Doxorubicin-Mediated Bone Loss in Breast Cancer Bone Metastases Is Driven by an Interplay between Oxidative Stress and Induction of TGFβ by Tapasi Rana (339809)

“…Administration of doxorubicin to 4T1 tumor-bearing mice produced an eightfold increase in osteolytic lesion areas compared untreated tumor-bearing mice (<i>P</i> = 0.002) and an almost 50% decrease in trabecular bone volume expressed in BV/TV (<i>P</i> = 0.0005), both of which were rescued by anti-TGFβ antibody (1D11). …”

The changes of urinary levels of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). by Yuan-Hong Jiang (398786)

“…<p>The urinary levels of NGF (pg/ml) and BDNF (pg/ml) were compared between baseline and after 6-month treatment of HA (6M) in responders and non-responders based on (A) a visual analogue scale (VAS, for pain) decrease of ≥ 2, (B) global response assessment (GRA) increase of ≥ 2 and (C) functional bladder capacity (FBC) increase of ≥ 50%. …”

Ionosonde spread F and GPS L-band scintillation occurrence during moderate geomagnetic storms near the southern crest of the EIA in Argentina by Gilda González (9246194)

“…</div><div>• For the storm of October 12, strong range spread-F (SSF) is observed during the recovery phase on October 14 at 5:50 – 8:50 LT. Simultaneously, a positive storm effect is present. …”

MVEC-EVs promoted OPC survival, proliferation, and motility in a dose-dependent manner. by Masashi Kurachi (106280)

“…(A) The proportion of pyknotic nuclei decreased at doses ≥ 50 μg/ml. Results are shown as mean ± SE (N = 8 in each condition). …”

Fishery-Induced Changes in the Subtropical Pacific Pelagic Ecosystem Size Structure: Observations and Theory by Jeffrey J. Polovina (404674)

“…<div><p>We analyzed a 16-year (1996–2011) time series of catch and effort data for 23 species with mean weights ranging from 0.8 kg to 224 kg, recorded by observers in the Hawaii-based deep-set longline fishery. …”

S1 File - by Xiang Ji (324865)

“…<i>padi</i>, with LC₅₀ of 3.59 and 13.78 mg L⁻¹ following 24 h exposure. …”

Effect of AZT and LAC treatments on brain oxidative stress in newborn and adult mice. by Anna Rita Zuena (89723)

Influence of DMF and MMF on NO production of LPS stimulated microglia. by Darius Moharregh-Khiabani (212285)

“…<p>After stimulation for 24 h with 10 ng/ml LPS a dose dependent decrease of NO production in cells incubated with DMF (5, 10, 50µM/ml) could be observed. …”

Microstructure and Wear Resistance of ZrC-ZrB2 /Ni Composite Coatings Prepared by Plasma Transferred Arc Cladding by Tian-guo Guan (6675545)

DNMT3L was found within the adult testis and mature sperm. by Natasha M. Zamudio (225855)

“…Results are presented as means ± SEM. <b>*</b> Indicates a statistically significant decrease in relative intensity of DNMT3L with a p≤0.05.…”

Spontaneous replay switches between multiple environments. by Bastian Pietras (14295598)

“…<p>In the (A) mesoscopic and (B) microscopic ring-attractor network storing multiple environments, metastable replay dynamics spontaneously emerge due to finite-size fluctuations when decreasing the population size from <i>N</i> = 500 (orange/red in panels i) to <i>N</i> = 50 (blue/black) per unit. …”

SEA binds DC-SIGN and can block <i>trans</i>-infection of CD4 T-lymphocytes but not <i>cis</i>-infection. by Emily EIM Mouser (7348559)

“…<b>(D)</b> SEA’s effect on <i>trans</i>-infection was determined by pre-incubating Raji DC-SIGN cells with 1μg/ml SEA for 2h and subsequently adding SF162 (TCID₅₀ 5000) or LAI (TCID₅₀ 500). Viral outgrowth in Raji DC-SIGN—CD4⁺ T-lymphocyte co-cultures was monitored through measuring p24 levels in culture supernatant. …”

Data_Sheet_1_Out-of-Hospital Cervical Ripening With a Synthetic Hygroscopic Cervical Dilator May Reduce Hospital Costs and Cesarean Sections in the United States—A Cost-Consequence... by Sita J. Saunders (8060075)

“…The cesarean-section rate was decreased by 3.78 percentage points (23.28% decreased to 19.50%). …”

Image_2_Asymptomatic Bacterial Vaginosis Is Associated With Depletion of Mature Superficial Cells Shed From the Vaginal Epithelium.jpeg by D. Elizabeth O'Hanlon (8552298)

“…We also compared the superficial cell index (SCI), a measure of cervicovaginal epithelial cell maturity, in no BV and aBV smears with relatively low numbers of shed cells (≤50/100X field). …”

Immunogenicity and Safety of the 13-Valent Pneumococcal Conjugate Vaccine <i>versus</i> the 23-Valent Polysaccharide Vaccine in Unvaccinated HIV-Infected Adults: A Pilot, Prospecti... by Francesca Lombardi (756146)

“…Eligible subjects were recruited into two parallel groups: group 1 (n = 50) received two doses of PCV13 eight weeks apart, and group 2 (n = 50) received one dose of PPSV23, as part of their standard of care. …”

DataSheet4_Peripheral proteomic changes after electroconvulsive seizures in a rodent model of non-response to chronic fluoxetine.PDF by Rodolphe H. Lebeau (14031246)

“…A 28-day chronic fluoxetine treatment (Flx, 18 mg/kg/day) reduced corticosterone-induced increase in emotional behavior. A 50% decrease in emotionality score threshold before and after Flx, was used to separate Flx-responding mice (Flx-R, n = 18), or Flx non-responder mice (Flx-NR, n = 7). …”

Table_1_Investigation of the impact of machine operating parameters on beam delivery time and its correlation with treatment plan characteristics for synchrotron-based proton penci... by Xiaoying Liang (552537)

“…The following incremental improvement in parameters of the 2015 system for the 2025 system played an important role in this decreased BDT: beam intensity (8 to 20 MU/s), recapture efficiency (50% to 80%), number of MEE layers per spill (4 to 8), scanning magnet preparation and verification time (1.9 to 0.95 msec), and MEE layer switch time (200 to 100 msec). …”

Screw location map. by Petr Boháč (20685499)

Identification of osmoadaptive strategies in the halophile, heterotrophic ciliate <i>Schmidingerothrix salinarum</i> by Lea Weinisch (4786002)

Table_1_Asymptomatic Bacterial Vaginosis Is Associated With Depletion of Mature Superficial Cells Shed From the Vaginal Epithelium.XLSX by D. Elizabeth O'Hanlon (8552298)

“…We also compared the superficial cell index (SCI), a measure of cervicovaginal epithelial cell maturity, in no BV and aBV smears with relatively low numbers of shed cells (≤50/100X field). …”