Table_3_Inhibition of Rho Kinase by Fasudil Ameliorates Cognition Impairment in APP/PS1 Transgenic Mice via Modulation of Gut Microbiota and Metabolites.XLSX by Yuqing Yan (649254)

“…The metagenomic analysis revealed the abundance of the dominant phyla in all the three groups, including Bacteroidetes (23.7–44%) and Firmicutes (6.4–26.6%), and the increased relative abundance ratio of Firmicutes/Bacteroidetes in ADNS (59.1%) compared to WT (31.7%). In contrast, the Firmicutes/Bacteroidetes ratio was decreased to the WT level in ADF (32.8%). …”

Table_6_Inhibition of Rho Kinase by Fasudil Ameliorates Cognition Impairment in APP/PS1 Transgenic Mice via Modulation of Gut Microbiota and Metabolites.XLSX by Yuqing Yan (649254)

“…The metagenomic analysis revealed the abundance of the dominant phyla in all the three groups, including Bacteroidetes (23.7–44%) and Firmicutes (6.4–26.6%), and the increased relative abundance ratio of Firmicutes/Bacteroidetes in ADNS (59.1%) compared to WT (31.7%). In contrast, the Firmicutes/Bacteroidetes ratio was decreased to the WT level in ADF (32.8%). …”

Table_4_Inhibition of Rho Kinase by Fasudil Ameliorates Cognition Impairment in APP/PS1 Transgenic Mice via Modulation of Gut Microbiota and Metabolites.XLSX by Yuqing Yan (649254)

“…The metagenomic analysis revealed the abundance of the dominant phyla in all the three groups, including Bacteroidetes (23.7–44%) and Firmicutes (6.4–26.6%), and the increased relative abundance ratio of Firmicutes/Bacteroidetes in ADNS (59.1%) compared to WT (31.7%). In contrast, the Firmicutes/Bacteroidetes ratio was decreased to the WT level in ADF (32.8%). …”

Table_2_Inhibition of Rho Kinase by Fasudil Ameliorates Cognition Impairment in APP/PS1 Transgenic Mice via Modulation of Gut Microbiota and Metabolites.XLSX by Yuqing Yan (649254)

“…The metagenomic analysis revealed the abundance of the dominant phyla in all the three groups, including Bacteroidetes (23.7–44%) and Firmicutes (6.4–26.6%), and the increased relative abundance ratio of Firmicutes/Bacteroidetes in ADNS (59.1%) compared to WT (31.7%). In contrast, the Firmicutes/Bacteroidetes ratio was decreased to the WT level in ADF (32.8%). …”

Table_5_Inhibition of Rho Kinase by Fasudil Ameliorates Cognition Impairment in APP/PS1 Transgenic Mice via Modulation of Gut Microbiota and Metabolites.XLSX by Yuqing Yan (649254)

“…The metagenomic analysis revealed the abundance of the dominant phyla in all the three groups, including Bacteroidetes (23.7–44%) and Firmicutes (6.4–26.6%), and the increased relative abundance ratio of Firmicutes/Bacteroidetes in ADNS (59.1%) compared to WT (31.7%). In contrast, the Firmicutes/Bacteroidetes ratio was decreased to the WT level in ADF (32.8%). …”

Image_1_Inhibition of Rho Kinase by Fasudil Ameliorates Cognition Impairment in APP/PS1 Transgenic Mice via Modulation of Gut Microbiota and Metabolites.tif by Yuqing Yan (649254)

“…The metagenomic analysis revealed the abundance of the dominant phyla in all the three groups, including Bacteroidetes (23.7–44%) and Firmicutes (6.4–26.6%), and the increased relative abundance ratio of Firmicutes/Bacteroidetes in ADNS (59.1%) compared to WT (31.7%). In contrast, the Firmicutes/Bacteroidetes ratio was decreased to the WT level in ADF (32.8%). …”

Table_1_Inhibition of Rho Kinase by Fasudil Ameliorates Cognition Impairment in APP/PS1 Transgenic Mice via Modulation of Gut Microbiota and Metabolites.XLSX by Yuqing Yan (649254)

“…The metagenomic analysis revealed the abundance of the dominant phyla in all the three groups, including Bacteroidetes (23.7–44%) and Firmicutes (6.4–26.6%), and the increased relative abundance ratio of Firmicutes/Bacteroidetes in ADNS (59.1%) compared to WT (31.7%). In contrast, the Firmicutes/Bacteroidetes ratio was decreased to the WT level in ADF (32.8%). …”

Gender-Specific Effects of Genetic Variants within Th1 and Th17 Cell-Mediated Immune Response Genes on the Risk of Developing Rheumatoid Arthritis by Rafael Cáliz (452151)

“…In men, carriers of the <i>DC-SIGN</i>_rs2287886A allele had an increased risk of RA (OR = 1.70, 95%CI 1.03–2.78), whereas carriers of the <i>DC-SIGN</i>_rs4804803G had a decreased risk of developing the disease (OR = 0.53, 95%CI 0.32–0.89). …”

Data_Sheet_1_Secular trends in the prevalence of meeting 24-hour movement guidelines among U.S. adolescents: evidence from NHANES 2007–2016.docx by Xue-qing Liu (18293836)

“…Compliance with PA and SB recommendations among adolescents has decreased over time, from 72.5% (65.9% to 79.2%) to 64.2% (57.4% to 70.9%) for PA, and from 59.0% (49.6% to 68.4%) to 46.6% (37.8% to 55.5%) for SB, respectively, from 2007–2008 cycle to 2015–2016 cycle. …”

Data_Sheet_1_Prognostic Impact of Left Ventricular Ejection Fraction in Patients With Moderate Aortic Regurgitation: Potential Implications for Treatment Decision-Making.pdf by Qinghao Zhao (11182500)

“…</p>Methods:<p>In total, 1,211 consecutive patients with moderate AR (jet width, 25–64% of LV outflow tract; vena contracta, 0.3–0.6 cm; regurgitant volume, 30–59 mL/beat; regurgitant fraction, 30–49%; effective regurgitation orifice, 0.10–0.29 cm²) prospectively registered between April and June 2018 at 46 academic hospitals were included. …”

Image 1_Enhancing yield and quality: research and practice of agro-forest waste for Lentinus edodes (shiitake mushroom) cultivation.jpg by Hongyan Xu (29047)

“…</p>Results<p>Results showed that the average duration to complete stages 2 and 3 of mycelial growth on 10% KP substrates significantly decreased compared to the OS group by 11.0 and 10.7 days, respectively. …”

Interferon-free therapy with direct acting antivirals for HCV/HIV-1 co-infected Japanese patients with inherited bleeding disorders by Haruka Uemura (4521400)

“…</p><p>Results</p><p>Eighteen (67%) patients had had received interferon-based therapy, and 11 (41%) had compensated cirrhosis. HCV genotypes were GT1a 4 (15%), GT1b 16 (59%), GT1 undetermined 2 (7%), GT2a 1 (4%), GT3a 3 (11%) and GT4a 1 (4%). …”

Data_Sheet_1_Trajectories of (Bio)markers During the Development of Cognitive Frailty in the Doetinchem Cohort Study.pdf by M. Liset Rietman (6760496)

“…</p><p>Methods: The Doetinchem Cohort Study is a longitudinal population-based study that started in 1987–1991 in men and women aged 20–59 years, with follow-up examinations every 5 years. …”

Data_Sheet_2_Trajectories of (Bio)markers During the Development of Cognitive Frailty in the Doetinchem Cohort Study.pdf by M. Liset Rietman (6760496)

“…</p><p>Methods: The Doetinchem Cohort Study is a longitudinal population-based study that started in 1987–1991 in men and women aged 20–59 years, with follow-up examinations every 5 years. …”

Data_Sheet_1_The Effect of Sex and Wealth on Population Attributable Risk Factors for Dementia in South Africa.docx by Kirsten Bobrow (5733674)

“…Together, 45% of dementia cases may be attributable to modifiable risk factors (95% CI 25–59%). We found significant interactions (p < 0.005) between sex, wealth, or both (sex ^* wealth) and each risk factor except social isolation and physical activity. …”

Data Sheet 1_Resistance characteristics of culture-positive tuberculosis from 2015 to 2022.xlsx by Zhenzhen Wang (250368)

“…During the study period, the proportion of mono-resistance tuberculosis (MR-TB), multidrug-resistant tuberculosis (MDR-TB) and polydrug-resistant tuberculosis (PDR-TB) decreased by 59.2% (12.9–5.3%), 40.3% (12.4–7.4%), and 68.3% (6.9–2.2%), respectively. …”

Transfusion: -80°C Frozen Blood Products Are Safe and Effective in Military Casualty Care by Femke Noorman (3396926)

“…In hospital mortality decreased post-MTP for MT patients from 44% to 14% (P = 0.005) and for non-MT patients from 12.7% to 5.9% (P = 0.139). …”

DataSheet_1_Use of gliptins reduces levels of SDF-1/CXCL12 in bullous pemphigoid and type 2 diabetes, but does not increase autoantibodies against BP180 in diabetic patients.docx by Antti Nätynki (332450)

“…Using an ELISA assay, we showed that IgG autoantibodies against the immunodominant NC16A domain of BP180 were found in 5.9% of gliptin treated and in 6.6% of non-gliptin treated T2D patients. …”

DataSheet_1_Constraining the origin of sedimentary organic matter in the eastern Guangdong coast of China using δ13C and δ15N.docx by Junwen Wu (1832728)

“…Overall, this study establishes a background carbon database in the coastal environment that can be used in future studies of blue carbon to achieve carbon neutrality in China.…”

Table_2_Screening and Validation of p38 MAPK Involved in Ovarian Development of Brachymystax lenok.XLSX by Tianqing Huang (631219)

“…<p>Brachymystax lenok (lenok) is a rare cold-water fish native to China that is of high meat quality. …”