First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…In this study, we report the first highly selective HDAC6 inhibitor with hydrazide as the zinc-binding group (ZBG), which displays superior pharmacokinetic properties to the current hydroxamic acid inhibitors. …”

Daily and annual spatial mean precipitation intensity in mm/day from the ERA5 reanalysis estimated as the ration <i>P</i>_<i>t</i>/<i>A</i>_<i>p</i> and the res... by Rasmus E. Benestad (12530330)

Contour plot of the convergence time <i>t</i>* in Eq (6) as a function of and , where , when (A) <i>α</i> = 0.25, (B) <i>α</i> = 1, and (C) <i>α</i> = 5. by Luis Felipe Giraldo (3710578)

Presentation_1_Airway macrophages display decreased expression of receptors mediating and regulating scavenging in early cystic fibrosis lung disease.pdf by Lisa J. M. Slimmen (16464600)

“…</p>Methods<p>Bronchoalveolar lavage fluid (BALF) was collected from 50 children with CF aged 1, 3 or 5 years. BALF cells were analyzed using flow cytometry. …”

Luciferase complementation imaging assay for the interactions of p20 with NbATG8a and NbATG8f. by Yongle Zhang (11355546)

Data Sheet 1_Reduced hemolytic complement activity in the classical pathway (CH50) is a risk factor for poor clinical outcomes of patients with infections: a retrospective analysis... by Hiroyuki Koami (3878434)

“…We divided the patients into three groups based on the normal CH50 range: Low CH50 (< 25 U/mL; n=168), Normal CH50 (25 ≤, < 48 U/mL; n=1273), and High CH50 (48 ≤ U/mL; n=1285).…”

Flow chart depicting the selection process for study participants. by Hyungjong Park (10147327)

pH Dependence of the Stress Regulator DksA by Ran Furman (708916)

Trial sequential analysis of pooled result of effects of cranberry ingestion on UTI incidence in susceptible populations. by Jia-yue Xia (11378687)

Forest plot of UA levels and risk of cognitive impairment with less than 10 years of follow-up. by Qianqian Liu (381114)

Isoflavones prevent bone loss following ovariectomy in young adult rats-0 by Yang-Hwei Tsuang (88998)

“…After ovariectomy (Group B), the mean bone porosities significantly increased to 89.8%, 89.2%, and 85.7% for the femur, spine, and tibia, respectively (P < 0.05). The bone porosities of group C (an isoflavone-rich diet for one month followed by ovariectomy and a normal diet) significantly increased to 85.8%, 86.9%, and 88.2% in the femur, spine, and tibia, repectively, while in Group D (an isoflavone-rich diet for three months), the bone porosities of the femur, spine, and tibia decreased to 59.3%, 66.8%, and 64.0%, respectively, two months after ovariectomy (P < 0.05). …”

DataSheet_1_Hemizygous nonsense variant in the moesin gene (MSN) leads to a new autoimmune phenotype of Immunodeficiency 50.pdf by András L. Kovács (13565251)

“…We present a putative new autoimmune phenotype of Immunodeficiency 50 (MIM300988) characterized by antiphospholipid syndrome, Hashimoto’s thyroiditis, leg ulcers, and juvenile tooth loss, associated with W217X mutation of the MSN gene.…”

Demographic information and baseline population characteristics. by Lu Han (151620)

Comparison of systemic inflammation biomarkers in infected and uninfected populations. by Lu Han (151620)

Receiver operating characteristic curve analyses for the prediction of hepatitis C. by Lu Han (151620)

Exploring the correlation between systemic inflammation biomarkers and HCV infection (logarithm base 2). by Lu Han (151620)

General addictive models demonstrate the relationship between systemic inflammatory biomarkers and anti-HCV. by Lu Han (151620)

Pre-experimental soil characteristics. by Khadim Dawar (11719392)

Participants retention and sexual risk compensation evaluation. by Supattra Rungmaitree (12563948)

Threshold effect analysis of systemic inflammatory biomarkers on hepatitis C using two-piece wise linear regression. by Lu Han (151620)