Table_3_Inhibition of Rho Kinase by Fasudil Ameliorates Cognition Impairment in APP/PS1 Transgenic Mice via Modulation of Gut Microbiota and Metabolites.XLSX by Yuqing Yan (649254)

“…The metagenomic analysis revealed the abundance of the dominant phyla in all the three groups, including Bacteroidetes (23.7–44%) and Firmicutes (6.4–26.6%), and the increased relative abundance ratio of Firmicutes/Bacteroidetes in ADNS (59.1%) compared to WT (31.7%). In contrast, the Firmicutes/Bacteroidetes ratio was decreased to the WT level in ADF (32.8%). …”

Table_6_Inhibition of Rho Kinase by Fasudil Ameliorates Cognition Impairment in APP/PS1 Transgenic Mice via Modulation of Gut Microbiota and Metabolites.XLSX by Yuqing Yan (649254)

“…The metagenomic analysis revealed the abundance of the dominant phyla in all the three groups, including Bacteroidetes (23.7–44%) and Firmicutes (6.4–26.6%), and the increased relative abundance ratio of Firmicutes/Bacteroidetes in ADNS (59.1%) compared to WT (31.7%). In contrast, the Firmicutes/Bacteroidetes ratio was decreased to the WT level in ADF (32.8%). …”

Table_4_Inhibition of Rho Kinase by Fasudil Ameliorates Cognition Impairment in APP/PS1 Transgenic Mice via Modulation of Gut Microbiota and Metabolites.XLSX by Yuqing Yan (649254)

“…The metagenomic analysis revealed the abundance of the dominant phyla in all the three groups, including Bacteroidetes (23.7–44%) and Firmicutes (6.4–26.6%), and the increased relative abundance ratio of Firmicutes/Bacteroidetes in ADNS (59.1%) compared to WT (31.7%). In contrast, the Firmicutes/Bacteroidetes ratio was decreased to the WT level in ADF (32.8%). …”

Table_2_Inhibition of Rho Kinase by Fasudil Ameliorates Cognition Impairment in APP/PS1 Transgenic Mice via Modulation of Gut Microbiota and Metabolites.XLSX by Yuqing Yan (649254)

“…The metagenomic analysis revealed the abundance of the dominant phyla in all the three groups, including Bacteroidetes (23.7–44%) and Firmicutes (6.4–26.6%), and the increased relative abundance ratio of Firmicutes/Bacteroidetes in ADNS (59.1%) compared to WT (31.7%). In contrast, the Firmicutes/Bacteroidetes ratio was decreased to the WT level in ADF (32.8%). …”

Table_5_Inhibition of Rho Kinase by Fasudil Ameliorates Cognition Impairment in APP/PS1 Transgenic Mice via Modulation of Gut Microbiota and Metabolites.XLSX by Yuqing Yan (649254)

“…The metagenomic analysis revealed the abundance of the dominant phyla in all the three groups, including Bacteroidetes (23.7–44%) and Firmicutes (6.4–26.6%), and the increased relative abundance ratio of Firmicutes/Bacteroidetes in ADNS (59.1%) compared to WT (31.7%). In contrast, the Firmicutes/Bacteroidetes ratio was decreased to the WT level in ADF (32.8%). …”

Image_1_Inhibition of Rho Kinase by Fasudil Ameliorates Cognition Impairment in APP/PS1 Transgenic Mice via Modulation of Gut Microbiota and Metabolites.tif by Yuqing Yan (649254)

“…The metagenomic analysis revealed the abundance of the dominant phyla in all the three groups, including Bacteroidetes (23.7–44%) and Firmicutes (6.4–26.6%), and the increased relative abundance ratio of Firmicutes/Bacteroidetes in ADNS (59.1%) compared to WT (31.7%). In contrast, the Firmicutes/Bacteroidetes ratio was decreased to the WT level in ADF (32.8%). …”

Table_1_Inhibition of Rho Kinase by Fasudil Ameliorates Cognition Impairment in APP/PS1 Transgenic Mice via Modulation of Gut Microbiota and Metabolites.XLSX by Yuqing Yan (649254)

“…The metagenomic analysis revealed the abundance of the dominant phyla in all the three groups, including Bacteroidetes (23.7–44%) and Firmicutes (6.4–26.6%), and the increased relative abundance ratio of Firmicutes/Bacteroidetes in ADNS (59.1%) compared to WT (31.7%). In contrast, the Firmicutes/Bacteroidetes ratio was decreased to the WT level in ADF (32.8%). …”

Gender-Specific Effects of Genetic Variants within Th1 and Th17 Cell-Mediated Immune Response Genes on the Risk of Developing Rheumatoid Arthritis by Rafael Cáliz (452151)

“…In men, carriers of the <i>DC-SIGN</i>_rs2287886A allele had an increased risk of RA (OR = 1.70, 95%CI 1.03–2.78), whereas carriers of the <i>DC-SIGN</i>_rs4804803G had a decreased risk of developing the disease (OR = 0.53, 95%CI 0.32–0.89). …”

Data_Sheet_1_Secular trends in the prevalence of meeting 24-hour movement guidelines among U.S. adolescents: evidence from NHANES 2007–2016.docx by Xue-qing Liu (18293836)

“…Compliance with PA and SB recommendations among adolescents has decreased over time, from 72.5% (65.9% to 79.2%) to 64.2% (57.4% to 70.9%) for PA, and from 59.0% (49.6% to 68.4%) to 46.6% (37.8% to 55.5%) for SB, respectively, from 2007–2008 cycle to 2015–2016 cycle. …”

Data_Sheet_1_Prognostic Impact of Left Ventricular Ejection Fraction in Patients With Moderate Aortic Regurgitation: Potential Implications for Treatment Decision-Making.pdf by Qinghao Zhao (11182500)

“…</p>Methods:<p>In total, 1,211 consecutive patients with moderate AR (jet width, 25–64% of LV outflow tract; vena contracta, 0.3–0.6 cm; regurgitant volume, 30–59 mL/beat; regurgitant fraction, 30–49%; effective regurgitation orifice, 0.10–0.29 cm²) prospectively registered between April and June 2018 at 46 academic hospitals were included. …”

Relationship between periodic patterning and receptive field refinement. by James E. M. Bennett (787674)

“…Purple trace: plot of the mean number of synapses with strength > 0.5 as an indicator of RF size. …”

Mosquito-Disseminated Insecticide for Citywide Vector Control and Its Potential to Block Arbovirus Epidemics: Entomological Observations and Modeling Results from Amazonian Brazil by Fernando Abad-Franch (127663)

“…Mean adult <i>Aedes</i> emergence fell from 1,077 per month (range 653–1,635) at baseline to 50.4 per month during PPF dissemination (range 2–117). …”

MVEC:AoAF interactions are dependent on signaling through ALK5. by Rebecca A. Scott (488956)

“…F-actin is stained with phalloidin-568 (yellow), nuclei are counterstained with Hoechst 33258 (cyan), and MVECs are labeled with CD31 (magenta). Scale bar = 50 μm. In <b>B-F, H-K</b>: data are represented as the mean ± SEM, with <i>n</i> = 3 biological replicates per condition. …”

Tamoxifen induction at E11.5 causes overproduction of oversized, innervated taste buds in <i>ShhCreER</i>^<i>T2</i><i>/Shh</i>^<i>f</i> mutant tongues. by Maha El Shahawy (557888)

“…(<b>E</b>) RT-qPCR analysis for <i>Ptch1</i> relative to <i>Actb</i> (β-actin) in tongues from E13.5 controls (n = 9) and mutants (n = 9). Severely decreased <i>Ptch1</i> levels in the mutant tongues as compared to the controls (<i>P</i> = 0.0000; mean values ± SD). …”

The hypothalamic-pituitary-thyroid axis in TRH deficient mice. by Yasuyo Nakajima (316579)

“…The TSHβ mRNA level in TRH−/− was decreased to about 50% of that in the wild-type, and that of TRH−/−+T4 mice was further decreased to about 10% (n = 3, <i>p<</i>0.01). **, <i>p</i><0.01. …”

Image 1_Enhancing yield and quality: research and practice of agro-forest waste for Lentinus edodes (shiitake mushroom) cultivation.jpg by Hongyan Xu (29047)

“…</p>Results<p>Results showed that the average duration to complete stages 2 and 3 of mycelial growth on 10% KP substrates significantly decreased compared to the OS group by 11.0 and 10.7 days, respectively. …”

Interferon-free therapy with direct acting antivirals for HCV/HIV-1 co-infected Japanese patients with inherited bleeding disorders by Haruka Uemura (4521400)

“…</p><p>Results</p><p>Eighteen (67%) patients had had received interferon-based therapy, and 11 (41%) had compensated cirrhosis. HCV genotypes were GT1a 4 (15%), GT1b 16 (59%), GT1 undetermined 2 (7%), GT2a 1 (4%), GT3a 3 (11%) and GT4a 1 (4%). …”

Consensus Signature Groups systematically characterize patterns of time-dependent microbiota changes in response to infection. by Clara Belzer (596775)

Data_Sheet_1_Trajectories of (Bio)markers During the Development of Cognitive Frailty in the Doetinchem Cohort Study.pdf by M. Liset Rietman (6760496)

“…</p><p>Methods: The Doetinchem Cohort Study is a longitudinal population-based study that started in 1987–1991 in men and women aged 20–59 years, with follow-up examinations every 5 years. …”

Data_Sheet_2_Trajectories of (Bio)markers During the Development of Cognitive Frailty in the Doetinchem Cohort Study.pdf by M. Liset Rietman (6760496)

“…</p><p>Methods: The Doetinchem Cohort Study is a longitudinal population-based study that started in 1987–1991 in men and women aged 20–59 years, with follow-up examinations every 5 years. …”