DataSheet1_Sodium Tanshinone IIA Sulfonate as a Potent IDO1/TDO2 Dual Inhibitor Enhances Anti-PD1 Therapy for Colorectal Cancer in Mice.pdf by Rongjie Zhang (5625083)

“…However, only a few dual inhibitors for IDO1 and TDO2 have been reported. Here, we discovered that sodium tanshinone IIA sulfonate (STS), a sulfonate derived from tanshinone IIA (TSN), reduced the enzymatic activities of IDO1 and TDO2 with a half inhibitory concentration (IC₅₀) of less than 10 μM using enzymatic assays for natural product screening. …”

image_1.PDF by Emma J. Foster (5049770)

“…Half of the sample population were females (50.6%) and the majority had an ischemic stroke (89.8%). …”

Comparison of the Dynesys Dynamic Stabilization System and Posterior Lumbar Interbody Fusion for Lumbar Degenerative Disease by Yang Zhang (30734)

“…The range of motion (ROM) of stabilized segments in Dynesys group decreased from 7.1 ± 2.2° to 4.9 ± 2.2° (<i>P</i> < 0.05), while that of in PLIF group decreased from 7.3 ± 2.3° to 0° (<i>P</i> < 0.05). …”

Detoxification effects of long-chain versus a mixture of medium- and long-chain triglyceride-based fat emulsion on propafenone poisoning by Xusheng An (10461207)

“…<div><p>In the present study, we aimed to compare the detoxifying effects of two fat emulsions containing either long-chain triglyceride or a mixture of medium-chain and long-chain triglycerides in the propafenone-poisoned rat model. …”

Presentation 1_Granola consumption with multiple prebiotics in Japanese participants increases Bifidobacterium abundance and improves stress and subjective sleepiness.pptx by Hiroyuki Sasaki (28675)

“…The participants consumed 50 g of prebiotics-containing granola daily for 8 weeks. …”

Table 1_Analysis of risk factors in breast cancer patients with hand-foot syndrome and oral mucositis caused by pegylated liposomal doxorubicin.doc by Xianghua Quan (21404606)

“…Severe cases may necessitate a reduced PLD dose or even delay or interrupt chemotherapy, ultimately leading to decreased medication compliance. Here, we conduct an analysis of the risk factors associated with HFS and OM during the PLD chemotherapy regimen, thus providing early warning indicators for the potential occurrence of these adverse reactions in BC patients.…”

Supplementary Material for: Gonadotropin-Releasing Hormone Agonists During Gonadal Chemotherapy for the Effect on Pregnancy Outcome and Ovarian Function in Premenopausal Patients W... by Yuan Y. (3237453)

“…For secondary endpoints, the GnRHa group improved menstrual recovery rates (RR=1.20; 95% CI: 1.11-1.30), and decreased the rate of amenorrhea 1-2 years after chemotherapy (RR=0.50; 95% CI: 0.40-0.63). …”

Drug Absorption Efficiency in <em>Caenorhbditis elegans</em> Delivered by Different Methods by Shan-Qing Zheng (382120)

“…</p> <p>Methodology/Principal Findings</p><p>We evaluated the drug absorption efficiency in <i>C. elegans</i> using five frequently used methods with resveratrol with low aqueous solubility and water-soluble 5-Fluoro-2′-deoxyuridine (FUDR) as positive compounds. …”

Table 3_Analysis of risk factors in breast cancer patients with hand-foot syndrome and oral mucositis caused by pegylated liposomal doxorubicin.doc by Xianghua Quan (21404606)

“…Severe cases may necessitate a reduced PLD dose or even delay or interrupt chemotherapy, ultimately leading to decreased medication compliance. Here, we conduct an analysis of the risk factors associated with HFS and OM during the PLD chemotherapy regimen, thus providing early warning indicators for the potential occurrence of these adverse reactions in BC patients.…”

Co-Inoculation with Rhizobia and AMF Inhibited Soybean Red Crown Rot: From Field Study to Plant Defense-Related Gene Expression Analysis by Xiang Gao (4077)

“…The root colony forming unit (CFU) decreased over 50% when inoculated by rhizobia and/or AMF at low P. …”

Physical activity and sedentary behavior in relation to mortality among renal cell cancer survivors by Daniela Schmid (701900)

“…<div><p>Background</p><p>The relations of physical activity and sedentary behavior to mortality risk among patients with renal cell cancer have not yet been evaluated.</p><p>Methods</p><p>We conducted a prospective cohort study among 667 renal cell cancer survivors aged 50–71 years of the National Institutes of Health (NIH)-AARP Diet and Health Study with a median follow-up time of 7.1 years. …”

Table_2_Photoreceptor Degeneration in Pro23His Transgenic Rats (Line 3) Involves Autophagic and Necroptotic Mechanisms.docx by Kiana Kakavand (9593654)

“…<p>Photoreceptor death contributes to 50% of irreversible vision loss in the western world. …”

Supplementary Material for: Nintedanib in IPF: Post hoc Analysis of the Italian FIBRONET Observational Study by Harari S. (11300316)

“…The proportion of patients with cough decreased from 50.0% to 21.2% over 12 months. Two patients experienced exacerbations, 2 patients discontinued treatment, and 27 (51.9%) reported AEs. …”

Granola consumption with multiple prebiotics in Japanese participants increases <i>Bifidobacterium</i> abundance and improves stress and subjective sleepiness by Hiroyuki Sasaki (20851130)

“…The participants consumed 50 g of prebiotics-containing granola daily for 8 weeks. …”

Control of p53 oscillations caused by DNA damage. by Kyung H. Kim (188027)

“…Autocorrelation functions of p53 showed damped oscillations and their amplitudes were increased by decreasing the effective degradation rate of p53 by 50%. …”

Presentation_1_Treatment of in vitro-Matured Bovine Oocytes With Tauroursodeoxycholic Acid Modulates the Oxidative Stress Signaling Pathway.pdf by Elisa Mariano Pioltine (10165832)

“…This study aimed to evaluate the effects of three concentrations of tauroursodeoxycholic acid (TUDCA; 50, 200, and 1,000 μM), a chemical chaperone for relieving ER stress, during IVM of bovine cumulus–oocyte complexes (COCs) for 24 h. …”

Data Sheet 1_Menthone lowers H3K27ac levels to inhibit Fusarium proliferatum growth.docx by Li-Yan Zhang (5091608)

“…</p>Results<p>This study demonstrated that menthone, the primary component of Mentha haplocalyx EO, exhibited notable antifungal activity against Fusarium proliferatum (EC50 = 6.099 mmol/L). The treatment significantly inhibited hyphal growth, reduced spore germination rates from 31.49 to 4.95%, decreased spore viability from 46.88 to 20.91%, and reduced spore production by a factor of 17.92 compared with the control group while simultaneously enhancing cell membrane permeability. …”

Data_Sheet_1_Budding and explosive membrane vesicle production by hypervesiculating Escherichia coli strain ΔrodZ.PDF by Yoshihiro Ojima (9421565)

“…<p>Escherichia coli produces extracellular vesicles called outer membrane vesicles. In this study, we investigated the mechanism underlying the hypervesiculation of deletion mutant ΔrodZ of E. coli. …”

Image_2_The COPII subunit MoSec24B is involved in development, pathogenicity and autophagy in the rice blast fungus.tif by Hui Qian (110856)

“…In this process, COPII vesicles are responsible for transporting cargo proteins from the ER to the Golgi. Here, we identified the inner shell subunit of COPII vesicles (MoSec24B) and explored the importance of MoSec24B in the rice blast fungus. …”

Table_1_Photoreceptor Degeneration in Pro23His Transgenic Rats (Line 3) Involves Autophagic and Necroptotic Mechanisms.docx by Kiana Kakavand (9593654)

“…<p>Photoreceptor death contributes to 50% of irreversible vision loss in the western world. …”