Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Repeated LSPC treatment prolongs survival of and decreases PrP^Res accumulation in a subset of prion-infected mice. by Heather Bender (363996)

Data_Sheet_1_Microclimatic Warming Leads to a Decrease in Species and Growth Form Diversity: Insights From a Tropical Alpine Grassland.PDF by Sisimac A. Duchicela (11503918)

“…We installed five monitoring blocks in 2012 at ca. 4,200 m asl with 20 OTCs and 50 control plots randomly distributed within each block. …”

Obstacle avoidance trajectory generation process based on DMP (for specific trajectory point data, please refer to the attachment ‘S5 Table.xlsx’. For detailed descriptions of the... by Long Di (9977453)

Bacterial intracellular survival increases <i>in vivo</i> persistence in a mouse model of urinary tract infection and decreases antibiotic efficacy. by Cristina Penaranda (433703)

<b>Reduced legacy precipitation decreases microbial community growth efficiency and alters soil organic carbon in a California grassland</b> by Linnea Honeker (13113813)

Five-hours-old clots were subjected to scanning electron microscopy. by Jan Víteček (11434774)

Supplementary data 1: database with extracted data from Combined effects of warming and drought on plant biomass depend on plant woodiness and community type: a meta-analysis by Rutger A. Wilschut (13853921)

Average nearest neighbour analysis before and after filtering of data points. by Dennis Ochola (11626912)

Claudin V is decreased following infection with Mtb. by Amanda S. Latham (12093638)

“…<p>Immunofluorescent staining of guinea pig brain tissue for DAPI (blue) and claudin V (cyan) in vessels was performed. Representative images of the frontal cortex (A–D), cerebral nuclei (F–I), brain stem (K–N), thalamus (P–S), and hippocampus (U–X) 15 days post-infection are shown. …”

Cost-effectiveness and budget impact of immediate antiretroviral therapy initiation for treatment of HIV infection in Côte d’Ivoire: A model-based analysis by Eric N. Ouattara (6890174)

“…<i>Immediate ART</i> increased the 5-year HIV care budget from $801.9M to $812.6M compared to <i>ART<350/μL</i>.…”

Brain uptake rate of [¹⁴C]docosahexaenoic acid (DHA) in the whole brain and each brain region. by Takuro Iwao (14636741)

Subjects:

Brain uptake rate of [¹⁴C]sucrose in the whole brain and individual brain regions. by Takuro Iwao (14636741)

Subjects:

Fig 5 - by Ke Lu (124270)

Subjects:

Fig 5 - by Melissa K. Peckins (12042132)

Colored points represent the dates where events from Fig 7, have a <i>p</i>-value below the <i>α</i> = 0.05 significance level, i.e. dates where the statistical behavior of the dur... by Héctor Raúl Olivares-Sánchez (13014866)

Effect sizes (if > 0.5) for the comparison of increasing load vs. decreasing load for the multifidus muscle. by Christoph Anders (4068499)

Effect sizes (if > 0.5) for the comparison of increasing load vs. decreasing load for the longissimus muscle. by Christoph Anders (4068499)

PGRN deletion decreased the susceptibility to invasive <i>C</i>.<i>albicans</i> infection in mice. by Jiayu Liu (3951515)

Ppk1 levels are not affected by decreasing dendrite arbor size but are reduced when dendrite length increases. by Josephine W. Mitchell (17364781)