Incentive motivation in first-episode psychosis: A behavioural study-1 by Graham K Murray (48553)

H3 K36 Methylation Helps Determine the Timing of Cdc45 Association with Replication Origins by Fiona Pryde (263331)

Table1_Older postmenopausal women with lower lean mass have hypermethylated sites in the PI3K-Akt pathway.xlsx by Igor Massari Correia (15201868)

“…</p><p>Methods: A cross-sectional study comprised 40 women aged 50–70 years. After K-means cluster analysis the 40 participants were divided into two groups, the Lower Lean Mass group with 20 participants (61.1 ± 4.6 years) and the Higher Lean Mass group with 20 participants (60.7 ± 3.2 years). …”

Table1_Older postmenopausal women with lower lean mass have hypermethylated sites in the PI3K-Akt pathway.xlsx by Igor Massari Correia (15201868)

“…</p><p>Methods: A cross-sectional study comprised 40 women aged 50–70 years. After K-means cluster analysis the 40 participants were divided into two groups, the Lower Lean Mass group with 20 participants (61.1 ± 4.6 years) and the Higher Lean Mass group with 20 participants (60.7 ± 3.2 years). …”

Trial time course. by Alexander Prehn-Kristensen (262650)

Cancer cell specific effect of the SB-based gene delivery system with the hTERT promoter on cell viability. by In-Sun Hong (284033)

“…<p>Cell viability was assessed using the MTT with or without transfection of the SB system (pT.hTp.HSV-tk.Con with active helper plasmid) following administration of 10, 30, or 50 µg/mL GCV at 3 day post-transfection. GCV alone had negligible effect on effect on the cell viability (A), whereas transfection of the SB system (pT.hTp.HSV-tk.Con with active helper plasmid) following administration of GCV significantly decreased the cancer cell viability in a dose-dependent manner (B). …”

Simultaneous Multi-Species Tracking in Live Cells with Quantum Dot Conjugates by Mathias P. Clausen (492769)

“…In this study, we have taken advantage of this flexibility to demonstrate that it is possible to perform a simultaneous investigation of the lateral dynamics in the plasma membrane of i) the transmembrane epidermal growth factor receptor, ii) the glucosylphospatidylinositol-anchored protein CD59, and iii) ganglioside G_M1-cholera toxin subunit B clusters in a single cell. …”

Data_Sheet_1_The influence of precipitation timing and amount on soil microbial community in a temperate desert ecosystem.pdf by Yao Xiao (227567)

“…The study included five precipitation pattern treatments: a control group (C), as well as groups receiving 50 and 100% of the local mean annual precipitation amount (145 mm) during either the early growing season (E50 and E100) or the late growing season (L50 and L100). …”

Transgenic expression of lamin A in <i>Lmna</i>^−/− cardiomyocytes partially restores ERK1/2 activation and gap junction protein localization. by Richard L. Frock (143372)

“…Asterisks mark intercalated discs with qualitative decreases in Cx43 relative to pan-cadherin staining. …”

Structure and properties of EC5. by Shilpakala Sainath Rao (284155)

<i>par2b</i> is partially required downstream of <i>ap1b1a</i> for aggregate formation and increased <i>mmp9</i> expression in the epidermis. by Julia Hatzold (44687)

“…Compared to the strong <i>mmp9</i> expression observed in 100% of the <i>atp1b1a</i> single mutant embryos, 30% of <i>atp1b1a</i> mutants heterozygous for <i>par2b</i> showed a decreased <i>mmp9</i> expression. Of the <i>atp1b1a-/-; par2b-/-</i> double mutants, 50% did not show obvious <i>mmp9</i> staining, comparable to wild type controls (compare with <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010873#pgen.1010873.g002" target="_blank">Fig 2M</a>), and the other 50% showed weak <i>mmp9</i> staining intensity comparable to that shown in panel (G). …”

Characterization of gemcitabine-resistant subclones. by Fredrik I. Thege (12646919)

“…BxGR-360C cells display remodeled actin cytoskeleton, including increased lamellipodia formation (top inset), and decreased E-cadherin localization to cell-cell junctions (bottom inset), scale bar 50 μm. i) Image analysis of E-cadherin enrichment at cell-cell junctions in BxGR-360C cells relative to BxPC3 cells. …”

RSK and PDK1 contribute to Ca²⁺-induced force, MYPT1 and RLC₂₀ phosphorylation in α-toxin permeabilized rabbit pulmonary artery SM. by Mykhaylo Artamonov (389145)

“…(C) BI-D1870 (100 nM) was without effect on the ATP-induced rate of force development in Triton permeabilized mouse ileum SM with pre-thiophosphorylated light chains and depleted of ATP. T1/2 = 4.8±1.2 sec vs 5.0±1.3 sec in the Control (DMSO) vs BI-D1870 respectively, p = ns, n = 3. …”

Supplemental Figure 3 by Abby Beatty (8876807)

Dorsal and chinmo mutually influence each other’s expression, driving tumor growth while inhibiting differentiation. by Caroline Dillard (15381444)

“…Statistical significance was determined with an Unpaired <i>t</i> test with Welch’s correction. Scale bar = 50 µm. (B) Representative confocal images and quantifications of clone dorsal levels (mean gray value) of GFP-labeled <i>Ras</i>^<i>V12</i><i>; scrib</i>^<i>IR</i> tumors (<i>n</i> = 34, <i>m</i> = 36,09, SD = ± 4,009) and chinmo^OE <i>Ras</i>^<i>V12</i><i>; scrib</i>^<i>IR</i> tumors at Day 6 (<i>n</i> = 45, <i>m</i> = 53,93, SD = ± 7,683). …”

Estimation accuracy in the psychological sciences - Fig 4 by Clintin P. Davis-Stober (2881802)

“…Minimum sample size (per condition) for a power of 50% at the 5% level. The needed sample size per condition decreases with the number of conditions. …”

Table1_Effectiveness of dapagliflozin as an insulin adjunct in type 1 diabetes: a semi-mechanistic exposure-response model.DOC by Victor Sokolov (14181554)

“…Even so, this association remained flat, with a 50% decrease in the basal insulin dose from pretreatment level, resulting in ∼5% increase in glucose exposure. …”

Image_1_Defective Autophagy in T Cells Impairs the Development of Diet-Induced Hepatic Steatosis and Atherosclerosis.TIF by Jacob Amersfoort (6075341)

“…Atg7 deficiency furthermore reduced the hepatic NKT cell population which was decreased to < 0.1% of the lymphocyte population. Interestingly, T cell-specific knock-out of Atg7 decreased the mean atherosclerotic lesion size in the tri-valve area by over 50%. …”

Supplementary Material for: Dermatological and Epidemiological Profiles of Patients with Albinism in São Paulo, Brazil, between 2010 and 2017: A Cross-Sectional Study by Marçon C.R. (7320071)

“…Of the 146 records with information, 38 had skin cancer (26%), with a mean age of 47.4 (<i>p</i> < 0.0001); the youngest patient diagnosed with a cutaneous tumor was 23 years old. …”

Table_1_Stable carbon isotopes of dissolved inorganic carbon in the Western North Pacific Ocean: Proxy for water mixing and dynamics.pdf by Tiantian Ge (292883)

“…We found a strong ¹³C Suess Effect in the upper 2,000 m in the western NP Ocean, and δ¹³C-DIC at the surface (<50 m) has decreased by 0.60‰-0.85‰ since 1993. The mean δ¹³C-DIC change in the surface ocean was estimated at 0.28‰ per decade between 1993 and 2019. …”