Detailed prevalence data from gnomAD [24] for ACE2 variants reported in Table 1. by Stuart A. MacGowan (11326845)

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The structure of ACE2 (green) gnomAD [24] missense variant p.Lys26Arg that enhances Spike (light blue) binding affinity. by Stuart A. MacGowan (11326845)

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Structural description of the ACE2 –Spike-protein interface. by Stuart A. MacGowan (11326845)

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mCSM-PPI2 predicted ΔΔG with and without recalibration are in agreement with published deep mutagenesis binding data [22] at low predicted ΔΔG but recalibrated predictions are more... by Stuart A. MacGowan (11326845)

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Estimated allele frequencies of potential novel variants in ACE2 with predicted Spike binding phenotypes. by Stuart A. MacGowan (11326845)

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mCSM-PPI2 predictions for all gnomAD ACE2 missense variants in residues resolved in PDB 6vw1. by Stuart A. MacGowan (11326845)

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Distribution of mCSM-PPI2 [13] predicted ΔΔG from in silico saturation mutagenesis of the ACE2-S interface in PDB 6vw1 [11]. by Stuart A. MacGowan (11326845)

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Surface plasmon resonance derived ΔΔG and mCSM-PPI2 [13] predictions for ACE2 mutants, including gnomAD [24] missense variants, at or near the ACE2 Spike interface. by Stuart A. MacGowan (11326845)

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The relationship between experimental and predicted ΔΔG of ACE2 mutants and relative SARS-CoV-2 pseudotype infectivity reported by Shukla et al [38]. by Stuart A. MacGowan (11326845)

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The structure of ACE2 (green) gnomAD [24] missense variant p.Ser19Pro that enhances Spike (light blue) binding affinity. by Stuart A. MacGowan (11326845)

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Binding affinity determination of ACE2 variants with SARS-CoV-2 Spike. by Stuart A. MacGowan (11326845)

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Covid Host Genetics Initiative [31] Release 3 (accessed: 12^th October 2020) summaries for p.Lys26Arg (rs4646116). by Stuart A. MacGowan (11326845)

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Laminar flow increases the expression of anti-oxidant genes and decreases the inflammatory basal state of GEnC. by Daan C. ‘t Hart (10751645)

Acute GM exposure decreased NADH Fl in basal turn OHCs bathed in T1 imaging buffer. by Heather C. Jensen-Smith (319902)

miR-96 significantly decreases FOXO1 mRNA and protein levels in PCa cells. by Benedikta S. Haflidadóttir (245718)

<i>Vps34</i> KO MEFs show a decrease in LC3 conjugation and LC3 puncta formation upon starvation. by Kelly Devereaux (466106)

Treatment of BME in HNSCC cells decreases c-Met protein expression and its downstream signaling pathways. by Ananthi Rajamoorthi (473300)

Combined therapeutic treatment with 2ME2 and SD-208 additively decreases bone metastases in mice. by Lauren K. Dunn (260121)

GroEL1 decreases integrin and E-selectin expression and induces adhesion molecule production in EPCs. by Yi-Wen Lin (143406)

Downregulation of βig-h3 decreases adhesion, invasion and migration of human osteosarcoma cells in vitro. by Yun-Shan Guo (530568)