Saliency maps were employed in order to elucidate which part of the B-scan images the machine learning focused on during training in Model 1. by Taku Toyama (102864)

Supplementary Material for: Activation of KCNQ2/3 Potassium Channels by Novel Pyrazolo[1,5-a]pyrimidin-7(4H)-One Derivatives by Jia C. (4126141)

“…Here, we report that four novel synthesized derivatives of pyrazolo[1,5-a]pyrimidin-7(4H)-one (PPO) named QO-26, QO-28, QO-40 and QO-41 potently augmented KCNQ2/3 channels expressed in Chinese hamster ovary cells and shifted the half-maximal activation voltage (V_1/2) in the hyperpolarizing direction. …”

DNA epitope vaccine reduces Aβ depositions in the brains of immune 3xTg-AD mice at age 18±0.5 mo. by Nina Movsesyan (86328)

“…Shown are representative images of ThS-stained hemibrains of vaccinated or control mice were (scale bar 300 µm), S-subiculum. C) As a result of DNA epitope vaccination, significant reduction (***P<0.001) of insoluble Aβ₄₂ level in brain homogenates was observed, although, decrease in level of insoluble Aβ₄₀ was not statistically significant. …”

OCT at 1 month after phacoemulsification. by Jurica Predović (18334274)

S1 Data - by Hao Deng (409186)

“…ERCC1 significantly decreased in processing of CWP. The cutoff value of ERCC1 was 5.265 pg/ml, with a sensitivity of 90.0% and specificity of 86.7%. …”

Individual (in grey) and overall (in black) median adjustment errors at the beginning (left column) and at the end (right column) of each five-minute run derived from the fitted tr... by Alexander A. Tarnutzer (299365)

“…While panels A and C show all traces with significantly increasing errors over time, panels B and D illustrate traces that had a significant decrease in error.…”

Conophylline inhibits high fat diet-induced non-alcoholic fatty liver disease in mice by Tomohiko Ohashi (4096861)

“…CnP (0.5 and 1 μg/g/body weight) was co-administered along with a high-fat diet to male BALB/c mice. …”

Change in the genotypes of <i>ATM</i>, <i>ERCC1</i>, and <i>XRCC1</i>. by Hao Deng (409186)

“…ERCC1 significantly decreased in processing of CWP. The cutoff value of ERCC1 was 5.265 pg/ml, with a sensitivity of 90.0% and specificity of 86.7%. …”

Optogenetic stimulation of cultured astrocytes increases the expression of <i>Lcn2</i> and proinflammatory cytokines. by Jae-Hong Kim (124622)

OPTN activates canonical Wnt signaling pathway in myoblasts. by Xiao Chen Shi (8611887)

LPS induces an immediate inflammatory response; PFC does not. by Heather F. Pidcoke (9023789)

Structural adaptations of octaheme nitrite reductases from haloalkaliphilic <i>Thioalkalivibrio</i> bacteria to alkaline pH and high salinity by Anna Popinako (4028573)

“…The following adaptation strategies were observed: (1) strategies specific for halophilic and alkaliphilic proteins (an increase in the number of aspartate and glutamate residues and a decrease in the number of lysine residues on the protein surface), (2) strategies specific for halophilic proteins (an increase in the arginine content and a decrease in the number of hydrophobic residues on the solvent-accessible protein surface), (3) strategies specific for alkaliphilic proteins (an increase in the area of intersubunit hydrophobic contacts). …”

First choice. by Caroline I. Jahn (14522732)

Descriptive statistics of the surveys for all data collection years combined. by Diego Montano (4377373)

The knockout strategy of <i>Nsun2</i> in C57BL/6JGpt mice and genotyping strategy. by Jiangpeng Feng (9287738)

Root mean square error (<i>RMSE</i>) of the predictions for the <i>second</i> round. by Corentin Vande Kerckhove (2852168)

“…In (B), the <i>RMSE</i> has been scaled by a factor of 5 to be comparable to the (A) plot. …”

Dexamethasone treatment modifies <i>PTGDR</i> expression levels. by Elena Marcos-Vadillo (4557103)

Dexamethasone treatment modifies <i>PTGDR</i> promoter activity. by Elena Marcos-Vadillo (4557103)

OPTN degrades GSK3β via activating LC3-mediated autophagy. by Xiao Chen Shi (8611887)

Mean and two standard deviations from LNA versus stochastic simulations for Lotka-Volterra model. by Christoph Zimmer (3095667)

“…<p>The upper row shows 100 stochastic simulations in gray color and the mean from a LNA in solid red color as well as mean plus and minus two standard deviations in dashed red color. …”