Molecular mechanisms underlying Tao-Hong-Si-Wu decoction treating hyperpigmentation based on network pharmacology, Mendelian randomization analysis, and experimental verification by Jun Chen (4238)

“…The CCK-8 assay indicated that concentrations between 2.5% and 20% were suitable for PIG1 cells, with a 50% cytotoxicity concentration (CC₅₀) of 32.14%. …”

Supplementary Material for: Finerenone in Patients with Chronic Kidney Disease and Type 2 Diabetes: FIDELIO-DKD subgroup from China by Zhang H. (2945919)

“…The key secondary composite outcome included death from cardiovascular causes, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. Results: After a median follow-up of 30 months, the finerenone group showed a relative risk reduction (RRR) of 41% (hazard ratio [HR]=0.59, 95% confidence interval [CI], 0.39 to 0.88; p=0.009) for the primary composite outcome compared with placebo, consistent across its components with treatment benefits with finerenone. …”

Supplementary Material for: Finerenone in Patients with Chronic Kidney Disease and Type 2 Diabetes: FIDELIO-DKD subgroup from China by Zhang H. (2945919)

“…The key secondary composite outcome included death from cardiovascular causes, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. Results: After a median follow-up of 30 months, the finerenone group showed a relative risk reduction (RRR) of 41% (hazard ratio [HR]=0.59, 95% confidence interval [CI], 0.39 to 0.88; p=0.009) for the primary composite outcome compared with placebo, consistent across its components with treatment benefits with finerenone. …”

Supplementary Material for: Finerenone in Patients with Chronic Kidney Disease and Type 2 Diabetes: FIDELIO-DKD subgroup from China by Zhang H. (2945919)

“…The key secondary composite outcome included death from cardiovascular causes, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. Results: After a median follow-up of 30 months, the finerenone group showed a relative risk reduction (RRR) of 41% (hazard ratio [HR]=0.59, 95% confidence interval [CI], 0.39 to 0.88; p=0.009) for the primary composite outcome compared with placebo, consistent across its components with treatment benefits with finerenone. …”

Supplementary Material for: Finerenone in Patients with Chronic Kidney Disease and Type 2 Diabetes: FIDELIO-DKD subgroup from China by Zhang H. (2945919)

“…The key secondary composite outcome included death from cardiovascular causes, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. Results: After a median follow-up of 30 months, the finerenone group showed a relative risk reduction (RRR) of 41% (hazard ratio [HR]=0.59, 95% confidence interval [CI], 0.39 to 0.88; p=0.009) for the primary composite outcome compared with placebo, consistent across its components with treatment benefits with finerenone. …”

Supplementary Material for: Finerenone in Patients with Chronic Kidney Disease and Type 2 Diabetes: FIDELIO-DKD subgroup from China by Zhang H. (2945919)

“…The key secondary composite outcome included death from cardiovascular causes, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. Results: After a median follow-up of 30 months, the finerenone group showed a relative risk reduction (RRR) of 41% (hazard ratio [HR]=0.59, 95% confidence interval [CI], 0.39 to 0.88; p=0.009) for the primary composite outcome compared with placebo, consistent across its components with treatment benefits with finerenone. …”

Microtubule inhibitors cause cell cycle arrest and induce RKIP expression. by Saad Yousuf (541082)

“…(Data represents the mean ± S.D., of 2 independent experiments performed in triplicate). …”

Data Sheet 1_Effect of levothyroxine on major adverse cardiovascular events in patients with hypothyroidism and cardiovascular disease.docx by Lijia Liu (706103)

“…Compared to those not treated with levothyroxine, patients receiving levothyroxine showed a significantly reduced risk of 3P-MACE (HR, 0.67; 95% CI, 0.55–0.82, p < 0.01), all-cause death (HR, 0.24; 95% CI, 0.16–0.35, p < 0.01), all-cause hospitalization (HR, 0.23; 95% CI, 0.21–0.26, p < 0.01), and cardiovascular-related hospitalization (HR, 0.69; 95% CI, 0.59–0.82, p < 0.01).…”

Species richness of birds along a rainforest elevational gradient in New Britain, Papua New Guinea by Katerina Sam (2561860)

by Subgroup. by David McMillon (546087)

Zinc availability regulates the lifespan of <i>C</i>. <i>elegans</i>. by Jitendra Kumar (144555)

Self-report of psychological symptoms in hypoparathyroidism patients on conventional therapy by Amanda J. Arneiro (5256824)

Effect of frequency on expansion activity. by Jordan Thurgood (123527)

Supplemental Figure 1 by lsimo2@lsuhsc.edu lsimo2@lsuhsc.edu (6704447)

“…There was a main effect of OVX to decrease HOMA-β at study endpoint. …”

Protective Role of Sirtuin3 (SIRT3) in Oxidative Stress Mediated by Hepatitis B Virus X Protein Expression by Ji-Hua Ren (3181890)

Image_1_Cooperation of arbuscular mycorrhizal fungi and bacteria to facilitate the host plant growth dependent on soil pH.PDF by Zengwei Feng (6583163)

“…Results showed that shoot biomass was the highest in the native soil, while both the decrease and increase in the soil pH reduced the biomass. …”

Table_1_Cooperation of arbuscular mycorrhizal fungi and bacteria to facilitate the host plant growth dependent on soil pH.DOCX by Zengwei Feng (6583163)

“…Results showed that shoot biomass was the highest in the native soil, while both the decrease and increase in the soil pH reduced the biomass. …”

Histological grading of liver injury. by Shaza H. Aly (9276353)

“…In addition, it demonstrated a 68% decrease in lipid peroxide levels compared to the group with paracetamol-induced condition. …”

Physostigmine (5 nM) effect on morphological defenses in dependence of <i>Chaoborus</i> and <i>Gasterosteus</i> kairomone (Bonferroni-corrected Mann-Whitney U comparison). by Linda C. Weiss (165793)

The integrative plot of the metabolites and the relevant pathways changing for thyroidectomy-induced hypothyroidism in circulation system. by Si Wu (154794)