Image_3_The Association of Real-World CA 19-9 Level Monitoring Patterns and Clinical Outcomes Among Patients With Metastatic Pancreatic Ductal Adenocarcinoma.tif by Ben George (64738)

“…Patients with decreasing/stable CA 19-9 during treatment experienced longer survival than patients who experienced an increase in CA 19-9 levels [1L: 10.9 months (10.5 – 11.3) vs. 5.4 months (5.1 – 5.9), p < 0.0001; 2L: 8.2 months (7.7 – 8.5) vs. 4.3 months (4.1 – 4.7), p < 0.001; 3L: 7.5 months (6.6 – 9.2) vs. 3.7 months (3.4 – 4.3), p < 0.001].…”

Image_1_The Association of Real-World CA 19-9 Level Monitoring Patterns and Clinical Outcomes Among Patients With Metastatic Pancreatic Ductal Adenocarcinoma.tif by Ben George (64738)

“…Patients with decreasing/stable CA 19-9 during treatment experienced longer survival than patients who experienced an increase in CA 19-9 levels [1L: 10.9 months (10.5 – 11.3) vs. 5.4 months (5.1 – 5.9), p < 0.0001; 2L: 8.2 months (7.7 – 8.5) vs. 4.3 months (4.1 – 4.7), p < 0.001; 3L: 7.5 months (6.6 – 9.2) vs. 3.7 months (3.4 – 4.3), p < 0.001].…”

Image_2_The Association of Real-World CA 19-9 Level Monitoring Patterns and Clinical Outcomes Among Patients With Metastatic Pancreatic Ductal Adenocarcinoma.tif by Ben George (64738)

“…Patients with decreasing/stable CA 19-9 during treatment experienced longer survival than patients who experienced an increase in CA 19-9 levels [1L: 10.9 months (10.5 – 11.3) vs. 5.4 months (5.1 – 5.9), p < 0.0001; 2L: 8.2 months (7.7 – 8.5) vs. 4.3 months (4.1 – 4.7), p < 0.001; 3L: 7.5 months (6.6 – 9.2) vs. 3.7 months (3.4 – 4.3), p < 0.001].…”

Pulmonary Abnormalities in Mice with Paracoccidioidomycosis: A Sequential Study Comparing High Resolution Computed Tomography and Pathologic Findings by Damaris Lopera (246539)

“…The experimental design used decreases the need to sacrifice a large number of animals, and serves to monitor treatment efficacy by means of a more rational approach to the study of human lung disease.…”

Image 1_Relationship between triglyceride glucose-body mass index baselines and variation with future cardiovascular diseases risk in the middle-aged and elderly individuals.jpeg by Junpeng Qiao (11726521)

“…After adjusting for potential confounding factors, compared to participants with consistently low TyG-BMI levels, those with moderate TyG-BMI levels and a slowly increasing trend had an HR of 1.27 (95% CI 1.10-1.47), while those with the highest TyG-BMI levels and a slowly decreasing trend had an HR of 1.52 (95% CI 1.26-1.83).…”

Image 2_Relationship between triglyceride glucose-body mass index baselines and variation with future cardiovascular diseases risk in the middle-aged and elderly individuals.jpeg by Junpeng Qiao (11726521)

“…After adjusting for potential confounding factors, compared to participants with consistently low TyG-BMI levels, those with moderate TyG-BMI levels and a slowly increasing trend had an HR of 1.27 (95% CI 1.10-1.47), while those with the highest TyG-BMI levels and a slowly decreasing trend had an HR of 1.52 (95% CI 1.26-1.83).…”

Table 1_Relationship between triglyceride glucose-body mass index baselines and variation with future cardiovascular diseases risk in the middle-aged and elderly individuals.docx by Junpeng Qiao (11726521)

“…After adjusting for potential confounding factors, compared to participants with consistently low TyG-BMI levels, those with moderate TyG-BMI levels and a slowly increasing trend had an HR of 1.27 (95% CI 1.10-1.47), while those with the highest TyG-BMI levels and a slowly decreasing trend had an HR of 1.52 (95% CI 1.26-1.83).…”

Figure 2 from Auranofin Synergizes with Cisplatin in Reducing Tumor Burden of NOTCH-Dependent Ovarian Cancer by Robert J. Lake (22408833)

“…ED25, ED50, ED75, and ED100 = 25%, 50%, 75%, and 100% inhibition of viability, respectively. …”

Other calpain inhibitors in RGC damage in hypoxic retina. by Emi Nakajima (21703141)

“…<p>(A) The IC50 of calpain inhibitors against calpains 1 and 2 in vitro.…”

Social interaction involves CeA neurons. by Karolina Rojek-Sito (13197192)

“…All the data are shown as the mean ± SEM, and dots represent individual data points, * <i>p</i> < 0.05, ** <i>p</i> < 0.01, *** <i>p</i> < 0.001. …”

<i>pals-17</i> mutant phenotypes are fully <i>pals-16</i>-dependent. by Vladimir Lažetić (5047592)

“…<p>(A, B) <i>pals-16</i> RNAi decreases <i>pals-5</i>p::GFP expression in <i>pals-17 pals-20</i> mutants. …”

CNNM4 but not SLC41A1 stimulates TRPM7-mediated divalent cation entry. by Zhiyong Bai (259036)

“…The fluorescence intensity of the cells (mean of 50 cells) were quantified for each time point. …”

Effects of the Pgp inhibitor tariquidar (TQ; 0.5 µM) in three functional assays, in which alterations in Pgp efflux are indirectly measured by determining intracellular concentrati... by Andreas Noack (519906)

“…In the absence of doxycycline (open columns), tariquidar significantly increased Rho123 accumulation (i.e., decreased Rho123 efflux) by only about 15%. In the presence of doxycycline, accumulation of Rho123 was only about 50% of that under doxycycline-off conditions, which was completely counteracted by tariquidar. …”

Image_2_Healthcare Workers in South Korea Maintain a SARS-CoV-2 Antibody Response Six Months After Receiving a Second Dose of the BNT162b2 mRNA Vaccine.jpeg by Jae Hong Choi (3339120)

“…</p>Results<p>A total of 249 healthcare workers at Jeju National University Hospital were enrolled in this study, and 982 blood samples were analyzed. The mean age was 38.1 ± 9.5 years, and 145 (58.2%) participants were females. …”

Table 1_The impact of comorbidities on surgical outcome and mortality in minimally invasive mitral valve surgery: a systematic review.docx by Vanessa I. T. Zwaans (22163257)

“…Left atrial (LA) diameter decreased significantly from 50.37 mm preoperatively to 40.41%mm postoperatively (p < 0.001), LVDD was significantly reduced after MIMVS (p < 0.001). …”

Table_1_Residential greenness attenuated association of long-term air pollution exposure with elevated blood pressure: Findings from polluted areas in Northern China.docx by Yayuan Mei (12324884)

“…And participants aged ≥50 years were more susceptible to the harmful effect of PM_2.5 and PM₁₀ compared to younger adults.…”

Image_1_Healthcare Workers in South Korea Maintain a SARS-CoV-2 Antibody Response Six Months After Receiving a Second Dose of the BNT162b2 mRNA Vaccine.jpg by Jae Hong Choi (3339120)

“…</p>Results<p>A total of 249 healthcare workers at Jeju National University Hospital were enrolled in this study, and 982 blood samples were analyzed. The mean age was 38.1 ± 9.5 years, and 145 (58.2%) participants were females. …”

Adrenergic Receptor Polymorphism and Maximal Exercise Capacity after Orthotopic Heart Transplantation by Mélanie Métrich (3138819)

“…<div><p>Background</p><p>Maximal exercise capacity after heart transplantion (HTx) is reduced to the 50–70% level of healthy controls when assessed by cardiopulmonary exercise testing (CPET) despite of normal left ventricular function of the donor heart. …”

DataSheet1_Alteration of the Sitting and Standing Movement in Adult Spinal Deformity.DOCX by Eddy Saad (11939807)

“…The range of motion (ROM) and mean values of pelvis, lower limbs, thorax, head, and spinal segments were calculated on the kinematic waveforms. …”

Early initiation of breastfeeding and severe illness in the early newborn period: An observational study in rural Bangladesh by Shahreen Raihana (828393)

“…<div><p>Background</p><p>In Bangladesh, neonatal sepsis is the cause of 24% of neonatal deaths, over 65% of which occur in the early-newborn stage (0–6 days). Only 50% of newborns in Bangladesh initiated breastfeeding within 1 hour of birth. …”