<i>Borassus flabellifer</i> Linn haustorium methanol extract mitigates fluoride-induced apoptosis by enhancing Nrf2/Haeme oxygenase 1 –dependent glutathione metabolism in intestina... by Joice Tom Job (10813835)

“…The total polyphenols and total flavonoids present in BHE were estimated to be 39.67 ± 5.14 mg gallic acid equivalent/g extract and 8.59 ± 0.74 mg quercetin equivalent. In cultured intestinal epithelial cells (IEC-6), sodium fluoride exposure-induced apoptosis mediated through antioxidant enzyme inhibition and subsequent oxidative damages. …”

Stress-reactivity measured by whole-body cortisol concentration of zebrafish 6-month-old adults. by Matteo Baiamonte (721514)

“…Means ± SE, 9 batches of animals per group. *<i>P</i><0.05 **<i>P</i><0.01 “t” test and ANOVA.…”

Effects of exercise on circulating tumor cells among patients with resected stage I-III colon cancer by Justin C. Brown (185942)

“…Over six months, significant decreases in CTCs were observed in the low-dose (−1.34±0.34; <i>P</i><0.001) and high-dose (−1.18±0.40; <i>P</i> = 0.004) exercise groups, whereas no significant change was observed in the control group (−0.59±0.56; <i>P</i> = 0.292). …”

Black bear (<i>Ursus americanus</i>) isotopic niches and corresponding isotopic niche density plots. by Diana J. R. Lafferty (821083)

“…Black dots correspond to means and decreasing bar widths represent 50%, 75% and 95% Bayesian credible intervals. …”

ORF63 does not affect STAT2 activation but promotes IRF9-degradation. by Marieke C. Verweij (357813)

Image_4_The Association of Real-World CA 19-9 Level Monitoring Patterns and Clinical Outcomes Among Patients With Metastatic Pancreatic Ductal Adenocarcinoma.tif by Ben George (64738)

“…Patients with decreasing/stable CA 19-9 during treatment experienced longer survival than patients who experienced an increase in CA 19-9 levels [1L: 10.9 months (10.5 – 11.3) vs. 5.4 months (5.1 – 5.9), p < 0.0001; 2L: 8.2 months (7.7 – 8.5) vs. 4.3 months (4.1 – 4.7), p < 0.001; 3L: 7.5 months (6.6 – 9.2) vs. 3.7 months (3.4 – 4.3), p < 0.001].…”

Image_5_The Association of Real-World CA 19-9 Level Monitoring Patterns and Clinical Outcomes Among Patients With Metastatic Pancreatic Ductal Adenocarcinoma.tif by Ben George (64738)

“…Patients with decreasing/stable CA 19-9 during treatment experienced longer survival than patients who experienced an increase in CA 19-9 levels [1L: 10.9 months (10.5 – 11.3) vs. 5.4 months (5.1 – 5.9), p < 0.0001; 2L: 8.2 months (7.7 – 8.5) vs. 4.3 months (4.1 – 4.7), p < 0.001; 3L: 7.5 months (6.6 – 9.2) vs. 3.7 months (3.4 – 4.3), p < 0.001].…”

Image_3_The Association of Real-World CA 19-9 Level Monitoring Patterns and Clinical Outcomes Among Patients With Metastatic Pancreatic Ductal Adenocarcinoma.tif by Ben George (64738)

“…Patients with decreasing/stable CA 19-9 during treatment experienced longer survival than patients who experienced an increase in CA 19-9 levels [1L: 10.9 months (10.5 – 11.3) vs. 5.4 months (5.1 – 5.9), p < 0.0001; 2L: 8.2 months (7.7 – 8.5) vs. 4.3 months (4.1 – 4.7), p < 0.001; 3L: 7.5 months (6.6 – 9.2) vs. 3.7 months (3.4 – 4.3), p < 0.001].…”

Image_1_The Association of Real-World CA 19-9 Level Monitoring Patterns and Clinical Outcomes Among Patients With Metastatic Pancreatic Ductal Adenocarcinoma.tif by Ben George (64738)

“…Patients with decreasing/stable CA 19-9 during treatment experienced longer survival than patients who experienced an increase in CA 19-9 levels [1L: 10.9 months (10.5 – 11.3) vs. 5.4 months (5.1 – 5.9), p < 0.0001; 2L: 8.2 months (7.7 – 8.5) vs. 4.3 months (4.1 – 4.7), p < 0.001; 3L: 7.5 months (6.6 – 9.2) vs. 3.7 months (3.4 – 4.3), p < 0.001].…”

Image_2_The Association of Real-World CA 19-9 Level Monitoring Patterns and Clinical Outcomes Among Patients With Metastatic Pancreatic Ductal Adenocarcinoma.tif by Ben George (64738)

“…Patients with decreasing/stable CA 19-9 during treatment experienced longer survival than patients who experienced an increase in CA 19-9 levels [1L: 10.9 months (10.5 – 11.3) vs. 5.4 months (5.1 – 5.9), p < 0.0001; 2L: 8.2 months (7.7 – 8.5) vs. 4.3 months (4.1 – 4.7), p < 0.001; 3L: 7.5 months (6.6 – 9.2) vs. 3.7 months (3.4 – 4.3), p < 0.001].…”

Pulmonary Abnormalities in Mice with Paracoccidioidomycosis: A Sequential Study Comparing High Resolution Computed Tomography and Pathologic Findings by Damaris Lopera (246539)

“…The experimental design used decreases the need to sacrifice a large number of animals, and serves to monitor treatment efficacy by means of a more rational approach to the study of human lung disease.…”

Image 1_Relationship between triglyceride glucose-body mass index baselines and variation with future cardiovascular diseases risk in the middle-aged and elderly individuals.jpeg by Junpeng Qiao (11726521)

“…After adjusting for potential confounding factors, compared to participants with consistently low TyG-BMI levels, those with moderate TyG-BMI levels and a slowly increasing trend had an HR of 1.27 (95% CI 1.10-1.47), while those with the highest TyG-BMI levels and a slowly decreasing trend had an HR of 1.52 (95% CI 1.26-1.83).…”

Image 2_Relationship between triglyceride glucose-body mass index baselines and variation with future cardiovascular diseases risk in the middle-aged and elderly individuals.jpeg by Junpeng Qiao (11726521)

“…After adjusting for potential confounding factors, compared to participants with consistently low TyG-BMI levels, those with moderate TyG-BMI levels and a slowly increasing trend had an HR of 1.27 (95% CI 1.10-1.47), while those with the highest TyG-BMI levels and a slowly decreasing trend had an HR of 1.52 (95% CI 1.26-1.83).…”

Table 1_Relationship between triglyceride glucose-body mass index baselines and variation with future cardiovascular diseases risk in the middle-aged and elderly individuals.docx by Junpeng Qiao (11726521)

“…After adjusting for potential confounding factors, compared to participants with consistently low TyG-BMI levels, those with moderate TyG-BMI levels and a slowly increasing trend had an HR of 1.27 (95% CI 1.10-1.47), while those with the highest TyG-BMI levels and a slowly decreasing trend had an HR of 1.52 (95% CI 1.26-1.83).…”

Figure 2 from Auranofin Synergizes with Cisplatin in Reducing Tumor Burden of NOTCH-Dependent Ovarian Cancer by Robert J. Lake (22408833)

“…ED25, ED50, ED75, and ED100 = 25%, 50%, 75%, and 100% inhibition of viability, respectively. …”

Other calpain inhibitors in RGC damage in hypoxic retina. by Emi Nakajima (21703141)

“…<p>(A) The IC50 of calpain inhibitors against calpains 1 and 2 in vitro.…”

Social interaction involves CeA neurons. by Karolina Rojek-Sito (13197192)

“…All the data are shown as the mean ± SEM, and dots represent individual data points, * <i>p</i> < 0.05, ** <i>p</i> < 0.01, *** <i>p</i> < 0.001. …”

<i>pals-17</i> mutant phenotypes are fully <i>pals-16</i>-dependent. by Vladimir Lažetić (5047592)

“…<p>(A, B) <i>pals-16</i> RNAi decreases <i>pals-5</i>p::GFP expression in <i>pals-17 pals-20</i> mutants. …”

CNNM4 but not SLC41A1 stimulates TRPM7-mediated divalent cation entry. by Zhiyong Bai (259036)

“…The fluorescence intensity of the cells (mean of 50 cells) were quantified for each time point. …”

Effects of the Pgp inhibitor tariquidar (TQ; 0.5 µM) in three functional assays, in which alterations in Pgp efflux are indirectly measured by determining intracellular concentrati... by Andreas Noack (519906)

“…In the absence of doxycycline (open columns), tariquidar significantly increased Rho123 accumulation (i.e., decreased Rho123 efflux) by only about 15%. In the presence of doxycycline, accumulation of Rho123 was only about 50% of that under doxycycline-off conditions, which was completely counteracted by tariquidar. …”