MEK inhibition decreases mTOR activity in T cells. by Marie Le Borgne (337225)

Pyrimidine nucleotides are decreased in hypoxia, while precursors accumulate. by Emily B. Cohen (9106088)

L-2286 treatment decreased the deposition of interstitial collagen. by Laszlo Deres (596720)

Epidermal GATA3 expression is decreased in psoriatic lesions. by Emőke Rácz (220871)

GSK343 decreased neuroblastoma viability, proliferation, and motility. by Laura V. Bownes (10276762)

“…<p>(A) SK-N-AS, SK-N-BE(2), SH-EP and WAC(2) cells (1.5 × 10³ cells) were treated with increasing concentrations of GSK343 (0, 5, 15, 25 μM) for 24 hours and viability was measured using alamarBlue^® assay. …”

Fig 5 - by Lingru Ruan (18995544)

<i>ism1</i> knockdown decreases erythrocytes. by Arturo Berrun (5216003)

Bortezomib decreases osteoclasts and improves fracture repair in mice. by Hengwei Zhang (2397610)

MMR mutants show decreased mating-type silencing. by Qian Liu (135614)

“…<i>sir1Δ</i> mutant was used as a positive control. <b>(D)</b> Cells of indicated strains were 10-fold serially diluted and then spotted onto SC (left), SD-Ura (middle) and SC+FOA(right) agar plates, the <i>sir1Δ</i> mutant served as a positive control. …”

Antineoplastic Effects of siRNA against TMPRSS2-ERG Junction Oncogene in Prostate Cancer by Giorgia Urbinati (554921)

“…Two of the five siRNAs tested were found to efficiently inhibit mRNA of both <i>TMPRSS2-ERG</i> variants and to decrease ERG protein expression. …”

Hemodiafiltration Decreases Serum Levels of Inflammatory Mediators in Severe Leptospirosis: A Prospective Study by Sérgio Aparecido Cleto (3143949)

“…<div><p>Background</p><p>Leptospirosis is a health problem worldwide. Its most severe form is a classic model of sepsis, provoking acute respiratory distress syndrome (ARDS) and acute kidney injury (AKI), with associated mortality that remains unacceptably high. …”

Fold change with steady state myocardial mRNA levels for components of the inflammasome. by Stephanie L. Samani (17896610)

Subjects:

Deficiency in ArgEF or CpcA but not ArgB decreases the cellular ornithine content. by Nicola Beckmann (194193)

I348T increases H77 entry dependency on SR-BI, while T385P decreases H77 entry dependency on SR-BI. by Christina Holmboe Olesen (11154333)

A Functional 12T-Insertion Polymorphism in the <i>ATP1A1</i> Promoter Confers Decreased Susceptibility to Hypertension in a Male Sardinian Population by Victoria L. Herrera (383897)

“…To test the effects of decreased α1Na,K-ATPase expression on blood pressure, we measured blood pressure by radiotelemetry in three month-old, highly inbred heterozygous knockout <i>ATP1A1+/−</i> male mice with resultant 58% reduction in ATP1A1 protein levels. …”

Cell adhesion was decreased by simvastatin and benznidazole during <i>Trypanosoma cruzi</i> infection. by Carolina Campos-Estrada (403914)

TGFβ1 expression was increased, and RASAL1 expression was decreased in NTM cells in response to a hypoxic environment. by Fiona McDonnell (2636635)

“…</b> After 24 hours, RASAL1 was decreased; fold change 0.51+/-0.13 (P<0.05). <b>C.</b> Western blotting shows an apparent increase in TGFβ1 after 6 hours. …”

Heatmap of metabolites with at least 1.5-fold change (increase or decrease) from 0h following treatment with or without PMA for 5 and 15 min. by Susama Chokesuwattanaskul (5813888)

Deletion of <i>Kdm5b</i> in DCs leads to increased cytokine production and decreased Th2 pathology <i>in vivo</i>. by Catherine Ptaschinski (756139)

Folding and stability of GDAP1 as affected by CMT mutations. by Aleksi Sutinen (10039145)

Subjects: