Data Sheet 1_Heterogeneity of ventricular action potentials in neonatal rat cardiomyocytes and methodological aspects of patch clamp measurements.docx by Pascal Syren (20762843)

“…We analyzed the impact on different output parameters, namely, maximal upstroke velocity (dV/dt), maximal AP amplitude (APA) and AP duration at different percentages (XX%) of repolarization, APD_XX. In a comparative literature research, we found that mean APD₉₀ in between 27.0 and 560.7 ms (own data 59.7 ± 5.8 ms) were described, with high variability and likely non-Gaussian distribution. …”

Data_Sheet_1_Sleep-Disordered Breathing Is Associated With Reduced Left Atrial Strain Measured by Cardiac Magnetic Resonance Imaging in Patients After Acute Myocardial Infarction.d... by Michael Wester (7359473)

“…Patients with improved SDB (ΔAHI < −5/h) exhibited a mean improvement of LA reservoir strain of +7.2 ± 8.4% whereas patients with SDB deterioration (ΔAHI> + 5/h) showed a mean decrease of −5.3 ± 11.0% (p = 0.0131). …”

Table_1_Radium Mass Balance Sensitivity Analysis for Submarine Groundwater Discharge Estimation in Semi-Enclosed Basins: The Case Study of Long Island Sound.XLSX by Joseph Tamborski (7379624)

“…Short-lived Ra isotope mass balances are sensitive to internal Ra fluxes, including desorption from resuspended particles and inputs from sediment diffusion and bioturbation. A 50% increase in the sediment diffusive flux of ²²⁴Ra, ²²⁶Ra, and ²²⁸Ra results in a ∼30% decrease in the ²²⁴Ra SGD flux, but only a ∼6–10% decrease in the ²²⁶Ra and ²²⁸Ra SGD flux. …”

Image 1_Population pharmacokinetics of polymyxin B in critically ill patients with carbapenem-resistant organisms infections: insights from steady-state trough and peak plasma conc... by Jun Yang (2084)

“…Bland-Altman analysis revealed a mean bias of 12.98 mg·h·L^-1 between the two AUC_ss,24h estimation methods. …”

DSS-induced colitis mouse model. by William C. Reisdorf (6616148)

“…Experimental groups were: Sham = vehicle control (no DSS or other treatment, n = 6), DSS = DSS-only (n = 12), CsA = 10 mg/kg i.p. treatment (n = 6), EPHX2i = GSK1910364A 50 mg/kg orally, twice daily (n = 6). (<b>A</b>) Mean DAI is plotted versus time; error bars reflect standard errors. …”

Image_1_Deep brain stimulation in Early Onset Parkinson's disease.JPEG by Patricia Krause (9398407)

“…These improvements were accompanied by a significant 59% LEDD reduction (p < 0.001), a significant 6.6 ± 16.1 points reduction of impulsivity (p = 0.02; n = 35) and a significant 30 ± 50% improvement of QoL (p = 0.01). …”

SWR-associated increase in neuronal firing rates is weakened in APP/PS1 mice in both dCA1 and vCA1. by Udaysankar Chockanathan (18510288)

“…(M) In vCA1, the SWR log₁₀(modulation index) was significantly decreased in APP/PS1 mice relative to C57BL/6 controls (mean ± std: C57BL/6 = 3.50 ± 1.49, APP/PS1 = 2.28 ± 1.70 Hz, p < 10⁻⁶, two-sided Wilcoxon rank-sum test, n_C57BL/6 = 689 neurons, n_APP/PS1 = 651 neurons).…”

Shifts caused by control and Grin2c siRNAs in stimulation threshold and maximum response rate. by Giovanni Hernandez (236411)

“…<p><b>A-B)</b> Histogram bars represent means +/- SEM; saline injection in the VTA does not produces a reliable change in M50 nor MAX <b>C)</b> Treatment with the control siRNA did not produce a significant change in the stimulation threshold (M50), but the treatment with the siRNA against the Grin2c subunit produces a significant increase. …”

Reduced VEGF disrupts the parenchyma around airways and vasculature. by Minna M. Wieck (849372)

“…<i>White and black arrows</i> point to magnified areas shown in insets. Scale bars represent 50 μm. Data are expressed as mean ± SD, *P< 0.05, **P< 0.01 versus control.…”

The effect of stretch on the MAP of the fish heart. by Simon M. Patrick (364948)

“…MAPD is shown at MAPD25 (A,D), MAPD50 (B,E) and MAPD90 (C,F) (mean ± S.E.M, <i>p</i><0.05). …”

Independent model predictions versus experimental observations. by Ryan Tasseff (253998)

“…The ensemble predicted an approximate 50% decrease in androgen stimulated PSA expression due to AR knock-down 72 hours after treatment. …”

SINGLE PORT LAPAROSCOPIC CHOLECYSTECTOMY: TECHNICAL ASPECTS AND RESULTS by Murillo de Lima FAVARO (5670416)

“…Conversion to open surgery occurred in three cases (1.76%). The mean surgical time was 67.97 min, showing a marked decrease when was reached close to 50 cases and a stabilization after 100 surgeries. …”

CA and HT abolished the <i>in vivo</i> obesogenic effect of RGZ. by Esmail Lutfi (848005)

“…Exposure to 1 μM RGZ induced a significantly smaller decrease in adiposity compared with CT. The effect of RGZ was abolished by CA 50 μM (A) and HT (100 μM) (B). …”

BMC Neuroscience-5 by Javier A Bravo (19963)

“…Upper microphotograph shows a 40× magnification (scale bar = 50 μm). The middle microphotographs show details of the same field at 100× magnification (scale bar = 20 μm). …”

Perifosine targets the Aldefluor-positive cell population in breast cancer xenografts. by Hasan Korkaya (159560)

“…<p>(A–C). 50,000 cells from SUM159 cell line or two breast cancer xenografts, MCI, or UM2 were injected into NOD/SCID mice and the tumor size was monitored. …”

Effect of signaling pathway inhibitors on ox-LDL-induced Klotho downregulation in proximal tubular cells. by Cristina Sastre (503532)

“…<p>Pretreatment of MCT with parthenolide (1 µM) or PD098059 (50 µM) for 1 hour attenuates the decrease in Klotho mRNA (<b>A</b>) and protein (<b>B</b>) induced by ox-LDL (25 µg/mL). …”

Different simulation protocols of increased firing and depressed activity. by Isabelle Ayumi Spühler (444465)

“…During this initial period the uptake and release of dopamine reach a steady state level of local dopamine concentration. After 4 sec, 50% of release sites increase or decrease their release for a short time window to simulate phasic firing of the dopaminergic neurons. …”

DRE reduces the viability of MV-4-11 cells in a time dependent manner. by Pamela Ovadje (332426)

“…The absorbance readings were analyzed using GraphPad Prism version5.0 and values are expressed as mean ± SD from quadruplicates of 3 independent experiments. …”

Sensitivity of biomass and cumulative harvest to magnitude of climate impacts under alternative management strategies. by Jameal F. Samhouri (10136090)

“…<p>Outcomes of implementing fixed versus annual climate adaptive harvest management strategies on mean population biomass and cumulative harvest over 50-year simulations in a population subject to a gradual decrease or increase in carrying capacity <b>(a, d)</b>, productivity <b>(b, e)</b>, and both carrying capacity and productivity <b>(c, f)</b>. …”

SOCS-1 silencing enhances cytokine production and stimulatory capacity of mo-DCs. by Meenakshi Sachdeva (817136)

“…(a) Mo-DCs treated with siSOCS-1 had around 50% decrease in the expression of SOCS-1 gene which was significantly less than the control cells (p<0.05). …”