EWS/FLI-1 and R1507 influence the activation/expression of key molecules in the IGF-1 signaling pathway. by Helen J. Huang (201553)

“…TC-71 cells were transfected with reagent alone, 50 nM non-targeted (NT) siRNA, or 50 nM EWS/FLI-1 siRNA for 48 hours. …”

Modelling and thermodynamic properties of the drying of strawberries by Gabriel Henrique Horta de OLIVEIRA (10424342)

“…The Logarithmic model was the one that best fitted the drying phenomenon of strawberry fruits, presenting values for the mean relative error between 7.59 and 8.48%, with an estimated standard error between 0.03 and 0.06 and determination coefficient between 99.93 and 99.95%. …”

Image_1_Metyrapone Versus Osilodrostat in the Short-Term Therapy of Endogenous Cushing’s Syndrome: Results From a Single Center Cohort Study.jpg by Mario Detomas (11304897)

“…This tendency persisted at T2 (-37.3% vs -50.1%; median drug dose: 1250 mg vs 6 mg) while at T3 a decrease in UFC from T0 was more pronounced in the metyrapone group (-71.5% vs -51.5%; median dose 1250 mg vs 7 mg). …”

Impact of mepolizumab in patients with high-burden severe asthma within a managed care population by Njira L. Lugogo (13119569)

“…Of the 264 patients with ≥1 OCS claim during baseline, 191 (72.3%) showed a decrease in mean daily OCS use by ≥50% in 117 patients (61.3%). …”

Table_1_Metyrapone Versus Osilodrostat in the Short-Term Therapy of Endogenous Cushing’s Syndrome: Results From a Single Center Cohort Study.docx by Mario Detomas (11304897)

“…This tendency persisted at T2 (-37.3% vs -50.1%; median drug dose: 1250 mg vs 6 mg) while at T3 a decrease in UFC from T0 was more pronounced in the metyrapone group (-71.5% vs -51.5%; median dose 1250 mg vs 7 mg). …”

M002 infection and cell survival. by Michael L. Megison (469463)

“…After 72 hr of treatment, cell viability was measured with alamarBlue™ assays. Data reported as mean ± standard error of the mean. There was a significant decrease in viability in all cell lines following M002 treatment. …”

Telomere shortening culminates in tissue defects associated with aging. by Madalena C. Carneiro (102302)

“…Data are represented as mean +/- SEM.</p>…”

Data Sheet 1_Emotional prompting amplifies disinformation generation in AI large language models.docx by Rasita Vinay (21006911)

“…Impolite prompting resulted in a significant decrease in disinformation production across all models (davinci-002, 59%; davinci-003, 44%; and gpt-3.5-turbo, 28%) and a slight reduction for gpt-4 (94%).…”

Image1_Berberine Improves Irinotecan-Induced Intestinal Mucositis Without Impairing the Anti-colorectal Cancer Efficacy of Irinotecan by Inhibiting Bacterial β-glucuronidase.TIF by Bei Yue (8638605)

“…LC-MS analysis showed that berberine decreased the content of SN38 in feces, which correlated with decreases in both GUS activity and GUS-producing bacteria. …”

DataSheet1_Berberine Improves Irinotecan-Induced Intestinal Mucositis Without Impairing the Anti-colorectal Cancer Efficacy of Irinotecan by Inhibiting Bacterial β-glucuronidase.do... by Bei Yue (8638605)

“…LC-MS analysis showed that berberine decreased the content of SN38 in feces, which correlated with decreases in both GUS activity and GUS-producing bacteria. …”

Image2_Berberine Improves Irinotecan-Induced Intestinal Mucositis Without Impairing the Anti-colorectal Cancer Efficacy of Irinotecan by Inhibiting Bacterial β-glucuronidase.TIF by Bei Yue (8638605)

“…LC-MS analysis showed that berberine decreased the content of SN38 in feces, which correlated with decreases in both GUS activity and GUS-producing bacteria. …”

DataSheet_1_Evolutions of upwelling and terrestrial organic matter input in the inner shelf of the East China Sea in the last millennium revealed by long-chain alkyl diols proxies.... by Chuanhui Song (9986569)

Data_Sheet_1_Association between healthy eating index-2015 and abdominal aortic calcification among US Adults.docx by Jundi Jia (12864167)

“…After adjusting for covariates, higher HEI-2015 was associated with decreased AAC score (AAC-24: β = −0.121, 95% CI: −0.214, −0.028, P = 0.010; AAC-8: β= −0.054, 95% CI: −0.088, −0.019, P = 0.003) and lower risk of AAC (OR = 0.921, 95% CI: 0.855, 0.993, P = 0.031). …”

Nav1.7 KOs are insensitive to painful thermal, mechanical, and chemical stimuli. by Jacinthe Gingras (625973)

“…(<b>48°C</b>: WT/HET, 42.2 sec ±2.6 sec and KO, 59 sec ±1 sec; <b>50°C</b>: WT/HET 25.2 sec ±1.5 sec and KO, 59 sec ±0.2 sec; <b>52.5°C</b>: WT/HET, 17.7 sec ±1.2 sec and KO, 30 sec ±0 sec; <b>55°C</b>: WT/HET, 6.9 sec ±0.9 sec and KO, 20 sec ±0 sec (mean ± S.E.M., Wilcoxon two-sample exact test, 48°C: p = 4.470 E-08; 50°C: p = 3.806 E-08; 52.5°C: p = 5.956 E-11; 55°C: p = 5.956 E-11). …”

Loop C residues modulate activation through a complex network of interactions. by Ákos Nemecz (356830)

“…<p>Stick representation of the evaluated Arg, Asp, Glu, and Lys residues are labeled and color coded based upon effect, with Asp/Glu pink residues producing a strong decrease in pH₅₀ when mutated in combination, and yellow residues producing a nonsignificant or weak effect. …”

Treatment of gp130^757FF mice with WP1066 reduces tumour size. by Louise M. Judd (185660)

“…Antral tumours in 8 week untreated mice (A) and 10 week DMSO-treated vehicle controls (B) were no different in mean area, however WP1066 treatment resulted in ∼50% smaller tumours (C). …”

Effects of site-specific sustained photostimulation of inhibitory neurons within the pre-Bötzinger complex <i>in situ</i>. by Jessica Ausborn (5147210)

“…(<b>D</b>) Summary data (n = 10, mean ± SEM, **p<0.01, *p<0.05) of bilateral pre-BötC photostimulation shows that relatively weak (0.5–2.0 mW) stimulation significantly increased respiratory frequency in a laser power-dependent manner, and stronger (4.0–5.0 mW) stimulation caused a decrease of inspiratory frequency with complete termination of inspiratory activity for the stimulus duration at the maximum laser power (5.0 mW).…”

Characterization of phenotypically unique accessions. by Maria Stefania Przybylska (22756354)

“…</i></i> common accessions classification. Mean Decrease Accuracy (top) and Mean Decrease Gini (bottom) of the random forest models are presented. …”

Eight-year trajectories of changes in health-related quality of life in knee osteoarthritis: Data from the Osteoarthritis Initiative (OAI) by Soili Törmälehto (692961)

“…Group-based trajectory modeling was used to identify patterns of experiencing a decrease of ≥10 points (Minimal Important Change, MIC) in the Quality of Life subscale of the Knee injury and Osteoarthritis Outcome Score compared to baseline. …”

Decline in SHP2 activity follows decline in ARSB in HepG2 cells and in ARSB-null mice. by Sumit Bhattacharyya (14205)

“…<p><b>(A)</b> The SHP2 activity declined ~36% from (2.49 ± 0.15 nmol/mg protein/0.5 h to 1.59 nmol/mg protein/0.5h) following ARSB silencing (p<0.001; n = 6), and increased to 3.70 ± 0.16 nmol.mg protein/0.5h when ARSB was overexpressed in the HepG2 cells (p<0.001; n = 3). …”