Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects حسب Alsaad A.M.

"…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …"
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Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes حسب Younes, Noura B.

"…The exposure of adipocytes to 1% hypoxia significantly alters the transcript of hypoxia genes, and other genes involved in glucose (GLUT1, GLUT4) and lipid (PPAR-γ) metabolism, and is also linked to anaerobic metabolism with apoptosis and increased oxidative stress. …"
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Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. حسب P, Sneha

"…Galactosemia type 2 is an autosomal recessive disorder characterized by the deficiency of galactokinase (GALK) enzyme due to missense mutations in GALK1 gene, which is associated with various manifestations such as hyper galactosemia and formation of cataracts. …"
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Opportunities, challenges and trade-offs with decreasing avoidable food waste in the UK حسب Patel, Shivalee

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Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients حسب Al-Amleh, Esraa K.

"…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM). (4) Conclusion: Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …"
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MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels. حسب Gomes da Silva, Isaura Isabelle Fonseca

"…No significant differences were observed for MYD88 gene expression (FC = 1.20; p = 0.294) between patients and controls analyzed. …"
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Credit bureaus and financial constraints do corruption matter? حسب Ben Ali, Mohamed Sami

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Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanis... حسب Anwar-Mohamed, Anwar

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A robust experimental-based artificial neural network approach for photovoltaic maximum power point identification considering electrical, thermal and meteorological impact حسب Gowid, Samer

"…The results showed a decrease in the MSE of Vmp by 74.3% (from 1.6 V to 0.411 V), and in the MSE of Imp by 95% (from 4.4e−6 A to 2.16e−7 A), respectively. …"
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Novel potentials of the DPP-4 inhibitor sitagliptin against ischemia-reperfusion (I/R) injury in rat ex-vivo heart model حسب Al-Awar A.

"…Hearts were then isolated and subjected to two different I/R injury protocols: 10 min perfusion, 45 min regional ischemia, and 120 min reperfusion for infarct size (IS) measurement, or: 10 min perfusion, 45 min regional ischemia and 10 min reperfusion for biochemical analysis: nitric oxide synthases (NOSs) and DPP-4 activity, glucagon-like peptide-1 (GLP-1), Calcium, transient receptor potential vanilloid (TRPV)-1 and calcitonin gene-related peptide (CGRP) levels, transient receptor potential canonical (TRPC)-1 and e-NOS protein expression. …"
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Effects of superelastic nano-NiTi additions on electroless Ni –P coating properties under bending حسب MacLean M.

"…In this study, electroless Ni –P-nano-NiTi composite coatings containing 5.14 wt%, 6.07 wt%, and 7.02 wt % NiTi were subjected to three-point bend testing in order to determine bending properties. …"
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PROFILE OF OXIDATIVE STRESS GENES IN RESPONSE TO OBESITY TREATMENT حسب AHMED, AMIRA

"…Aim: This study explores the impact of SNF on OS in diet induced obese (DIO) mice via profiling of OS genes and pathways in skeletal muscles related to the anti-obesity effect. …"
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Turning point in COVID-19 severity and fatality during the pandemic: a national cohort study in Qatar حسب Chemaitelly, Hiam

"…In the pre-omicron phase, first omicron wave, and combined phases, it was 2.01 (95% CI 1.90 to 2.13), 3.70 (95% CI 3.25 to 4.22) and 2.18 (95% CI 2.07 to 2.30) per 1000 person years, respectively. …"
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies حسب Fawaz E., Alanazi

"…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …"
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies حسب Fawaz E., Alanazi

"…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …"
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Understanding the False Positive of Modified Martensitic Steels in Sweet & Sour Service Conditions Using a Point Defect Model Perspective حسب Martinez, Alan

"…These results indicate a critical point in temperature in the tests with only CO2, where resistance to pitting susceptibility is maximized due to a decrease in the cation vacancy diffusivity.…"
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INTERACTION BETWEEN CLOCK GENE AND LIFESTYLE FACTOR IN RELATION TO OBESITY RISK FACTOR حسب ABDULKADER, HADIL

"…Women showed a strong association with obesity compared to men (OR: 1.51, 95% CL: 1.32-1.73), while smokers and ex-smokers had a decreased odds of having obesity by 21% and 12% respectively in comparison to nonsmokers. …"
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In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway حسب Kuttikrishnan, Shilpa

"…Moreover, NSP-B suppressed FOXM1-regulated genes, such as Aurora Kinases A and B, CDKs 4 and 6, and PLK1. …"
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Identification of key genes regulating macronutrient accumulation and final yield in wheat under potassium deficiency حسب Thabet, Samar G.

"…Interestingly, the TraesCS1B02G359800 gene was located on chromosome 3B and annotated as protein kinases that harbor the variation of NGS, P, Mg_K2, and Mg_K1. …"
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The Interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets حسب Cenciarelli, Carlo

"…In the current study, we assessed the effects of Hes1-targeted shRNA, a Notch1 gene target, specifically on GBM CSC refractory to GSI-X. …"
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