Table_1_miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer’s Patients.XLSX by Diana J. Cha (8041226)

“…ROC analysis indicated that measurement of miR-132-3p in neurally-derived plasma EVs showed good sensitivity and specificity to diagnose AD, but did not effectively separate individuals with AD-MCI from controls. Moreover, when we measured the levels of a related miRNA, miR-212, we found that this miRNA was also decreased in neural EVs from AD patients compared to controls. …”

DataSheet_1_Selective miRNA inhibition in CD8+ cytotoxic T lymphocytes enhances HIV-1 specific cytotoxic responses.zip by Nadia Madrid-Elena (13861295)

“…When we transfected ex vivo CD8⁺ T cells from progressors with a synthetic miR-10a-5p inhibitor, miR-10a-5p levels decreased in 4 out of 6 progressors, correlating with an increase in HIV-specific cytotoxic responses. …”

Effect of AP-2 depletion on the formation of clathrin-coated structures at the plasma membrane of BSC1 cells. by Emmanuel Boucrot (249080)

“…The central panels are snapshots and the right panels are kymographs from representative time series recorded every 2 s (500 ms exposures) for 360 s from the adherent (bottom) surface of the cells. …”

Gal-3 is upregulated in hypoxia in NG97ht cells. by Rafael Yamashita Ikemori (698128)

“…In the treatment of the protein extracts with AP, there was a decrease in isoforms 2 and 3 compared to control samples mainly in cells exposed to normoxia. …”

Mechano–polarity feedback induces spontaneous and robust cell shape change and tissue deformation. by Fu-Lai Wen (11798016)

“…<p>(A) The deviation of apical domain (<i>ℓ</i>_domain) from its homeostatic size () following a decrease (<i>P</i>_<i>total</i> = 0.9) of total concentration of <i>P</i> plotted as a function of time (top) with the corresponding time evolution of <i>ψ</i> and <i>L</i> normalized by their initial values (bottom). …”

Prevalence of vincristine induced-peripheral neuropathy among Sudanese cancer patients by Imam, Ethar Abdelmageed

“…Healthcare professionals need some understanding regarding medical management that may decrease occurrence of neuropathy and a better planning and implementing special care for patients at risk.…”
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Cellular density effect on the cytoskeleton contribution to E-[c(RGDfK)2] and iRGD internalization. by Damien Moncelet (384264)

“…Treatment with colchicine induced a strong decrease of E-[c(RGDfK)2] and iRGD uptakes. …”

Figure S1 - SUMOylation Regulates the Transcriptional Repression Activity of FOG-2 and Its Association with GATA-4 by José Perdomo (114665)

“…Co-transfection of the indicated SUMO E3 ligases did not increase FOG-2 SUMOylation (lanes 2 to 5, right panel). In fact there was a decrease in FOG-2 SUMOylation in the presence of Ubc9 (lane 7, left panel) or E3 ligases (lanes 2 to 5, right panel). …”

EBNA1 can self-associate through its UR1 domain. by Siddhesh Aras (263042)

“…The scale bars indicate a length of 10 microns. The fraction of fluorescent cells observed under each condition in five independent measurements is shown along with the standard deviation. …”

DataSheet_1_Effects of diet and temperature on the fatty acid composition of the gammarid Gammarus locusta fed alternative terrestrial feeds.docx by Alberto Ribes-Navarro (9973753)

“…The temperature had no effect on biomass, although high temperature (20°C) resulted in a decrease in survival. The effects of temperature on the gammarid fatty acids were not evident, with diet being the main modulator of the profiles. …”

C57BL substrain differences in generalized seizure thresholds. by Sridhar B. Kadiyala (529914)

“…<p>The latency to a generalized seizure (generalized seizure threshold (GST)) on each seizure trial was determined for 5 C57BL substrains (n = 12 mice/substrain: 10SNJ, 10J, 6J, 6NJ, and KSJ) by exposure to 10% flurothyl during eight induction trials followed by a 28-day rest period and a single flurothyl retest. …”

Rain-Shelter Cultivation Modifies Carbon Allocation in the Polyphenolic and Volatile Metabolism of <i>Vitis vinifera</i> L. Chardonnay Grapes by Yuan Gao (159945)

“…In addition, the rain-shelter cultivation significantly enhanced the synthesis of fatty acid-derived volatiles, isoprene-derived terpenoids and amino acid-derived branched-chain aliphatics, but led to a decrease in the accumulation of isoprene-derived norisoprenoids and amino acid-derived benzenoids. …”

Distribution patterns of Platycodon grandiflorus from the last inter-glacial period to the future by ecological niche modeling by Chunjiao Li (19159480)

“…The results indicated: (1) The species' distribution strongly correlates with environmental variables, particularly bio13, prec07, prec09 and tmin07, whose cumulative value of percent contribution was 78.5%; (2) The centroids of potential geographic distribution during the LIG, LGM, and MH periods were situated further westward compared tothe present distribution, with substantial contraction observed in highly suitable habitats throughout these historical periods; (3) Under present climatic conditions, the overall suitable habitat encompasses4,185,964 km2, withhighly suitable habitats constitutingone-third of this expanse, predominantlyconcentrated in central, southern, and northeasternChina; (4) Future climate change scenarios predict that the total suitable habitat will expand to varying degrees (7% increase on average), albeit with potential reductions in highly suitable areas (3% decrease on average); (5) The distribution of P. grandiflorus is likely to move towards higher latitudes in the future due to climate changes. …”

SPDEF and Foxm1 are inversely correlated in prostate carcinogenesis. by Xin-Hua Cheng (154368)

“…<p><b>A</b>. In transgenic <i>TRAMP/SPDEF OE</i> mice, over-expression of SPDEF in prostate epithelial cells decreased Foxm1 mRNA (left panel) and protein (right panels) in prostate tumors. …”

CRF-induced anxiety-like behavior is mediated by the dynorphin/KOR system. by Michael R. Bruchas (255614)

“…<p><b><i>A</i></b>, CRF injection (1 µg, i.c.v., 30 min prior to assay) produced a significant anxiety-like effect (decrease in % open arm time) in the elevated plus maze (EPM) compared with saline injected controls. …”

CStS recapitulate MSNs degeneration observed in R6/2 mouse model. by Catia C. Proenca (431486)

“…Neurodegeneration is observed as a decrease in marker intensity. F) Left: quantification for the ratio of striatal NeuN and DAPI positive nuclei in WT and R6/2 slices at DIV21. …”

Additional file 2 of Facilitation of colonic T cell immune responses is associated with an exacerbation of dextran sodium sulfate–induced colitis in mice lacking microsomal prostag... by Fumiaki Kojima (11905683)

“…A significant decrease in food uptake was observed in mPGES-1−/− mice during DSS administration over 7 days, indicating severe symptoms of colitis in mPGES-1−/− mice. …”

Erratum: Pharmacokinetics, Pharmacodynamics, and Safety of Single-Dose Rivaroxaban in Chronic Hemodialysis by Dias C. (4162003)

“…In 8 subjects with ESRD, a 15-mg dose of rivaroxaban was administered 2 ± 0.5 h before a hemodialysis session and repeated 7-14 days later at 3 h after a 4-h hemodialysis session. …”

Both SecTRAPs and TrxR1 are efficient in reducing juglone and thereby produce superoxide. by Karin Anestål (377878)

“…In (D), the reduction of juglone (5 µM) catalyzed by 10 nM SecTRAP (truncated TrxR1, left panel) or full-length TrxR1 (right panel) is shown following the consumption of NADPH (initial concentration 250 µM) by the decrease in absorbance at 340 nm (open symbols). …”

Pituitary Adenylate Cyclase Activating Peptide (1-38) and its analog (Acetyl-[Ala15, Ala20] PACAP 38-polyamide) reverse methacholine airway hyperresponsiveness in rats by Mounira Tlili (12847046)

“…Male Wistar rats were divided randomly into five groups. Groups 1 and 2 inhaled respectively aerosols of saline or increasing doses of MeCh (0.5, 1, 2.12, 4.25, 8.5, 17, 34 and 68mg/L). …”