitors and interferon administration. by Valeria Cento (103603)

Localization of key HH signaling proteins is impaired in <i>Ttbk2</i>^{<i>sca11/gt</i>} cilia. by Emily Bowie (543704)

Treatment with low doses of GI254023X causes a mild decrease in ADAM10 surface expression that correlates with a marked impairment of HCV infectivity. by Belén Carriquí-Madroñal (17396512)

GREAT GO analysis of WDR5 and MYCN overlapped ChIP-seq peaks with >2.5-fold decrease of WDR5 signal intensity after the silencing of <i>WDR5</i>. by Zhihui Liu (95891)

BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell by Jude T. Deeney (335344)

“…JQ1 (50–400 nM) increases insulin secretion from INS-1 cells in a concentration dependent manner. …”

(A) FACS analysis of cell surface markers on untreated or 5 nM Bortezomib treated mature dendritic cells. by Daniela Grabher (383863)

“…<p>Maturation marker expression (CD80, CD83 and CD86, MHC class I and MHC class II) on mature dendritic cells and mature dendritic cells treated with 5 nM Bortezomib were measured. Maturation markers show no difference when treated with 5 nM Bortezomib. …”

A Peptide Mimetic of 5-Acetylneuraminic Acid-Galactose Binds with High Avidity to Siglecs and NKG2D by Laura L. Eggink (760403)

“…Using plant lectins as analogs of lectin-type cell-surface receptors, a tetravalent form of a peptide with the sequence NPSHPLSG, designated svH1C, bound with high avidity to lectins specific for glycans with terminal 5-acetylneuraminic acid (Neu5Ac)-galactose (Gal)/N-acetylgalactosamine (GalNAc) sequences. …”

The decrease of C/EBPα protein during apoptosis involves induction of protein degradation and inhibition of transcription. by Meng Zhao (54299)

“…<p>(A) After pretreatment with 25 nM of NSC606985 or 0.5 µM of etoposide for 12 hours, NB4 cells were incubated with 10 µg/ml CHX for indicated hours. …”

Non-hydrolysable ATP analogues prevent decrease of I_Ca,L by metabolic inhibition. by Giedrius Kanaporis (4405525)

Data_Sheet_1_Effectiveness of non-pharmaceutical interventions in nine fields of activity to decrease SARS-CoV-2 transmission (Spain, September 2020–May 2021).PDF by Inés Barbeito (5864351)

“…In a reduced model with seven fields, culture and leisure no longer had a significant effect while ceremonies decreased transmission by 5% (0.95; 0, 0.96). …”

Surveillance of HIV Transmitted Drug Resistance in Latin America and the Caribbean: A Systematic Review and Meta-Analysis by Santiago Avila-Rios (3160959)

Subjects:

S5 Data - by Christoph Anders (4068499)

“…The study was conducted with 25%, 50%, and 75% of the upper body weight. Additionally, we varied the starting point (forward tilt and backward tilt) and the direction of rotation. …”

Mechlorethamine gel causes epithelium thinning, epithelium-stroma separation, and decreased total stroma cell count. by Ana M. Sandoval-Castellanos (11611315)

“…<p>A) Epithelium thickness decreased, and B) the percentage of epithelium-stroma separation increased after NM exposure. …”