DataSheet_2_A cyclic peptide-based PROTAC induces intracellular degradation of palmitoyltransferase and potently decreases PD-L1 expression in human cervical cancer cells.docx by Yu-Ying Shi (15975992)

“…Introduction<p>Our previous research has found that degradation of palmitoyltransferase in tumor cells using a linear peptide PROTAC leads to a significant decrease in PD-L1 expression in tumors. …”

DataSheet_1_A cyclic peptide-based PROTAC induces intracellular degradation of palmitoyltransferase and potently decreases PD-L1 expression in human cervical cancer cells.docx by Yu-Ying Shi (15975992)

“…Introduction<p>Our previous research has found that degradation of palmitoyltransferase in tumor cells using a linear peptide PROTAC leads to a significant decrease in PD-L1 expression in tumors. …”

Ade decreases cell viability and induces cell death. by Shujue Li (466324)

Antineoplastic Effects of siRNA against TMPRSS2-ERG Junction Oncogene in Prostate Cancer by Giorgia Urbinati (554921)

“…The siRNA against TMPRSS2-ERG fusion variant IV showed the highest anti-proliferative effects: Significantly decreased cell viability, increased cleaved caspase-3 and inhibited a cluster of anti-apoptotic proteins. …”

Calyculin A-induced decrease of tyrosine-monophosphorylated ERK2 at high cell density. by Noriyuki Kawabata (3391739)

Effects of siRNA TMPRSS2-ERG on ERG protein expression and cell viability. by Giorgia Urbinati (554921)

“…<p>VCaP cells were transfected for 24h, 48h and 72h with 50 nM of siRNAs TMPRSS2-ERG III (1, 2, 3), siRNAs TMPRSS2-ERG IV (1, 2), siRNA against ERG wild type or siRNA Control. …”

VGB decreased activation of the mTOR pathway in vivo. by Bo Zhang (6559)

Decreased fibrin deposition in hypoxic C3−/− mice. by Eileen M. Bauer (337320)

MPI knockdown decreases migration of human glioblastoma cells. by Aurélie Cazet (644004)

Juvenile demyelination leads to a substantial decrease in potassium currents in PV interneurons of the PFC. by Sara Hijazi (21656615)

“…Scale: 500 pA, 100 ms. <b>B</b>. I–V curves showing a significant decrease in Kv amplitude in PV interneurons from mice that underwent juvenile demyelination. …”

Memory defects, decreased anxiety, and increased social interaction. by Annette E. Rünker (195285)

“…NOR performance at the 4-hr retention interval did not differ from chance (50%) across the genotypes. (C) Spontaneous alternation test of working memory revealed a sex-specific deficit in working memory performance in <i>Sema6A^−/−</i> males (n = 8), as indicated by a decrease in percent alternation, relative to controls (n = 10; p<0.01). …”

Growth on stiff substrate results in mild lifespan extension but a decrease in organismal health. by Maria Oorloff (19658113)

ATRA improved vimentin organization and decreased its expression. by Carmen Retana (479628)

Que decreases the number of infiltrating T cells in spinal cord. by Feng Mei (143817)

“…<b>E–G</b>: CD8⁺ cells display a similar decrease after Que treatment (N = 5, *, <i>p<</i>0.05), but the overall extent of CD8⁺ cells detected was much less than that of CD4⁺ cells. …”

Trehalose decreased PAN-induced apoptosis in human podocytes. by Yu-Lin Kang (663806)

“…<p>Podocyte were treated with PAN (30 µg/ml) or/and Trehalose (50 mM) for 48 h. (<b>A</b>) Trehalose induced autophagy in PAN-treated human podocytes. …”

Low concentrations of siRNA TMPRSS2-ERG III and IV impair TMPRSS2-ERG oncogene and oncoprotein levels but not cell viability. by Giorgia Urbinati (554921)

“…<p>VCaP cells were transfected for 72h from 2.5 nM to 50 nM with siRNA TMPRSS2-ERG III, siRNA TMPRSS2-ERG IV or siRNA Control. …”

Klotho decreased the expression of GRP78 in mouse heart. by Shuang Song (457799)

Klotho decreased the expression of HSP47 in mouse heart. by Shuang Song (457799)

Resveratrol decreased intracellular levels of R5P. by Mohd Askandar Iqbal (324124)

“…Approximately 20–25% decrease in intracellular levels of R5P in HeLa and HepG2 was observed upon 50 µM resveratrol treatment. …”

Astrocytic AQP4 is decreased in aged cortical astrocytes. by Ileana Soto (531878)

“…<p>(A) AQP4 immunoreactivity (blue) and protein levels (B) are significantly decreased in the aged cortex. …”