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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes.
Published 2021“…Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …”
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Therapeutic outcomes and biodistribution of gold nanoparticles in collagen-induced arthritis animal model
Published 2022“…The role of gold nanoparticles (AuNPs) in the treatment of autoimmune diseases remains mysterious. …”
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Developmental Toxicity of Surface-Modified Gold Nanorods in the Zebrafish Model
Published 2022“…Accordingly, this study aims to evaluate the acute and developmental toxicity of surfacemodified gold nanorods (AuNRs), on zebrafish (Danio rerio) early life stages. …”
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Emerging clay-aryl-gold nanohybrids for efficient electrocatalytic proton reduction
Published 2018“…Successful intercalation was confirmed by the detection of F1s peak in X-ray photoelectron spectroscopy (XPS) at ∼689 eV, in line with fluorine in CF bonds, and the reduction of gold (III) into metallic gold. …”
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Quercetin Loaded Silica and Gold - Coated Silica Nanoparticles: Characterization, Evaluation and Comparison of Their in vitro Characteristics
Published 2023“…The intensity of FTIR peaks of silica NPs has been significantly decreased upon gold coating indicating a successful attachment of the gold thin layer. …”
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Effect of Hyperglycemia on eNOS function in EPCs
Published 2020“…ROS was assessed using CellROX stain following 1 and 3 days of treatment. Results showed that both acute and chronic hyperglycemia showed a trend towards decrease in phosphorylation of eNOS and Akt. …”
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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation...
Published 2019“…The molecular interaction study also revealed that the co-crystallized AKT1 inhibitor N-(4-(5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)-3H-imidazo [4,5-b]pyridin-3-yl)benzyl)-3-fluorobenzamide (12j) exhibited a better interaction with native AKT1 compared with the E17K mutant AKT1 protein, whereas, Akti-1/2 exhibited the opposite effects, i.e., a better interaction with the E17K mutant AKT1 than the native AKT1. …”
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Chemical characterization and evaluation of antimicrobial and cutaneous wound healing potentials of gold nanoparticles using Allium saralicum R.M. Fritsch
Published 2020“…The aims of this study were to synthesize gold nanoparticles from aqueous extract of Allium saralicum R.M. …”
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Assessment And Classification Of Transit Stations For Transit Oriented Development (Tod) Potential Using Node-Place Model: The Case Of Doha Gold Metro Line
Published 2018“…Research aims to assess, compare and classify the gold line metro stations, by identifying potential for TOD type development. …”
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Allergenicity of roasted peanuts treated with a non-human digestive protease
Published 2015“…Results indicate that alcalase digestion of sonicated peanuts significantly increased protein solubility while decreasing Ara h 1 and Ara h 2 concentrations in both soluble and insoluble portions of peanuts relative to untreated peanuts. …”
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Use and assessment of “e-plastics” as recycled aggregates in cement mortar
Published 2019“…The obtained results, for all RPs, (especially those of 7.5% and 10%) exhibited an increase in the CS of the specimens by 15.4% and 7.8%, respectively, with the MoE decreased in both cases by 18.1% and 23.8%, respectively. …”
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