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Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2.
Published 2018“…In the case of D2HGDH protein, the mutations I147S and V444A that are positioned in the beta sheet region exhibited higher Root Mean Square Deviation (RMSD), decrease in compactness and number of intramolecular hydrogen bonds compared to the mutations N439D and D375Y that are positioned in the turn and loop region, respectively. …”
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apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes.
Published 2021“…Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …”
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Comparative Study on Gas-Sensing Properties of 2D (MoS2, WS2)/PANI Nanocomposites-Based Sensor
Published 2022“…In this study, we proposed a new design of an NH3 gas sensor that was comprised of two-dimensional (TMDs, mainly WS2 and MoS2) and PANI. …”
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Regulation of NKG2D by RKIP: Implications on NK-mediated cytotoxicity and cytokine production
Published 2021“…Hypothesizing that there may be a biochemical link between the two, we examined the potential cross talks of signaling pathways between NKG2D and RKIP. …”
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Study of the Ion Interclation Mechanism in Mxene Membrane for the Water Treatment Applications
Published 2020“…Chapter one consists of the introduction and literature review, which provides an overview of the current conventional technology in water treatment applications and how the two-dimensional nanomaterial can improve it. The high water flow of 2D membrane stems from the well-defined nanometer channels that exhibit low friction for the water flow making high water flux membranes. …”
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Association between Serum Vitamin D Status and Circadian Syndrome: A Cross-Sectional Study
Published 2024“…Results: Our results indicated that low vitamin D levels exhibited meaningful associations with CircS, with vitamin D deficiency and inadequacy demonstrating 2.21-fold (95% CI 1.78-2.74, p < 0.001) and 1.33-fold (95% CI 1.14-1.54, p < 0.001) increases in CircS odds, respectively. …”
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Hyperhydration-induced decrease in urinary luteinizing hormone concentrations of Male athletes in doping control analysis
Published 2019“…However, an adjustment of urinary LH concentrations by specific gravity based on a reference value of 1.020 seems to adequately correct the hyperhydration-induced decrease on the LH levels. - 2019 Human Kinetics, Inc.…”
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Impact Of Fines On Gas Relative Permeability Through Sand Using Pore Networks From 3d Synchrotron Micro-Computed Tomography
Published 2019“…Kaolinite and Montmorillonite fine particles were added in varied concentrations in six soil specimens, each system was scanned at four stages with varied saturations of brine and CO2, resulting in 20 systems. Micro-computed tomography images were processed for 3D visualization, quantification and pore network modeling. …”
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Elucidating the role of interacting residues of the MSH2-MSH6 complex in DNA repair mechanism: A computational approach.
Published 2019“…From the simulation studies, we observed higher deviation, lower protein compactness, and a decrease in the number of intramolecular hydrogen bonds in the mutant W764C MSH2-MSH6 protein complex. …”
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Tailoring the deposition of MoSe2 on TiO2 nanorods arrays via radiofrequency magnetron sputtering for enhanced photoelectrochemical water splitting
Published 2023“…MoSe2/1 D TiO2 nanorods (NRs) heterojunction assembly was systematically fabricated, and its photoelectrocatalytic properties were investigated. …”
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Erratum: ITRAQ-based Quantitative Protein Expression Profiling and MRM Verification of Markers in Type 2 Diabetes (Journal of Proteome Research (2012) 11 (5527-5537) DOI: 10.1021/p...
Published 2013“…As expected, the diabetic cohort showed an elevation in serum glucose, HbA1c, and insulin levels and a decrease in the serum levels of Vitamin D and HDL .Addition/Correctionpubs.acs.org/jpr © 2013 American Chemical Society 1065 dx.doi.org/10.1021/pr4000224 | J. …”
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Characteristics of olive mill solid residue and its application in remediation of Pb2+, Cu2+ and Ni2+ from aqueous solution: Mechanistic study
Published 2014“…Meanwhile, at lower pH values the uptake capacity decreased. It was found that the qmax values are (0.54, 0.59 and 0.63), (0.46, 0.63, and 0.69) and (0.31, 0.42, and 0.47) meq/g for Pb2+ Cu2+ and Ni2+ at 298, 308, and 328 K; respectively. …”
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Adaptive thermal comfort in the different buildings of Darjeeling Hills in eastern India – Effect of difference in elevation
Published 2018“…Thermal comfort standards are required to provide comfortable indoor condition which has a positive effect on the occupant. However, the Predicted Mean Vote – Percentage People Dissatisfied (PMV-PPD) model which is used to determine the indoor comfort in most of the international standards fails often, especially in naturally ventilated buildings. …”
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Maximum Likelihood Estimation in the Inverse Weibull Distribution with Type II Censored Data
Published 2022“…We found that the parameter estimators are almost unbiased, while the MRL and TVaR estimators are asymptotically unbiased. Moreover, the mean squared error of all estimators decreased for larger sample sizes and it increased when the censoring proportion is increased for a fixed sample size. …”
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Computational model to analyze and characterize the functional mutations of NOD2 protein causing inflammatory disorder - Blau syndrome.
Published 2020“…Therefore, we further performed homology modeling to determine the 3D structure of native NOD2 and the W490L mutant. …”
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Assessment of Dapagliflozin Effectiveness as Add-on Therapy for the Treatment of Type 2 Diabetes Mellitus in a Qatari Population
Published 2019“…Eighty-one Qatari patients were found to have received dapagliflozin during the study period; 72% of them (n = 58) were males, with a mean age of 57.0 ± 9.0 years and a mean baseline HbA1c of 9.0 ± 1.4%. …”
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