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point decrease » point increase (Expand Search)
we decrease » _ decrease (Expand Search), mean decrease (Expand Search), teer decrease (Expand Search)
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15461
Data Sheet 1_A dietary combination of red yeast rice, phytosterol ester and lycopene ameliorates hypercholesterolemia by regulating gut microbiota and activating hepatic FXR-LDLR/A...
Published 2025“…Additionally, the RPL combination modulated bile acids profiles, leading to an increased proportion of hyodeoxycholic acid (HDCA) and a decreased level of omega-muricholic acid (ω-MCA). …”
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15462
The Natural Anticancer Agent Plumbagin Induces Potent Cytotoxicity in MCF-7 Human Breast Cancer Cells by Inhibiting a PI-5 Kinase for ROS Generation
Published 2012“…In MCF7 human breast cancer cells, plumbagin significantly decreased the level of a human ortholog, 1, 4-phopshatidylinositol 5-kinase (PI5K)-1B, of yeast its3, and knockdown of PI5K-1B using siPI5K-1B increased the ROS level and decreased cell viability. …”
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15463
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15464
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15465
Patch-clamp recording of SW480 and SW620 cells.
Published 2014“…The currents were recorded at a holding potential of 0 mV followed by pulsing voltages between ±100 mV in steps of 20 mV. …”
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15466
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15467
DNA Methylation in <i>Cosmc</i> Promoter Region and Aberrantly Glycosylated IgA1 Associated with Pediatric IgA Nephropathy
Published 2015“…After treatment with IL-4, the levels of <i>Cosmc</i> DNA methylation and aberrantly glycosylated IgA1 in IgAN lymphocytes were remarkably higher than the other two groups (<i>P</i><0.0001) with more markedly decreased Cosmc mRNA content (<i>P</i><0.0001). …”
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15468
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15469
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15470
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15471
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15472
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15473
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15474
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15475
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15476
Supplementary Material for: 5-Hydroxytryptamine 1A and 2B Serotonin Receptors in Neurite Outgrowth: Involvement of Early Growth Response Protein 1
Published 2013“…Acetylcholine may also activate transcription factors such as early growth response protein 1 (EGR-1), which plays a role in neurite extension. N18TG2 neuroblastoma cells (which do not produce neurotransmitters and constitutively express muscarinic acetylcholine receptors) were transfected with constructs containing the cDNA for choline acetyltransferase, 5-hydroxytryptamine 1A (5-HT<sub>1A</sub>) and 5-HT<sub>2B</sub> serotonin receptors to study acetylcholine and serotonin interplay in neurite outgrowth. 5-HT<sub>1A</sub> receptor stimulation causes a decrease in EGR-1 levels and inhibition of neurite outgrowth; 5-HT<sub>2B</sub> stimulation, however, has no effect. …”
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15477
Threshold level of Δ<em>T</em><sub>g</sub> leading to significant local changes in water resources (a) and terrestrial ecosystems (b)
Published 2013“…No population change is assumed here (see figure S5 available at <a href="http://stacks.iop.org/ERL/8/034032/mmedia" target="_blank">stacks.iop.org/ERL/8/034032/mmedia</a>for maps including population scenarios). …”
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15478
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15479
Image5_The Ribosomal Protein L5 Functions During Xenopus Anterior Development Through Apoptotic Pathways.TIFF
Published 2022“…Investigating the molecular mechanisms underlying Rpl5 function revealed a more than additive effect between either loss of function of Rpl5 and loss of function of c-Myc or loss of function of Rpl5 and gain of function of Tp53, suggesting a common signaling pathway of these proteins. …”
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15480
Table_1_The Frequency of V122I Transthyretin Mutation in a Cohort of African American Individuals With Bilateral Carpal Tunnel Syndrome.XLSX
Published 2022“…Up to 47% of patients with the V122I hATTR cardiomyopathy had a history of carpal tunnel syndrome (CTS). …”