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12721
Table_1_Complete and rapid regeneration of fragments from the upside-down jellyfish Cassiopea.docx
Published 2022“…We conducted a laboratory experiment for which we used 18 Cassiopea medusae of three different size classes that were cut into two pieces each, one fragment with oral arms and one without. …”
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12722
Cost-utility analysis of de-escalating biological disease-modifying anti-rheumatic drugs in patients with rheumatoid arthritis
Published 2020“…We compared continuing treatment (standard care) to a tapering approach (i.e., an immediate 50% dose reduction), withdrawal (i.e., an immediate 100% dose reduction) and tapering followed by withdrawal of bDMARDs. …”
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12723
Antigenic evolution of viruses in host populations
Published 2018“…The fitness slope (effective selection coefficient) is proportional to the reproductive number in the absence of immunity <i>R</i><sub>0</sub> and inversely proportional to the cross-immunity distance <i>a</i>, defined as the genetic distance of a virus strain from a previously infecting strain conferring 50% decrease in infection probability. Analysis predicts that the evolution rate increases linearly with the fitness slope and logarithmically with the genomic mutation rate and the host population size. …”
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12724
Galectin-3 Functions as an Alarmin: Pathogenic Role for Sepsis Development in Murine Respiratory Tularemia
Published 2013“…<div><p>Sepsis is a complex immune disorder with a mortality rate of 20–50% and currently has no therapeutic interventions. …”
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12725
Table_1_Complete and rapid regeneration of fragments from the upside-down jellyfish Cassiopea.docx
Published 2022“…We conducted a laboratory experiment for which we used 18 Cassiopea medusae of three different size classes that were cut into two pieces each, one fragment with oral arms and one without. …”
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12726
Management assumptions for the different productivity pathways
Published 2013“…Our results confirm that yield increase could mitigate some agriculture-related emissions growth over the next decades. Closing yield gaps by 50% for crops and 25% for livestock by 2050 would decrease agriculture and land use change emissions by 8% overall, and by 12% per calorie produced. …”
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12727
Table_2_Small molecules to regulate the GH/IGF1 axis by inhibiting the growth hormone receptor synthesis.xlsx
Published 2022“…Especially in cases of tumor growth there is an urgent need to control the GH/IGF1 axis. In this study we screened a 38,480-compound library, and in two consecutive rounds of analogues selection, we identified active lead compounds based on the following criteria: inhibition the GH receptor (GHR) activity and its downstream effectors Jak2 and STAT5, and inhibition of growth of breast and colon cancer cells. …”
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12728
Profile and variability of intraocular pressure after the EX-PRESS device implant
Published 2019“…We resolved all coplications. Conclusion: The efficacy of EX-PRESS in IOP reduction was verified in the study. …”
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12729
Modeling Soil Organic Carbon Change across Australian Wheat Growing Areas, 1960–2010
Published 2013“…Model simulations show a decreasing trend in SOC over the last 50 years, mainly attributable to relatively low organic carbon (C) inputs. …”
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12730
Aflatoxin B<sub>1</sub> Negatively Regulates Wnt/β-Catenin Signaling Pathway through Activating miR-33a
Published 2013“…The level of miR-33a was up-regulated in hepatocellular carcinoma (HCC) cells treated with AFB<sub>1</sub>, while in the same cells causing the decrease in β-catenin expression when treated at their IC<sub>50</sub> values. miR-33a, specifically miR-33a-5p, was demonstrated to down-regulate the expression of β-catenin, affect the β-catenin pathway, and inhibit cell growth. …”
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12731
Effects of Methylphenidate treatment on circadian heart rate in 19 adolescents.
Published 2020“…<p>We prescribed omega-3 fatty acid supplementation and patients complied in 29 of the 74 adolescents with inappropriate sinus tachycardia, as shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0238139#pone.0238139.t004" target="_blank">Table 4</a>, and we found highly significant effects on heart rate both by day and at night. …”
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12732
Table_1_Small molecules to regulate the GH/IGF1 axis by inhibiting the growth hormone receptor synthesis.xlsx
Published 2022“…Especially in cases of tumor growth there is an urgent need to control the GH/IGF1 axis. In this study we screened a 38,480-compound library, and in two consecutive rounds of analogues selection, we identified active lead compounds based on the following criteria: inhibition the GH receptor (GHR) activity and its downstream effectors Jak2 and STAT5, and inhibition of growth of breast and colon cancer cells. …”
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12733
SamOtos_withStrayAssignment.csv from High dispersal rates in hybrids drive expansion of maladaptive hybridization
Published 2022“…Overall, hybrids with greater than 50% rainbow trout ancestry were 5.7 times more likely to disperse than native or hybrid trout with small amounts of rainbow trout ancestry. …”
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12734
MigrationDispersal_Categorical_GLMs_workflow.r from High dispersal rates in hybrids drive expansion of maladaptive hybridization
Published 2022“…Overall, hybrids with greater than 50% rainbow trout ancestry were 5.7 times more likely to disperse than native or hybrid trout with small amounts of rainbow trout ancestry. …”
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12735
MigrationDispersal_pRBT_GLMs_workflow.r from High dispersal rates in hybrids drive expansion of maladaptive hybridization
Published 2022“…Overall, hybrids with greater than 50% rainbow trout ancestry were 5.7 times more likely to disperse than native or hybrid trout with small amounts of rainbow trout ancestry. …”
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12736
ClintOtos_withStrayAssignment.csv from High dispersal rates in hybrids drive expansion of maladaptive hybridization
Published 2022“…Overall, hybrids with greater than 50% rainbow trout ancestry were 5.7 times more likely to disperse than native or hybrid trout with small amounts of rainbow trout ancestry. …”
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12737
Combined_mig_dis_data.csv from High dispersal rates in hybrids drive expansion of maladaptive hybridization
Published 2022“…Overall, hybrids with greater than 50% rainbow trout ancestry were 5.7 times more likely to disperse than native or hybrid trout with small amounts of rainbow trout ancestry. …”
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12738
Supplementary Material for: Assessment of Adjuvant Trastuzumab-Associated Cardiac Toxicity in Korean Patients with Breast Cancer: A Single-Center Analysis
Published 2013“…<b><i>Background</i></b>: We performed this analysis to investigate the clinical presentation of trastuzumab-associated cardiac toxicity in Korean women. …”
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12739
DataSheet_1_Small molecules to regulate the GH/IGF1 axis by inhibiting the growth hormone receptor synthesis.pdf
Published 2022“…Especially in cases of tumor growth there is an urgent need to control the GH/IGF1 axis. In this study we screened a 38,480-compound library, and in two consecutive rounds of analogues selection, we identified active lead compounds based on the following criteria: inhibition the GH receptor (GHR) activity and its downstream effectors Jak2 and STAT5, and inhibition of growth of breast and colon cancer cells. …”
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12740
Spatial distribution of mercury accumulation in the surface soil of Japanese forests
Published 2020“…The median concentrations of Hg in the litter layer and 0–10 cm of mineral soils were 99 (range: 56.7–297) and 145 (range: 22.8–294) μg kg<sup>−1</sup>, respectively, and tended to decrease down to 50 cm. There was a positive relationship between the Hg and total organic carbon concentrations in soil, suggesting that organic carbon strongly binds with Hg in soil. …”