Comparison of the Simulated Activities of PI3K, Membrane-Bound PTEN, and the Resulting Behavior of PIP₃ (Composite Screenshot) by Martin Meier-Schellersheim (63389)

“…<p>Stimulation of a cell in a 2:1 cAMP gradient (mean concentration 500 nmol) leads to a rapid 3-fold increase in the membrane proximal activity of PI3K (green) and to a loss of membrane-bound PTEN (blue; tracked as GFP-PTEN in real cells). …”

AP-1 knockdown potentiates the effect of AP-3 knockdown on regulated secretion. by Daniel W. Sirkis (463685)

“…*p<0.05; **p<0.01; ***p<0.001 (Newman-Keuls post-hoc test; n = 4 transfections). The data show mean values, and error bars indicate s.e.m.</p>…”

Cytosolic SYT isoforms interact with actin. by Jaehong Kim (261471)

“…The data shown are the mean±SEM of the normalized densities from 3 independent experiments. …”

Spike rate ratio was lower in <i>rd10</i> than in wild type retina. by Christine Haselier (576439)

“…Each mean is marked by a cross. B: Data from PNW20 wild type and <i>rd10</i> mice are shown. …”

Autophagic machinery is involved in cross-over endocytosis. by Nora Gehne (4357123)

“…Mean±SEM, for each group n>50. *p<0.05, **p<0.01, ***p<0.001; two-sided t test.…”

MMR activities in the APE and hMSH6 expressing cells by In-Youb Chang (10654)

“…The repair efficiency was calculated as the percentage of decrease in the mixed-color colonies. The values are a mean ± SD from three separate experiments. …”

Spatial-temporal variation in litterfall in seasonally dry tropical forests in Northeastern Brazil by V. F. P. Araújo (7141901)

“…Eight sampling points were randomly chosen at each site, and two 1 m2 collectors were installed 50 m apart from each other. The collected material was sorted, dried and weighed. …”

Hypothesized vs. actual direction of responses to increasing levels of independent climatic and environmental variables based on conditions during the leaf and wood decomposition (... by Beth A. Middleton (4432957)

“…<p><b>Increase or decrease in response is depicted by “↓” vs. “↑”, respectively.…”

The viability and morphology of IL-13- or IL-13+ cell cultures. by Andrea Stadnikova (3929546)

“…Cell viability data are presented in a vertical scatter plot graph with line indicating mean. *P < 0.05, ***P ≤ 0.001. Blue asterisks indicate significant decrease of viability in P1d1 IL-13- or P1d1 IL-13+ group vs. …”

Factor of change of pO (ΔpO) segregated with respect to the initial median pO by Bernardino Clavo (3925)

“…The boxes show the 25%–75% inter-quartile interval, which includes the 50% values. The horizontal lines in the boxes represent the median and the * represents the mean of ΔpO for both groups of tumors at each measurement time-point. …”

Altered TRPV1 staining is observed in DRG obtained from STZ-induced diabetic mice by Reddy M Pabbidi (44094)

“…Summary graph showing increase in mean gray values of TRPV1 staining (n = 5 sections from 4 mice, p < 0.058) in hyperalgesic DRG and decrease in TRPV1 gray value in hypoalgesic diabetic mice (n = 6 sections from 4 mice, p < 0.05) as compared to control non-diabetic mice. . …”

Table_1_An Item-Level Analysis for Detecting Faking on Personality Tests: Appropriateness of Ideal Point Item Response Theory Models.docx by Jie Liu (15128)

“…The item-level analysis revealed both conscientiousness items (18.8%) and neuroticism items (50.0%) appeared significant shifts on item parameters, suggesting that response pattern changed from honest to faking conditions. …”

Glyphosate alters the composition, but not density, of the <i>A</i>. <i>gambiae</i> midgut microbiota. by Daniel F. Q. Smith (10788903)

“…Error bars represent the mean and ±SD. <b>(B)</b> Glyphosate alters the composition of the mosquito microbiota, leading to decrease of Entereobacteriacae and an increase of <i>Asaia</i> spp. …”

The activity of TRPV1 is dependent on phosphoinositides. by Hae-Jin Kweon (525019)

“…Data are mean ± SEM.</p>…”

Blockade of β₃AR completely restores attenuated HPV in IH rats. by Hisashi Nagai (650547)

“…The tungsten wire in the lower right corner of each image is a reference wire with a diameter of 50 μm. (B, C) Relationship between vessel size and the extent of the pulmonary vasoconstriction (% decrease in vessel diameter) induced in response to acute hypoxia in the N and IH rats treated with or without SR59230A. …”

The effect of cPTIO pre-treatment on cell death rate. by Bushra Ijaz (4353385)

“…<p>Cell death rate as measured in tolerant (a) and sensitive (b) cell cultures after 50uM cPTIO pre-treatment and 100 and 150mM NaCl stress. …”

Pyrvinium inhibits Wnt signaling. by Sarika Saraswati (236578)

“…<p>(<b>A</b>) Pyrvinium inhibits TOPflash activation with an EC₅₀ of ∼10 nM in contrast to the structurally related compound VU-WS211. …”

SS- and AGEs-induced simultaneous increases in proliferation and apoptosis of VSMCs are closely associated with selective activation of three members the MAPK subfamily. by Suning Ping (172755)

“…<p>The cultured quiescent VSMCs were pretreated with DMSO, ERK inhibitor PD98059 (50 μM), JNK inhibitor SP600125 (20 μM), and p38MAPK inhibitor SB202190 (20 μM) for 1 h and then treated with SS and/or AGEs for 1 h and continually cultured for 23 h. …”

Nuclear Quantum Effects in Sodium Hydroxide Solutions from Neural Network Molecular Dynamics Simulations by Matti Hellström (1886893)

“…We find that NQEs have a very small impact on the solvation structure around Na⁺, slightly strengthen the water–water and water–hydroxide hydrogen bonds, and lower the peak positions in the power spectra for the HOH bending and OH stretching modes by about 50 and 100 cm^–1, respectively. Moreover, NQEs significantly lower the proton transfer barriers, thus increasing the proton transfer rates, resulting in an increase of the diffusion coefficient in particular of OH^–, as well as a decrease of the mean residence time of molecules in the first hydration shell around Na⁺ at high NaOH concentrations.…”

Transcriptional downregulation of Bcl-2 is critical to mediate PMC-A induced apoptosis. by Cagri Bodur (282762)

“…The results from at least 3 independent experiments were shown as means ± SD. Difference of mean values between mock and Bcl-2-transfected cells were tested using paired student’s t-test; <b>**</b>P<0.01. …”