Showing 18,081 - 18,100 results of 24,497 for search '(( 59 ((0 decrease) OR (a decrease)) ) OR ( 50 ((we decrease) OR (mean decrease)) ))', query time: 1.00s Refine Results
  1. 18081

    Visible-Light-Controlled Histone Deacetylase Inhibitors for Targeted Cancer Therapy by Laia Josa-Culleré (2736559)

    Published 2023
    “…Light-activatable drugs, whose activity can be precisely controlled with external light, could provide a more localized action of the drugs in the tumor, thus decreasing side effects and increasing efficacy. Herein, we introduce a series of photoswitchable azobenzene histone deacetylase inhibitors (HDACis) whose activity can be controlled by external visible light. …”
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  7. 18087

    The effects of Mycobacterium tuberculosis on T cell responsiveness in granulomas by Jess Millar (620726)

    Published 2019
    “…At the cellular level, increased IFNγ concentrations are most sensitive to T cell levels between 30-40 days, while sensitivity of the binding threshold of MHCII peptide complexes that are required to activate T cells decreases in relation to T cell levels. Increased concentrations of Mtb antigens is most sensitive to granuloma size and infected macrophage, TNF-induced apoptosis rates from 25-50 days.…”
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  9. 18089

    Repair-Mediated Duplication by Capture of Proximal Chromosomal DNA Has Shaped Vertebrate Genome Evolution by John K. Pace II (264178)

    Published 2009
    “…These events are thought to be a source of genomic instability and human diseases, but it is unclear whether they have contributed significantly to genome evolution. Here we developed an innovative computational pipeline that takes advantage of the repetitive structure of genomes to detect repair-mediated duplication events (RDs) that occurred in the germline and created insertions of at least 50 bp of genomic DNA. …”
  10. 18090

    Data_Sheet_1_The Paradoxical Leishmanicidal Effects of Superoxide Dismutase (SOD)-Mimetic Tempol in Leishmania braziliensis Infection in vitro.PDF by Laíse B. Oliveira (6880472)

    Published 2019
    “…Tempol surfaces as an interesting candidate for the chemotherapy of CL with an IC<sub>50</sub> of 0.66 ± 0.08 mM and selectivity index of 151. …”
  11. 18091

    Obesity is associated with increased basal and postprandial β-cell insulin secretion even in the absence of insulin resistance by Ada Admin (8524211)

    Published 2020
    “…We tested the hypothesis that obesity, independent of insulin resistance, is associated with increased insulin secretion. …”
  12. 18092

    Self-Reducing Copper Precursor Inks and Photonic Additive Yield Conductive Patterns under Intense Pulsed Light by Yitzchak S. Rosen (3752509)

    Published 2017
    “…Finally, we show that by adding as little as 0.5 wt % single-wall CNTs to the ink the absorptance was enhanced by about 50% and the threshold energy required to obtain a conductive pattern decreased by ∼25%. …”
  13. 18093

    Supplementary Material for: Polycystic Ovary Syndrome, Endometriosis and Venous Thromboembolism: A population-based study by figshare admin karger (2628495)

    Published 2025
    “…Results: We observed increasing trends, with a relative increase of 140% (from 0.27% to 0.65%) for PCOS, 16% (from 0.43% to 0.50%) for DVT, and 39% (from 0.23% to 0.32%) for PE, whereas we observed a decline by 34% for endometriosis (from 0.85% to 0.56%). …”
  14. 18094

    Depletion of HDAC6 Enhances Cisplatin-Induced DNA Damage and Apoptosis in Non-Small Cell Lung Cancer Cells by Lei Wang (6656)

    Published 2012
    “…Furthermore, we showed that HDAC6 protein levels were positively correlated with cisplatin IC<sub>50</sub> in 15 NSCLC cell lines. …”
  15. 18095

    Expression of Bcl-2, Bax, Survivin, ERK, cytochrome C, Caspase-3 and VEGF in 4T1 cells after 48 h treatment of fucoidan detected by Western blot. by Meilan Xue (310911)

    Published 2013
    “…Fucoidan decreased VEGF expression in 4T1 cells. Lane 1: control cells; lanes 2–4: 4T1 cells treated with 50, 100 and 200 μg/ml fucoidan respectively. …”
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    Image1_Neuroprotective effects of total phenolics from Hemerocallis citrina Baroni leaves through the PI3K/AKT pathway.pdf by Yanjun Jia (10142216)

    Published 2024
    “…PC12 cells were stimulated with 200 μmol/L Corticosterone (Cort) for 24 h, and then treated with 50, 100 and 200 μg/mL of HLTP for 24 h. The cell viability of damaged cells were significantly increased in a dose-dependent manner by 9.50%, 10.42% and 21.25%, respectively (P < 0.01). …”
  19. 18099

    Table1_Neuroprotective effects of total phenolics from Hemerocallis citrina Baroni leaves through the PI3K/AKT pathway.docx by Yanjun Jia (10142216)

    Published 2024
    “…PC12 cells were stimulated with 200 μmol/L Corticosterone (Cort) for 24 h, and then treated with 50, 100 and 200 μg/mL of HLTP for 24 h. The cell viability of damaged cells were significantly increased in a dose-dependent manner by 9.50%, 10.42% and 21.25%, respectively (P < 0.01). …”
  20. 18100

    Table2_Neuroprotective effects of total phenolics from Hemerocallis citrina Baroni leaves through the PI3K/AKT pathway.docx by Yanjun Jia (10142216)

    Published 2024
    “…PC12 cells were stimulated with 200 μmol/L Corticosterone (Cort) for 24 h, and then treated with 50, 100 and 200 μg/mL of HLTP for 24 h. The cell viability of damaged cells were significantly increased in a dose-dependent manner by 9.50%, 10.42% and 21.25%, respectively (P < 0.01). …”