DNMT3L was found within the adult testis and mature sperm. by Natasha M. Zamudio (225855)

“…Results are presented as means ± SEM. <b>*</b> Indicates a statistically significant decrease in relative intensity of DNMT3L with a p≤0.05.…”

Spontaneous replay switches between multiple environments. by Bastian Pietras (14295598)

“…<p>In the (A) mesoscopic and (B) microscopic ring-attractor network storing multiple environments, metastable replay dynamics spontaneously emerge due to finite-size fluctuations when decreasing the population size from <i>N</i> = 500 (orange/red in panels i) to <i>N</i> = 50 (blue/black) per unit. …”

SEA binds DC-SIGN and can block <i>trans</i>-infection of CD4 T-lymphocytes but not <i>cis</i>-infection. by Emily EIM Mouser (7348559)

“…<b>(D)</b> SEA’s effect on <i>trans</i>-infection was determined by pre-incubating Raji DC-SIGN cells with 1μg/ml SEA for 2h and subsequently adding SF162 (TCID₅₀ 5000) or LAI (TCID₅₀ 500). Viral outgrowth in Raji DC-SIGN—CD4⁺ T-lymphocyte co-cultures was monitored through measuring p24 levels in culture supernatant. …”

Combined intervention of swimming plus metformin ameliorates the insulin resistance and impaired lipid metabolism in murine gestational diabetes mellitus by Liping Huang (315281)

“…Swimming or metformin intervention slightly or moderately improves hyperglycemia, insulin sensitivity and lipid metabolism both in liver and skeletal muscle from GDM mice, while combined therapy of swimming plus metformin markedly ameliorated hyperglycemia (FPG, decreased by 22.2–59.5% from G10 to G18 versus DC group), insulin sensitivity (2.1 and 2.8 fold increase, respectively, in AKT activity versus DC group) and <i>de novo</i> lipogenesis (3.2 and 7.0 fold decrease, respectively, in ACC activity, and 1.94 and 5.1 fold decrease, respectively, in SREBP2 level, versus DC group) both in liver and skeletal muscle from GDM mice. …”

AZ10606120 treatment significantly increased cytotoxicity and reduced cell number in a dose-dependent manner. by Matthew Drill (22258391)

“…Cell numbers were significantly decreased in cells after treatment with AZ10606120 (50µM) compared to both temozolomide (TMZ; 50µM) treatment and untreated controls. …”

Trend direction for the diurnal temperature range (DTR) using the Mann–Kendall (MK) test. by Heli Lu (516590)

Supplementary Material for: The impact of age and body composition on the agreement between estimated and measured GFR in heart transplant recipients by Hornum M. (16418109)

“…During the first year after HTx, mean weight increased by 4.2 kg (CI:3.2–5.1) followed by an annual decrease of 0.35 kg/year (Cl:-0.05–0.74). mGFR increased by 7.5 ml/min (Cl:3.2–11.8) the first year but was stable hereafter (0.0 ml/min/year CI:-1.0–1.0). …”

Down-regulation of PCNA increases the number of oocytes by alleviating the apoptosis of oocytes in fetal mouse ovaries. by Bo Xu (233514)

“…(<b>B</b>) The number of oocytes decreased gradually with time of transfection in PCNA RNAi or control ovaries, while the decrease in control ovaries was more dramatic than in PCNA RNAi ovaries. …”

Investigating the expression of several bone markers in mineralizing 4T1 cells using real-time RT-PCR. by Rachel F. Cox (148193)

“…Each point represents the mean +/− SEM, n = 3, two-way ANOVA. OC (osteogenic cocktail) = 50 µg/ml ascorbic acid and 10 mM β-glycerophosphate. …”

Apc2 expression co-localizes with EB1 in growing axon and cell bodies of Eagle neurons and is reduced in <i>brat</i> mutant embryos. by Elise Arbeille (5058602)

“…(H) and (H’) <i>brat</i> homozygous mutant embryos, show a decrease of the GFP signal intensity to 50% in cell bodies and 25% in axons, reflecting a reduction of the Apc2 transgene expression. …”

Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies by Hadith Tangestani (6202022)

“…A systematic search up to October 2017 was done via PubMed and Scopus search engines. To pool mean differences, random-effects model (the DerSimonian-Laird estimator) was used. …”

Efficacy of topical brinzolamide in children with retinal dystrophies by Brittni A. Scruggs (511698)

“…For treated patients, average visual acuity (LogMAR) ± standard error of the mean improved from 0.5 ± 0.04 pre-treatment to 0.3 ± 0.1 at the second endpoint, 50.2 ± 7.3 months after treatment initiation.…”

Propagation of GABA-induced hyperpolarization at the axon regulates AP generation. by Yang Xia (104600)

“…Right, group data showing a decrease in the mean frequency of APs after GABA iontophoresis at the axon trunk. **, P<0.01, paired t-test. …”

Organismal Phenotypes in Chimeric Mice by Dennis C Ko (380536)

“…For wild-type and <i>npc1^−/−</i> homozygous mice, the curve shown is the mean weight from three to four mice. A progressive decrease in weight of <i>npc1</i> mice begins to show around 7 wk. …”

Modulation of endocannabinoid levels by R-flrubiprofen in microglial cells (EOC20) and tissue. by Philipp Bishay (248901)

“…Vehicles 10% or 50% DMSO did not produce changes of the core temperature as compared to phosphate buffered saline and were summarized. …”

DtpT proteoliposomes require both a valid substrate and potential gradient in order to drive proton-coupled transport. by Imran Khan (109715)

“…(C) Validation of pyranine assays in DtpT liposomes. Curves show the mean of three replicates normalised to the initial fluorescence signal (t = -50 s). …”

Relationship between cold sensitivity and inhibitor sensitivity of primary HIV-1 envelope glycoproteins. by Hillel Haim (216672)

“…<p>(<b>A</b>) Sensitivity to cold-induced inactivation of viruses containing envelope glycoproteins derived from a standardized panel of primary HIV-1 isolates, including transmitted/founder HIV-1. Data represent the mean incubation time on ice required for a 25% decrease from initial infectivity (IT25) in an experiment performed with three replicate samples. …”

Synergistic effect of HDACi and EZH2i on schistosomula viability. by Letícia Anderson (2543926)

“…<p>(A) Schistosomula were treated with drugs in five different conditions: control with vehicle (DMSO + Ethanol); 20 μM GSK343; 50 μM GSK343; 1 μM TSA and 1 μM TSA + 20 μM GSK343. …”

Rhodopsin characterization in adult WT and <i>Fmr1</i> KO mice retinas. by Rafaëlle Rossignol (621196)

“…Rhodopsin protein was decreased by 37% (*pFmr1 KO mice compared to WT retinas. …”

Foxm1 expression during heart development. by Craig Bolte (299486)

“…Mean±SEM was determined from 5 random sections at E14.5 and P7 with 3 hearts in each group. qRT-PCR of total heart RNA demonstrated a decrease in Foxm1 mRNA from E14.5 to P20 and Foxm1 mRNA was undetectable in the adult heart (R). …”