Proliferation defects in Opa1 depleted type II NB lineages are suppressed by overexpression of Drp1^SD. by Dnyanesh Dubal (12085942)

“…<p>A,C-E: Representative confocal images of type II NB lineages show reduced pH3 positive mature INPs (A) in <i>opa1</i> RNAi while increase in <i>marf</i> RNAi expressed with <i>pnt</i>-Gal4, mCD8-GFP in the type II NB lineage. …”

Depletion of Opa1 shows increased ROS levels in the type II NB lineage. by Dnyanesh Dubal (12085942)

Opa1 and Marf depletion leads to fragmented mitochondria and overexpression of Drp1^SD leads to clustered mitochondria in type II NBs. by Dnyanesh Dubal (12085942)

Inhibition of ABCG2 decreases SP cells, but not sphere-forming ability. by Noriko Kawai (6694010)

Suppression of endogenous human TRAM expression decreases R848 mediated <i>CCL5</i> and <i>IFN-β</i>, but not <i>TNF-α</i> expression. by Enda Shevlin (628477)

a-c: Bone marrow (BM) EPO receptor (EPO-R) decreases in uremic anemia rats. by Daniel Landau (440830)

“…<p>BM EPO-R protein (depicted as percentage of actin-corrected concentration) is unchanged in 7 day-bled rats Vs controls (Fig. 4a). Contrary to that BM EPO-R protein decreases in uremic (4 weeks after 5/6 nephrectomy) rats (Fig. 4b). …”

Decreased transcription of <i>prs</i> results in decreased growth. by Javiera Norambuena (137228)

Interaction of eIF5a with mitochondrial dynamics–related proteins. by Dong Ma (584680)

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eIF5a interacts with Mfn1 and preserves mitochondrial integrity. by Dong Ma (584680)

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NAC suppresses Ang II–induced mitochondrial fission in mouse VSMCs. by Dong Ma (584680)

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Effect of eIF5a and Mfn1 expression on mitochondrial morphology. by Dong Ma (584680)

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Analysis of relative fluorescence intensity. by Dong Ma (584680)

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The effect of Mdivi-1 administration on cell apoptosis in vivo. by Dong Ma (584680)

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VSMCs were stimulated with Ang II (100 nmol/L) for the indicated times. by Dong Ma (584680)

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Klf5 expression is down-regulated in the ruptured human and experimental AAA. by Dong Ma (584680)

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Analysis of human aneurysmal and normal aortic tissues. by Dong Ma (584680)

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Mitochondrial morphology assay. by Dong Ma (584680)

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SMC-specific knockout of Klf5 (smcKlf5^−/−) exacerbates the progression of Ang II–induced AAA by facilitating ROS formation. by Dong Ma (584680)

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The correlation of the mitochondrial dynamics–related genes with Klf5 in mouse VSMCs. by Dong Ma (584680)

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Numerical raw data. by Dong Ma (584680)

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