Image_1_Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial.PDF by Mads N. Thomsen (13270053)

“…</p>Methods<p>In order to determine the additional effect of carbohydrate restriction in addition to a fixed body weight loss, we randomly assigned 72 adults with T2D and obesity (mean ± SD HbA_1c 7.4 ± 0.7%, BMI 33 ± 5 kg/m²) to a carbohydrate-reduced high-protein diet (CRHP; energy percent from carbohydrate/protein/fat: 30/30/40) or an isocaloric conventional diabetes diet (CD; 50/17/33) for 6 weeks. …”

Table_1_Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial.PDF by Mads N. Thomsen (13270053)

“…</p>Methods<p>In order to determine the additional effect of carbohydrate restriction in addition to a fixed body weight loss, we randomly assigned 72 adults with T2D and obesity (mean ± SD HbA_1c 7.4 ± 0.7%, BMI 33 ± 5 kg/m²) to a carbohydrate-reduced high-protein diet (CRHP; energy percent from carbohydrate/protein/fat: 30/30/40) or an isocaloric conventional diabetes diet (CD; 50/17/33) for 6 weeks. …”

Table_2_Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial.PDF by Mads N. Thomsen (13270053)

“…</p>Methods<p>In order to determine the additional effect of carbohydrate restriction in addition to a fixed body weight loss, we randomly assigned 72 adults with T2D and obesity (mean ± SD HbA_1c 7.4 ± 0.7%, BMI 33 ± 5 kg/m²) to a carbohydrate-reduced high-protein diet (CRHP; energy percent from carbohydrate/protein/fat: 30/30/40) or an isocaloric conventional diabetes diet (CD; 50/17/33) for 6 weeks. …”

Multi-phase Paleozoic magmatism in the North Qaidam ultrahigh-pressure metamorphic units, NW China: implications for transition from continental collision to extensional collapse by Wentao Ji (12256075)

“…Simultaneously, the pronounced decreasing in La/Yb and Sr/Y ratios of magmatic rocks (age of 460 ~ 350 Ma) suggested that the crustal thickness decreased gradually from syn-collisional to post-collisional stage.…”

Data_Sheet_1_Spatial-temporal clustering of an outbreak of SARS-CoV-2 Delta VOC in Guangzhou, China in 2021.docx by Qian Zhang (49333)

“…</p>Results<p>The result of the Knox analysis showed that the areas at short distances and brief periods presented a relatively high risk. The strength of clustering of male-male pairs was higher. …”

S1 Data - by Ergang Wang (1459321)

“…Meanwhile, plant extract-related treatments significantly increased plant physiological properties and TP (Total protein) content, and decreased the content of MDA (malondialdehyde) by 15.70% -36.59% and PRO (proline) by 30.13% -148.44%. …”

DataSheet_1_177Lu-labeled PSMA targeting therapeutic with optimized linker for treatment of disseminated prostate cancer; evaluation of biodistribution and dosimetry.docx by Ayman Abouzayed (17051256)

“…The binding of [¹⁷⁷Lu]Lu-BQ7876 to living cells was characterized by rapid association, while the dissociation included a rapid and a slow phase with affinities K_D1 = 3.8 nM and K_D2 = 25 nM. …”

Path regulates glial proliferation via the mTOR-S6K pathway. by Qian Dong (414788)

“…Brain lobes are circled with yellow dashed lines. Scale bar = 50 μm. Error bar represents SEM. In <b>(F)</b>: One-way ANOVA, (****) <i>P</i> < 0.0001; Welch’s <i>t</i> test, (****) <i>P</i> < 0.0001. …”

Relationship between YAP N/C ratio and cell spreading states of single B2B cells on 2-kPa hydrogels substrates. by Qin Luo (2182514)

“…<p>(<b>A</b>) 3D fluorescent confocal YAP image stack of a single spreading B2B cell on 2-kPa substrate at 0.5^th, 5^th, and 10^th hour. …”

Table 1_Avoiding touching until 60 min—contamination of transdermal estradiol gel after physical contact.docx by Yi Cao (229829)

“…In the estradiol gel group, estradiol levels remained stable within the first 30 min (p >0.05), rapidly decreased at 60 min (p <0.001) and remained stable from 60 min to 120 min (p >0.05). …”

Inhibition of the RSK signaling prevents C/EPBβ phosphorylation and stimulates apoptosis in activated lung myofibroblasts. by Martina Buck (82941)

“…</b> The ERK1/2 inhibitor decreased the fold expression of α-SMA (n: 6 per group; 0.24+/−0.11, <i>P</i><0.0001) and TGF-β1 (n: 6 per group; 0.14+/−0.02, <i>P</i><0.0001). …”

Data_Sheet_2_The halophilic bacteria Gracilibacillus dipsosauri GDHT17 alleviates salt stress on perennial ryegrass seedlings.ZIP by Xiangying Li (1946506)

“…</p>Results and discussion<p>A halophilic bacterium strain GDHT17, was isolated from saline soil, which grows in the salinities media with 1.0%, 5.0%, and 10.0% (w/v) NaCl, and identified as Gracilibacillus dipsosauri. …”

Data_Sheet_1_The halophilic bacteria Gracilibacillus dipsosauri GDHT17 alleviates salt stress on perennial ryegrass seedlings.ZIP by Xiangying Li (1946506)

“…</p>Results and discussion<p>A halophilic bacterium strain GDHT17, was isolated from saline soil, which grows in the salinities media with 1.0%, 5.0%, and 10.0% (w/v) NaCl, and identified as Gracilibacillus dipsosauri. …”

Table 1_Correlation between lactate/albumin ratio and 28-day mortality in sepsis-associated acute kidney injury patients.docx by Susu He (10361615)

“…The Kaplan–Meier curves showed that participants having elevated LAR exhibited significantly decreased survival rates. Cox proportional hazards models showed that higher LAR was related to higher 28-day death rate in SA-AKI patients (HR: 1.224, 95% CI: 1.160–1.291, p < 0.001). …”

DataSheet_1_Hyperthyroidism Prevalence in China After Universal Salt Iodization.docx by Chuyuan Wang (10889535)

“…</p>Results<p>After two decades of USI, the prevalence of overt hyperthyroidism (OH), Graves’ disease (GD), severe subclinical hyperthyroidism (severe SCH), and mild subclinical hyperthyroidism (mild SCH) in mainland China was 0.78%, 0.53%, 0.22%, and 0.22%, respectively. OH and GD prevalence were higher in women than in men (OH: 1.16% vs. 0.64%, P<0.001; GD: 0.65% vs. 0.37%, P<0.001).Prevalence was significantly decreased after 60 years-of-age compared with 30–39 years-of-age (OH:0.61% vs. 0.81%, P<0.001; GD: 0.38% vs. 0.57%, P<0.001).Excessive iodine(EI) and deficient iodine(DI) were both related to increased prevalence of OH (odds ratio [OR] 2.09, 95% confidence interval [CI] 1.68–2.59; OR1.35, 95%CI 1.07–1.72, respectively); however, only deficient iodine was associated with increased prevalence of GD (OR1.67, 95%CI 1.30–2.15). …”

DataSheet1_Quantifying the impact of novel metastatic cancer therapies on health inequalities in survival outcomes.pdf by Karolina Zebrowska (17444970)

“…In terms of PFS, the increases in survival inequalities were larger in a relative sense compared with OS. For mBC, PFS inequalities increased by 8.7 (5.9; 11.6) months, or 71.7%, for stratification based on 5 groups; the IG increased by 2.0 (1.3; 2.6) months, or 67.6%. …”

Datasheet1_Low total cholesterol predicts early death in children with hemophagocytic lymphohistiocytosis.zip by Li Xiao (307908)

“…The observed 30-day mortality rate was 19.05% (64/336, 17 were lost to follow-up) and Kaplan-Meier-estimated 3-year survival rate was 61.67% (95% CI, 56.27%–67.59%). DNA-targeted sequencing of HLH-related genes was performed in 173 (49.0%, 173/353) patients (not all patients with suspected pHLH underwent genetic testing), and 29 patients were diagnosed with genetically confirmed pHLH. …”

Table1_Low total cholesterol predicts early death in children with hemophagocytic lymphohistiocytosis.xlsx by Li Xiao (307908)

“…The observed 30-day mortality rate was 19.05% (64/336, 17 were lost to follow-up) and Kaplan-Meier-estimated 3-year survival rate was 61.67% (95% CI, 56.27%–67.59%). DNA-targeted sequencing of HLH-related genes was performed in 173 (49.0%, 173/353) patients (not all patients with suspected pHLH underwent genetic testing), and 29 patients were diagnosed with genetically confirmed pHLH. …”

DataSheet_1_Case report: Excessive daytime sleepiness as a presenting manifestation of autoimmune glial fibrillary acidic protein astrocytopathy.pdf by Mingyang Tang (13798123)

“…Our patient was a 58-year-old male who experienced excessive daytime sleepiness for 50 days following SARS-CoV-2 infection. He was diagnosed with coronavirus disease 2019 on June 1st. …”

Image_2_Toward Assessing Farm-Based Anaerobic Digestate Public Health Risks: Comparative Investigation With Slurry, Effect of Pasteurization Treatments, and Use of Miniature Biorea... by Stephen Nolan (5539115)

“…For comparison, FIB survival in slurry was examined and after 60 days of storage, none of the FIB tested was <1,000 cfu g⁻¹, suggesting that slurry would not be considered safe for land application if FIB thresholds required for AD digestate were to be applied. Taken together we demonstrate that (i) miniature-scale bioreactors are valid proxies of farm-based AD to carry out targeted pathogen survival studies and (ii) in situ AD treatment of slurry prior to land application reduces the level of FIB, independently of pasteurization, which in turn might be indicative of a decreased potential pathogen load to the environment and associated public health risks.…”